在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human immunodeficiency virus type 1 group M subtype B Protein Rev (rev)

  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group M subtype B Protein Rev(rev)
  • 貨號:
    CSB-YP300244HKQ
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group M subtype B Protein Rev(rev)
  • 貨號:
    CSB-EP300244HKQ
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group M subtype B Protein Rev(rev)
  • 貨號:
    CSB-EP300244HKQ-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group M subtype B Protein Rev(rev)
  • 貨號:
    CSB-BP300244HKQ
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human immunodeficiency virus type 1 group M subtype B Protein Rev(rev)
  • 貨號:
    CSB-MP300244HKQ
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    rev
  • Uniprot No.:
  • 別名:
    rev; Protein Rev; ART/TRS; Anti-repression transactivator; Regulator of expression of viral proteins
  • 種屬:
    Human immunodeficiency virus type 1 group M subtype B (isolate HXB3) (HIV-1)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-116
  • 氨基酸序列
    MAGRSGDSDE DLLKAVRLIK FLYQSNPPPN PEGTRQARRN RRRRWRERQR QIHSISERIL STYLGRSAEP VPLQLPPLER LTLDCNEDCG TSGTQGVGSP QILVESPTIL ESGAKE
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Escorts unspliced or incompletely spliced viral pre-mRNAs (late transcripts) out of the nucleus of infected cells. These pre-mRNAs carry a recognition sequence called Rev responsive element (RRE) located in the env gene, that is not present in fully spliced viral mRNAs (early transcripts). This function is essential since most viral proteins are translated from unspliced or partially spliced pre-mRNAs which cannot exit the nucleus by the pathway used by fully processed cellular mRNAs. Rev itself is translated from a fully spliced mRNA that readily exits the nucleus. Rev's nuclear localization signal (NLS) binds directly to KPNB1/Importin beta-1 without previous binding to KPNA1/Importin alpha-1. KPNB1 binds to the GDP bound form of RAN (Ran-GDP) and targets Rev to the nucleus. In the nucleus, the conversion from Ran-GDP to Ran-GTP dissociates Rev from KPNB1 and allows Rev's binding to the RRE in viral pre-mRNAs. Rev multimerization on the RRE via cooperative assembly exposes its nuclear export signal (NES) to the surface. Rev can then form a complex with XPO1/CRM1 and Ran-GTP, leading to nuclear export of the complex. Conversion from Ran-GTP to Ran-GDP mediates dissociation of the Rev/RRE/XPO1/RAN complex, so that Rev can return to the nucleus for a subsequent round of export. Beside KPNB1, also seems to interact with TNPO1/Transportin-1, RANBP5/IPO5 and IPO7/RANBP7 for nuclear import. The nucleoporin-like HRB/RIP is an essential cofactor that probably indirectly interacts with Rev to release HIV RNAs from the perinuclear region to the cytoplasm.
  • 亞細胞定位:
    Host nucleus, host nucleolus. Host cytoplasm.
  • 蛋白家族:
    HIV-1 REV protein family


主站蜘蛛池模板: 亚洲日韩国产精品第一页一区| 又黄又爽又色的免费网站| 99久久99视频只有精品| 色妞www精品视频| 亚洲欧美一区二区成人片| 久久久亚洲欧洲日产国码αv| 在线视频免费无码专区| 欲香欲色天天综合和网| 亚洲熟女乱色综合亚洲图片| 超碰aⅴ人人做人人爽| 丰满人妻熟妇乱又伦精品app| 欧美最猛黑人xxxxx猛交| 在线视频免费观看爽爽爽| 国产女人高潮嗷嗷嗷叫| 色欲天天婬色婬香视频综合网| 人妻av中文字幕无码专区| 性生交大全免费看| 人妻巨大乳挤奶水hd免费看| 亚洲欧美日韩另类丝袜一区| 真人抽搐一进一出视频| 毛色毛片免费观看| 久久亚洲道色综合久久| 无码人妻斩一区二区三区| 在线亚洲人成电影网站色www| 人成午夜大片免费视频77777| 日韩加勒比一本无码精品| 欧美日韩国产综合新一区| 极品少妇xxxx| 中文字幕亚洲制服在线看| 欧美亚洲熟妇一区二区三区| 欧美极品少妇×xxxbbb| 凹凸国产熟女精品视频| 久久精品国产99久久久小说| 国产又色又爽又黄的免费 | 水蜜桃av导航| 色情一区二区三区免费看| 亚洲精品无码成人网站| 国产在线乱子伦一区二区| 3d动漫精品啪啪一区二区下载 | 亚洲人毛茸茸bbxx| 色依依av在线|