在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Zinc transporter 4 (SLC30A4), partial

  • 中文名稱(chēng):
    人SLC30A4重組蛋白
  • 貨號(hào):
    CSB-YP021569HU1
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱(chēng):
    人SLC30A4重組蛋白
  • 貨號(hào):
    CSB-EP021569HU1
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱(chēng):
    人SLC30A4重組蛋白
  • 貨號(hào):
    CSB-EP021569HU1-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱(chēng):
    人SLC30A4重組蛋白
  • 貨號(hào):
    CSB-BP021569HU1
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱(chēng):
    人SLC30A4重組蛋白
  • 貨號(hào):
    CSB-MP021569HU1
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SLC30A4
  • Uniprot No.:
  • 別名:
    SLC30A4; ZNT4; Zinc transporter 4; ZnT-4; Solute carrier family 30 member 4
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment.
  • 基因功能參考文獻(xiàn):
    1. There was a significant increase in protein levels of ZnT4 in the prefrontal cortex in Major depression disorder, relative to control subjects. PMID: 27661418
    2. TRPML1 works in concert with ZnT4 to regulate zinc translocation between the cytoplasm and lysosomes. PMID: 23368743
    3. The loss of ZnT4 in airway inflammation contributes to airway epithelium vulnerability in diseases such as asthma. PMID: 22254085
    4. Genomic localization, organization; exclusion in variants of acrodermatitis enteropathica. PMID: 11686514
    5. not responsible for acrodermatitis enteropathica in Japanese families PMID: 11935329
    6. hZnT4 is constitutively expressed in the human breast and may be one of the several members of the ZnT family involved in the transport of zinc into milk PMID: 11988082
    7. The hZnT4 protein did not co-localise with intracellular free zinc pools, suggesting that hZnT4 is not involved in transport of zinc into vesicles destined for secretion into milk. PMID: 12743795
    8. decreased intensity of ZnT4 immunoreactivity occurred in the progression from benign to invasive localized prostate cancer and to metastatic disease PMID: 12955079
    9. Decreased hZnT-4 expression is associated with prostate tissue abnormalities independent of total cellular zinc content. PMID: 14968438
    10. findings implicate a role for ZnT(4) in mast cell Zn homeostasis and suggest that granule pools of Zn may be distinct from those regulating activation of procaspase-3 and NF-kappaB. PMID: 15187159
    11. Our results show that Zn transporter-4 and Zn transporter-6 are significantly (P<0.05) increased in hippocampus/parahippocampal gyrus of early Alzheimer's disease and Alzheimer's disease subjects. PMID: 16580781
    12. hZnT-4 is found in the plasma membrane. It is most highly expressed in Molt-4 cells, up-regulated after treatment with phytohemagglutinin & is responsible for the measured decrease of intracellular zinc content after high zinc exposure. PMID: 17971500
    13. Data show that ZNT4 is extensively present in the Abeta-positive plaques in the cortex of human AD brains. PMID: 18639746

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Endosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 11015

    OMIM: 602095

    KEGG: hsa:7782

    STRING: 9606.ENSP00000261867

    UniGene: Hs.162989



主站蜘蛛池模板: 青青草视频免费观看| 农民人伦一区二区三区| 久久精品蜜芽亚洲国产av| 92电影网午夜福利| 欧美高清freexxxx性| 亚洲红杏成在人线免费视频| 天天躁夜夜踩很很踩2022| 亚洲熟妇久久国产精品| 国产国产成人久久精品| 国内午夜熟妇又乱又伦| 国产老熟妇精品观看| 40岁成熟女人牲交片20分钟| 国产午夜精品理论片| 欧美video性欧美熟妇| av无码人妻波多野结衣| 久久人妻夜夜做天天爽| 国产98在线 | 免费、| 好男人www社区| 亚洲无线观看国产精品| 久久亚洲精品成人无码网站夜色| 国产强伦姧在线观看无码| 成 人 网 站 免费观看| 性生交大片免费看女人按摩| 99国产欧美久久久精品蜜芽| 免费人成网站在线观看不卡| 尤物色综合欧美五月俺也去| 国产精品自在在线午夜免费| 久久久久久久97| 人人妻人人澡人人爽人人精品浪潮| 亚洲精品一区国产| 欧美亚洲另类 丝袜综合网| 精品无码久久久久国产app| 国产网红无码精品视频| 日本熟妇人妻xxxxx| 国产女人喷潮视频免费| 688欧美人禽杂交狂配| 美女扒开大腿让男人桶| 精品产区wnw2544| 免费看美女部位隐私网站| 亚洲国产欧美在线人成aaaa| 少妇被爽到高潮喷水久久欧美精品|