在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Zinc transporter 4 (SLC30A4), partial

  • 中文名稱(chēng):
    人SLC30A4重組蛋白
  • 貨號(hào):
    CSB-YP021569HU1
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
    人SLC30A4重組蛋白
  • 貨號(hào):
    CSB-EP021569HU1
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
    人SLC30A4重組蛋白
  • 貨號(hào):
    CSB-EP021569HU1-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
    人SLC30A4重組蛋白
  • 貨號(hào):
    CSB-BP021569HU1
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
    人SLC30A4重組蛋白
  • 貨號(hào):
    CSB-MP021569HU1
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SLC30A4
  • Uniprot No.:
  • 別名:
    SLC30A4; ZNT4; Zinc transporter 4; ZnT-4; Solute carrier family 30 member 4
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment.
  • 基因功能參考文獻(xiàn):
    1. There was a significant increase in protein levels of ZnT4 in the prefrontal cortex in Major depression disorder, relative to control subjects. PMID: 27661418
    2. TRPML1 works in concert with ZnT4 to regulate zinc translocation between the cytoplasm and lysosomes. PMID: 23368743
    3. The loss of ZnT4 in airway inflammation contributes to airway epithelium vulnerability in diseases such as asthma. PMID: 22254085
    4. Genomic localization, organization; exclusion in variants of acrodermatitis enteropathica. PMID: 11686514
    5. not responsible for acrodermatitis enteropathica in Japanese families PMID: 11935329
    6. hZnT4 is constitutively expressed in the human breast and may be one of the several members of the ZnT family involved in the transport of zinc into milk PMID: 11988082
    7. The hZnT4 protein did not co-localise with intracellular free zinc pools, suggesting that hZnT4 is not involved in transport of zinc into vesicles destined for secretion into milk. PMID: 12743795
    8. decreased intensity of ZnT4 immunoreactivity occurred in the progression from benign to invasive localized prostate cancer and to metastatic disease PMID: 12955079
    9. Decreased hZnT-4 expression is associated with prostate tissue abnormalities independent of total cellular zinc content. PMID: 14968438
    10. findings implicate a role for ZnT(4) in mast cell Zn homeostasis and suggest that granule pools of Zn may be distinct from those regulating activation of procaspase-3 and NF-kappaB. PMID: 15187159
    11. Our results show that Zn transporter-4 and Zn transporter-6 are significantly (P<0.05) increased in hippocampus/parahippocampal gyrus of early Alzheimer's disease and Alzheimer's disease subjects. PMID: 16580781
    12. hZnT-4 is found in the plasma membrane. It is most highly expressed in Molt-4 cells, up-regulated after treatment with phytohemagglutinin & is responsible for the measured decrease of intracellular zinc content after high zinc exposure. PMID: 17971500
    13. Data show that ZNT4 is extensively present in the Abeta-positive plaques in the cortex of human AD brains. PMID: 18639746

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Endosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 11015

    OMIM: 602095

    KEGG: hsa:7782

    STRING: 9606.ENSP00000261867

    UniGene: Hs.162989



主站蜘蛛池模板: 日本一本一区二区免费播放| 一个色综合国产色综合| 邻居少妇张开腿让我爽了一夜| 国产精品卡一卡2卡三卡网站| 中字幕视频在线永久在线观看免费| 中文字幕无码不卡一区二区三区 | 国产女人高潮嗷嗷嗷叫| 天堂在/线资源中文在线8| 茄子视频国产在线观看| 69精品人人人人| 免费看又黄又爽又猛的视频软件| 免费国产午夜视频在线观看| 无码国产精品一区二区免费16| 精品久久久久久久久久中文字幕 | 韩国无码av片在线观看| 亚洲成成品网站源码中国有限公司 | 无码国产精品成人| 天天躁日日躁狠狠躁免费麻豆| 337p西西人体大胆瓣开下部| 大香伊蕉在人线国产最新75| 少妇激情艳情综合小视频| 日韩精品一区二区在线观看| 国产乱码日产精品bd| 伊人久久大香线蕉综合影院首页| 成年美女黄网站色大免费全看| 樱花草在线社区www| 国产成人mv视频在线观看| 国产在线视频一区二区三区98| 中文在线8资源库| 白丝美女被狂躁免费视频网站| 在线观看国产精品乱码app| 一边吃奶一边摸做爽视频| 又粗又大又硬毛片免费看| 日韩人妻无码精品专区906188| 中文字幕日韩人妻无码| 日韩欧美一区二区三区免费观看| 亚洲精品色无码av试看| 国产精品一区二区av交换| 久久99亚洲精品久久99果| 2020国产欧洲精品网站| 色偷偷亚洲第一成人综合网址|