在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human WD repeat and FYVE domain-containing protein 2 (WDFY2)

  • 中文名稱:
    人WDFY2重組蛋白
  • 貨號:
    CSB-YP850405HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人WDFY2重組蛋白
  • 貨號:
    CSB-EP850405HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人WDFY2重組蛋白
  • 貨號:
    CSB-EP850405HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人WDFY2重組蛋白
  • 貨號:
    CSB-BP850405HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人WDFY2重組蛋白
  • 貨號:
    CSB-MP850405HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    WDFY2
  • Uniprot No.:
  • 別名:
    PROF; Propeller-FYVE protein; RP11 147H23.1; WD repeat and FYVE domain containing 2; WD repeat and FYVE domain-containing protein 2; WD40 and FYVE domain containing 2; WD40- and FYVE domain-containing protein 2; WDF2; Wdfy2; WDFY2_HUMAN; ZFYVE22; Zinc finger FYVE domain-containing protein 22
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-400
  • 氨基酸序列
    MAAEIQPKPL TRKPILLQRM EGSQEVVNMA VIVPKEEGVI SVSEDRTVRV WLKRDSGQYW PSVYHAMPSP CSCMSFNPET RRLSIGLDNG TISEFILSED YNKMTPVKNY QAHQSRVTMI LFVLELEWVL STGQDKQFAW HCSESGQRLG GYRTSAVASG LQFDVETRHV FIGDHSGQVT ILKLEQENCT LVTTFRGHTG GVTALCWDPV QRVLFSGSSD HSVIMWDIGG RKGTAIELQG HNDRVQALSY AQHTRQLISC GGDGGIVVWN MDVERQETPE WLDSDSCQKC DQPFFWNFKQ MWDSKKIGLR QHHCRKCGKA VCGKCSSKRS SIPLMGFEFE VRVCDSCHEA ITDEERAPTA TFHDSKHNIV HVHFDATRGW LLTSGTDKVI KLWDMTPVVS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2. Positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1. Plays a role in endosomal control of AKT2 signaling; required for insulin-stimulated AKT2 phosphorylation and glucose uptake and insulin-stimulated phosphorylation of AKT2 substrates. Participates in transferrin receptor endocytosis.
  • 基因功能參考文獻:
    1. Our results showed that WDFY2 inhibited cancer cell colony formation and migration via suppressing Akt pathway, making it a potential new therapeutic target in prostate cancer. PMID: 28653900
    2. CDKN2D-WDFY2 fusion could be an important molecular signature for understanding and classifying sub-lineages among heterogeneous high-grade serous ovarian carcinomas. PMID: 24675677
    3. The ProF protein partially co-localizes with EEA1 on vesicular structures and binds to the protein kinases Akt and PKCzeta/lambda (protein kinase Czeta/lambda) via its WD-repeat propeller. PMID: 16792529
    4. WDFY2, the WD40 and FYVE domain containing protein 2, has roles in endocytosis PMID: 16873553
    5. presence of ProF increases the PKCzeta-dependent phosphorylation of VAMP2 in vitro PMID: 17313651

    顯示更多

    收起更多

  • 亞細胞定位:
    Endosome. Early endosome. Cytoplasm.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 20482

    OMIM: 610418

    KEGG: hsa:115825

    STRING: 9606.ENSP00000298125

    UniGene: Hs.208550



主站蜘蛛池模板: 中文字幕无码专区人妻系列| 成人性生交大片免费看vr| 国产成人免费97在线| 又黄又爽又色的免费网站| 人妻丰满熟妇ⅴ无码区a片| 青青草97国产精品免费观看| 亚洲乱亚洲乱妇无码| 欧美综合精品久久久久成人影院 | 狠狠色色综合站| 中文字幕无线码中文字幕免费 | 成人毛片18女人毛片免费| 国产手机在线αⅴ片无码观看| 国产亚洲日韩在线播放更多| 久久99国产精品二区| av片在线播放| 色欲av伊人久久大香线蕉影院| 亚洲337少妇裸体艺术| 俺去啦俺来也五月天| 精品无码人妻一区二区免费蜜桃| 人妻熟女αⅴ一区二区三区| 亚洲欧美日韩综合久久| 国产无遮挡又爽又黄的视频| 影音先锋亚洲成aⅴ人在| k频道国产在线观看| 亚洲成av大片大片在线播放| 日韩久久久久久中文人妻| 欧美成年视频在线观看| 亚洲精品卡2卡3卡4卡5卡区| 男女做爰猛烈啪啪吃奶伸舌头下载| 精品国产av一区二区三区| 亚洲va久久久噜噜噜久久狠狠| 自拍校园亚洲欧美另类| 男女边吃奶边做边爱视频| 婷婷丁香社区| 亚洲第一成年免费网站| 天堂www天堂在线资源| 性xxxx视频播放免费| 忘忧草www中文在线资源| 丁香狠狠色婷婷久久综合| 久久成人a毛片免费观看网站 | 亚洲成在人线av品善网好看|