在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human ZW10 interactor (ZWINT)

In Stock
  • 中文名稱:
    人ZWINT重組蛋白
  • 貨號:
    CSB-EP527261HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    ZWINT
  • Uniprot No.:
  • 別名:
    Human ZW10 interacting protein 1; HZwint 1; HZwint1; KNTC 2 AP; KNTC2AP; MGC 117174; MGC117174; ZW10 interacting kinetochore protein; ZW10 interacting protein 1; ZW10 interactor; ZW10 interactor; kinetochore protein; ZW10-interacting protein 1; ZWINT 1; ZWINT; Zwint-1; ZWINT_HUMAN; ZWINT1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of BC020979
  • 來源:
    E.coli
  • 分子量:
    58.2kDa
  • 表達區域:
    1-277aa
  • 氨基酸序列
    MEAAETEAEAAALEVLAEVAGILEPVGLQEEAELPAKILVEFVVDSQKKDKLLCSQLQVADFLQNILAQEDTAKGLDPLASEDTSRQKAIAAKEQWKELKATYREHVEAIKIGLTKALTQMEEAQRKRTQLREAFEQLQAKKQMAMEKRRAVQNQWQLQQEKHLQHLAEVSAEVRERKTGTQQELDGVFQKLGNLKQQAEQERDKLQRYQTFLQLLYTLQGKLLFPEAEAEAENLPDDKPQQPTRPQEQSTGDTMGRDPGVSFKAVGLQPAGDVNLP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase.
  • 基因功能參考文獻:
    1. ZW10 interactor was frequently decreased in hepatocellular carcinoma. PMID: 30198401
    2. Our results provide the first evidence that Zwint-1 is required to correct erroneous kinetochore-microtubule attachment and regulate spindle checkpoint function during meiosis. PMID: 26486467
    3. the E3 ubiquitin ligase terf causes protein degradation of ZWINT and negatively regulates cell proliferation PMID: 22023800
    4. These studies identify zwint-1 as a novel AurB substrate required for kinetochore assembly and for proper spindle assembly checkpoint silencing at metaphase PMID: 21775627
    5. hZwint-1 bridges the inner and outer kinetochore: identification of the kinetochore localization domain and the hZw10-interaction domain PMID: 21345172
    6. show that ZW10 interacting protein-1(Zwint-1) is required and is sufficient for kinetochore localization of Zeste White 10 (ZW10) in HeLa cells PMID: 15485811
    7. Stable hZW10 kinetochore residency at prometaphase kinetochores is dependent on its interaction with hZwint-1, and is essential for mitotic checkpoint arrest. PMID: 18268100

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase.
  • 數據庫鏈接:

    HGNC: 13195

    OMIM: 609177

    KEGG: hsa:11130

    STRING: 9606.ENSP00000363055

    UniGene: Hs.591363



主站蜘蛛池模板: 日本老妇人乱xxy| 成人看片黄a免费看| 欧美国产日韩a欧美在线观看| 久久人人97超碰国产公开| 久久久久国色av免费看| 国产精品无码专区av在线播放 | 久久午夜无码鲁丝片秋霞| 国色天香社区视频手机免费| 激情av无码后入| 亚洲日韩久久综合中文字幕 | 300部国产真实乱| 少妇人妻av毛片在线看| 国产99视频精品专区| 欧美大香线蕉线伊人久久| 国产精品av在线| 人妻夜夜爽天天爽三区麻豆av网站 | 国产成人精品综合久久久久| 亚洲第一狼人天堂久久| 人妻无码av中文系列久| 成年美女黄网站色大免费视频| 十八岁污网站在线观看| 大陆国产乱人伦| 五月丁香综合激情六月久久| 成在人线av无码免费| 538prom精品视频在线播放| 久久久久久久曰本精品免费看| 国产色综合天天综合网| 国产亲子乱弄免费视频| 熟女少妇人妻黑人sirbao| 亚洲国产综合在线区尤物| 亚洲最大天堂无码精品区| 久久久久青草线综合超碰| 亚洲精品综合欧美一区二区三区| 日本无遮挡吸乳视频| 欧美猛少妇色xxxxx猛叫| 人妻精品动漫h无码网站| 欧美变态口味重另类在线视频| 偷拍区清纯另类丝袜美腿| 视频在线+欧美十亚洲曰本| 先锋影音人妻啪啪va资源网站| 国产偷窥熟女精品视频大全|