在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human WD repeat and FYVE domain-containing protein 2 (WDFY2)

Recombinant Human WD repeat and FYVE domain-containing protein 2 (WDFY2)

  • 中文名稱：
    人WDFY2重組蛋白
  • 貨號：
    CSB-YP850405HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人WDFY2重組蛋白
  • 貨號：
    CSB-EP850405HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人WDFY2重組蛋白
  • 貨號：
    CSB-EP850405HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人WDFY2重組蛋白
  • 貨號：
    CSB-BP850405HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人WDFY2重組蛋白
  • 貨號：
    CSB-MP850405HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    WDFY2
  • Uniprot No.：
  • 別名：
    PROF; Propeller-FYVE protein; RP11 147H23.1; WD repeat and FYVE domain containing 2; WD repeat and FYVE domain-containing protein 2; WD40 and FYVE domain containing 2; WD40- and FYVE domain-containing protein 2; WDF2; Wdfy2; WDFY2_HUMAN; ZFYVE22; Zinc finger FYVE domain-containing protein 22
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-400
  • 氨基酸序列
    MAAEIQPKPL TRKPILLQRM EGSQEVVNMA VIVPKEEGVI SVSEDRTVRV WLKRDSGQYW PSVYHAMPSP CSCMSFNPET RRLSIGLDNG TISEFILSED YNKMTPVKNY QAHQSRVTMI LFVLELEWVL STGQDKQFAW HCSESGQRLG GYRTSAVASG LQFDVETRHV FIGDHSGQVT ILKLEQENCT LVTTFRGHTG GVTALCWDPV QRVLFSGSSD HSVIMWDIGG RKGTAIELQG HNDRVQALSY AQHTRQLISC GGDGGIVVWN MDVERQETPE WLDSDSCQKC DQPFFWNFKQ MWDSKKIGLR QHHCRKCGKA VCGKCSSKRS SIPLMGFEFE VRVCDSCHEA ITDEERAPTA TFHDSKHNIV HVHFDATRGW LLTSGTDKVI KLWDMTPVVS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2. Positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1. Plays a role in endosomal control of AKT2 signaling; required for insulin-stimulated AKT2 phosphorylation and glucose uptake and insulin-stimulated phosphorylation of AKT2 substrates. Participates in transferrin receptor endocytosis.
  • 基因功能參考文獻：
    1. Our results showed that WDFY2 inhibited cancer cell colony formation and migration via suppressing Akt pathway, making it a potential new therapeutic target in prostate cancer. PMID: 28653900
    2. CDKN2D-WDFY2 fusion could be an important molecular signature for understanding and classifying sub-lineages among heterogeneous high-grade serous ovarian carcinomas. PMID: 24675677
    3. The ProF protein partially co-localizes with EEA1 on vesicular structures and binds to the protein kinases Akt and PKCzeta/lambda (protein kinase Czeta/lambda) via its WD-repeat propeller. PMID: 16792529
    4. WDFY2, the WD40 and FYVE domain containing protein 2, has roles in endocytosis PMID: 16873553
    5. presence of ProF increases the PKCzeta-dependent phosphorylation of VAMP2 in vitro PMID: 17313651

    顯示更多

    收起更多

  • 亞細胞定位：
    Endosome. Early endosome. Cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 20482

    OMIM: 610418

    KEGG: hsa:115825

    STRING: 9606.ENSP00000298125

    UniGene: Hs.208550



主站蜘蛛池模板： 成人a大片在线观看| 偷偷做久久久久网站| 爽爽午夜影视窝窝看片| 男人的天堂2018无码| 少妇高潮喷水久久久久久久久久| 国内精品久久久久久99蜜桃| 欧美成人精品福利视频| 最近中文字幕mv在线视频看| 亚洲国产精品va在线看黑人| 国精品人妻无码一区二区三区喝尿| 四虎永久免费地址入口| 又色又爽又黄的美女裸体网站 | 成人女人看片免费视频放人 | 亚洲欧美日韩久久精品| 久久免费视频精品在线| 自拍偷在线精品自拍偷免费| 情侣黄网站免费看| 亚洲一卡2卡3卡4卡 精品| 无码av在线一本无码| www夜片内射视频在观看视频| 国产一区二区女内射| 国产国产久热这里只有精品| 亚洲色无码专区在线观看| 毛片无码国产| 亚洲精品美女久久久久99| 亚色九九九全国免费视频| 中文无码天天av天天爽| √天堂资源地址中文在线| 亚洲性无码一区二区三区| 日本动漫瀑乳h动漫啪啪免费 | 婷婷久久综合九色综合绿巨人| 少妇人妻挤奶水中文视频毛片| 无码孕妇孕交在线观看| 精品久久久久久无码人妻| 久久性色欲av免费精品观看| 真实国产熟睡乱子伦视频| 艳妇乳肉豪妇荡乳| 亚洲精品一区二区不卡| 鲁鲁网亚洲站内射污| 久久婷婷五月综合色99啪| 免费全部高h视频无码|