在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Zinc finger protein castor homolog 1 (CASZ1), partial

Recombinant Human Zinc finger protein castor homolog 1 (CASZ1), partial

  • 中文名稱：
    Recombinant Human Zinc finger protein castor homolog 1(CASZ1) ,partial
  • 貨號：
    CSB-YP773036HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Zinc finger protein castor homolog 1(CASZ1) ,partial
  • 貨號：
    CSB-EP773036HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Zinc finger protein castor homolog 1(CASZ1) ,partial
  • 貨號：
    CSB-EP773036HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Zinc finger protein castor homolog 1(CASZ1) ,partial
  • 貨號：
    CSB-BP773036HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Zinc finger protein castor homolog 1(CASZ1) ,partial
  • 貨號：
    CSB-MP773036HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    2410019P08Rik; AV096627; BC040081; BOS_15820; Castor-related protein; CASZ1; CASZ1_HUMAN; CST; D4Ertd432e; dJ734G22.1; FLJ12223; FLJ20321; MGC155102; MGC31683; OTTMUSP00000011746; OTTMUSP00000011748; Putative survival-related protein; RP23-230I5.1; RP4-734G22.2; SRG; Survival related; Zinc finger protein 693; Zinc finger protein castor homolog 1; ZNF693
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcriptional activator. Involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7.
  • 基因功能參考文獻：
    1. Collectively, our proteomic, biochemical, genetic, and structural studies suggest that the physical interaction between TBX20 and CASZ1 is required for cardiac homeostasis, and further, that reduction or loss of this critical interaction leads to dilated cardiomyopathy (DCM) PMID: 28945738
    2. These findings provide insight into mechanisms by which CASZ1 regulates transcription, and suggests that regulation of CASZ1 subcellular localization may impact its function in normal development and pathologic conditions such as NB tumorigenesis. PMID: 27270431
    3. The current study reveals CASZ1 as a new gene responsible for human dilated cardiomyopathy (DCM), which provides novel mechanistic insight and potential therapeutic target for CASZ1-associated DCM, implying potential implications in improved prophylactic and therapeutic strategies for DCM, the most common type of primary myocardial disease. PMID: 28099117
    4. the current study firstly identifies CASZ1 as a new gene predisposing to congenital heart disease in humans PMID: 27693370
    5. CASZ1b binds to chromatin and recruits NuRD complexes to orchestrate epigenetic-mediated transcriptional programs PMID: 26296975
    6. CASZ1 inhibits cell cycle progression in neuroblastoma by restoring retinoblastoma protein activity. PMID: 23892435
    7. Papillomavirus DNA integration is associated with loss of CASZ1 gene and thus cervical carcinogenesis. PMID: 22262398
    8. This study identifies key domains needed for CASZ1b to regulate gene transcription; a link between loss of CASZ1b transcriptional activity and attenuation of CASZ1b-mediated inhibition of neuroblastoma growth and tumorigenicity PMID: 22331471
    9. determined that the tumor suppressors CLU, NGFR, and RUNX3 were also directly repressed by EZH2 like CASZ1 in NB cells PMID: 22068036
    10. CASZ1 is a critical modulator of neural cell development, and that somatically acquired disruption of normal CASZ1 expression contributes to the malignant phenotype of human Neuroblastoma. PMID: 21252912
    11. The study indicates that although their mechanisms of regulation may be distinct, both CASZ1b and CASZ1a have largely redundant but critical roles in suppressing tumor cell growth. PMID: 21490919
    12. CASZ1 is expressed in a number of human tumors and localizes to a chromosomal region frequently lost in tumors of neuroectodermal origin. PMID: 16631614

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in heart, lung, skeletal muscle, pancreas, testis, small intestine, and stomach, but it is not detectable in the adult brain.
  • 數據庫鏈接：

    HGNC: 26002

    OMIM: 609895

    KEGG: hsa:54897

    STRING: 9606.ENSP00000366221

    UniGene: Hs.439894



主站蜘蛛池模板： 东京热大乱系列无码| 狠狠色噜噜狠狠狠888米奇| 18禁超污无遮挡无码免费动态图 | 国产精品玖玖玖在线| 国产日产欧美最新| 色妞ww精品视频7777| 亚洲另类无码一区二区三区| 日本少妇裸体做爰高潮片 | 99久久久无码国产精品9| 一进一出抽搐gif| 色偷偷av男人的天堂| 首页 综合国产 亚洲 丝袜| 国产精品成人无码久久久| 高清不卡毛片免费观看| 国产精品成人一区二区不卡| 激情综合色综合啪啪五月丁香搜索| 思思久久99热只有频精品66| 日日噜噜夜夜狠狠va视频v| 国产又色又爽又黄的| 永久免费观看黄网视频| 四虎国产精品永久地址入口| 体内射精日本视频免费看| 少妇一晚三次一区二区三区| 免费看少妇作爱视频| 久久久亚洲精华液精华液精华液| 动漫精品专区一区二区三区不卡| 永久久久免费人妻精品| 久久精品亚洲中文字幕无码麻豆 | 9l国产精品久久久久麻豆| 让少妇爽到高潮视频| 性欧美大战久久久久久久久| 成年女人18级毛片毛片免费| 国产精品亚洲а∨无码播放| 日本少妇浓毛bbwbbwbbw| 好硬好湿好爽再深一点动态图视频| 日韩精品无码一区二区三区久久久| 亚洲中文字幕无码一区在线| 欧美成va视频网站| 国产亚洲精品一区二三区| 丰满人妻一区二区三区免费视频 | 免费看男女做羞羞的事网站|