在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Zinc fingers and homeoboxes protein 1 (ZHX1), partial

Recombinant Human Zinc fingers and homeoboxes protein 1 (ZHX1), partial

  • 中文名稱：
    人ZHX1重組蛋白
  • 貨號：
    CSB-YP891955HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人ZHX1重組蛋白
  • 貨號：
    CSB-EP891955HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人ZHX1重組蛋白
  • 貨號：
    CSB-EP891955HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人ZHX1重組蛋白
  • 貨號：
    CSB-BP891955HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人ZHX1重組蛋白
  • 貨號：
    CSB-MP891955HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ZHX1
  • Uniprot No.：
  • 別名：
    ZHX 1; ZHX1; ZHX1_HUMAN; Zinc finger and homeodomain protein 1; Zinc fingers and homeobox 1; Zinc fingers and homeoboxes 1; Zinc fingers and homeoboxes protein 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as a transcriptional repressor. Increases DNMT3B-mediated repressive transcriptional activity when DNMT3B is tethered to DNA. May link molecule between DNMT3B and other co-repressor proteins.
  • 基因功能參考文獻：
    1. ZHX1 expression is correlated with renal cell carcinoma progression and poor survival. PMID: 28152006
    2. ZHX1 was found to play essential roles in the proliferation, migration, and invasion of cholangiocarcinoma cells, and its effect on the proliferation was mediated partially through EGR1. PMID: 27835650
    3. together, this study demonstrates that ZHX1 plays crucial roles in the progression of glioblastoma, and its findings suggest that ZHX1 be viewed as a potential prognostic maker and therapeutic target of glioblastoma. PMID: 28351300
    4. miR-199a-3p may function as a novel tumor promoter in gastric cancer and its oncogenic activity may involve the direct targeting and inhibition of ZHX1 PMID: 25448600
    5. Low expression of ZHX1 may be responsible for hepatocarcinogenesis. PMID: 24064680
    6. Study showed that ZHX1 is SUMOylated by Ubc9 with SUMO1 at the sites K159, K454, and K626 and that the SUMOylation of ZHX1 regulated the stability, ubiquitination and transcriptional activity of ZHX1. PMID: 23686912
    7. This study characterized features of ZHX-1 involved in nuclear localization, dimerization, and transcriptional activity, and mapped these domains. PMID: 12237128
    8. a search of ZHX1-interacting proteins using a yeast two-hybrid system PMID: 12659632
    9. ZHX proteins 1, 2 and 3 are major transcriptional mediators of podocyte disease PMID: 17056598
    10. ZHX1 enhanced the transcriptional repression mediated by DNMT3B when DNMT3B is directly targeted to DNA. These results showed for the first the direct linkage between DNMT and zinc-fingers homeoboxes protein, leading to enhanced gene silencing by DNMT3B PMID: 17303076
    11. structure of the tandem zinc-finger region of human ZHX1 PMID: 19348505

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Note=Colocalized in the nucleus with DNMT3B.
  • 蛋白家族：
    ZHX family
  • 組織特異性：
    Ubiquitously expressed. Expressed in podocytes.
  • 數據庫鏈接：

    HGNC: 12871

    OMIM: 604764

    KEGG: hsa:11244

    STRING: 9606.ENSP00000297857

    UniGene: Hs.521800



主站蜘蛛池模板： 国产精品激情欧美可乐视频| 中文字幕卡二和卡三的视频| 伊人久久久av老熟妇色| 少妇被粗大的猛进出69影院| 永久黄网站色视频免费看| 亚洲爆乳aaa无码专区| 又大又硬又黄的免费视频| 午夜家庭影院| 精品国产不卡一区二区三区 | 欧洲精品码一区二区三区免费看 | 天天躁日日躁aaaxxⅹ| 亚洲人成网站18禁止一区| 最新高清无码专区| 日本极品少妇xxxx| 成人试看30分钟免费视频| 黑人尾随强伦姧人妻爽翻天| 国产av国片精品有毛| 大肉大捧一进一出好爽视频mba| 麻豆av福利av久久av| 双腿张开被9个男人调教| 黄网站成人片免费视频 | 人妻无码中文专区久久五月婷| 熟女性饥渴一区二区三区| 精品一区二区不卡无码av| 国产精品狼人久久久久影院| 色一乱一伦一图一区二区精品| 亚洲中文无码线在线观看| 亚洲 小说 欧美 激情 另类| 亚洲乱码精品久久久久..| 国产美女视频免费观看的网站| 国产饥渴孕妇在线播放| 亚洲成av人片在线观看不卡| 无套内射极品少妇chinese| 亚洲色播爱爱爱爱爱爱爱| 日本国产网曝视频在线观看| 精品国产在天天在线观看| 色噜噜狠狠狠综合曰曰曰| 黑巨人与欧美精品一区| 乱人伦视频中文字幕| 果冻传媒亚洲区二期| 天堂在线观看www|