在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Vesicular acetylcholine transporter (SLC18A3), partial

  • 中文名稱:
    人SLC18A3重組蛋白
  • 貨號:
    CSB-YP613686HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SLC18A3重組蛋白
  • 貨號:
    CSB-EP613686HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SLC18A3重組蛋白
  • 貨號:
    CSB-EP613686HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SLC18A3重組蛋白
  • 貨號:
    CSB-BP613686HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SLC18A3重組蛋白
  • 貨號:
    CSB-MP613686HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    AChR; MGC12716; rVAT; Slc18a3; Solute carrier family 18 (vesicular acetylcholine) member 3; Solute carrier family 18 (vesicular monoamine) member 3; Solute carrier family 18 member 3; VAChT; VACHT_HUMAN; Vesicular acetylcholine transporter
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Involved in acetylcholine transport into synaptic vesicles.
  • 基因功能參考文獻(xiàn):
    1. The results of this study suggest that the Gly360Arg mutant VAChT protein undergoes posttranslational degradation. PMID: 28188302
    2. PCMC expression of ADAM29, FLRT2, and SLC18A3 could be assessed as part of a routine screen to help identify individuals at risk of severe Obstructive sleep apnea in Asian populations PMID: 24732660
    3. Expression of VAChT is increased in neuronal cell lines following upregulation of Lhx8. PMID: 24316404
    4. alpha-Synuclein expression in axons to the distal gut correlates closely with expression of the cholinergic marker, VAChT. PMID: 22821666
    5. Data indicate that siRNA-mediated attenuation of vesicular acetylcholine transporter (VAChT, SLC18A3) reversed the apoptotic activity of vesamicol. PMID: 23222296
    6. Multiple abnormalities with intellectual and developmental disability result from recurrent deletions and reciprocal duplications of 10q11.21q11.23 including CHAT and SLC18A3. PMID: 21948486
    7. overexpressed ChAT enhanced transcription of the CHT1 gene but not the VACHT gene PMID: 21163949
    8. Mutations in the vesicular acetylcholine transporter demonstrate decreased affinity for acetylcholine and vesamicol. PMID: 20831599
    9. The colocalisation of CHT1 immunoreactivity with VAChT immunoreactivity in cholinergic enteric nerves in the human bowel thus suggests that CHT1 represents another marker of cholinergic nerves. PMID: 20490865
    10. Three non-coding SNPs were detected in SLC18A3. None demonstrated any reproducible association with late-onset AD in our samples. PMID: 12759818
    11. An 11.2 kb transgene (named hV11.2) that spanned about 5 kb upstream of the start of VACHT translation down to the first choline acetyltransferase coding exon gave variable expression in the medial habenular nucleus of transgenic mice PMID: 14622097
    12. presence of VAChT in cutaneous nerves and in both epidermal melanocytes and keratinocytes as well as in their nuclei PMID: 16763548
    13. Time-dependent dissociation of bound [3H]vesamicol is biphasic, but equilibrium saturation curves are not. The contrasting phasicity suggests that the pathway to and from the [3H]vesamicol binding site exists in open and at least partially closed states. PMID: 19685929

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Myasthenic syndrome, congenital, 21, presynaptic (CMS21)
  • 亞細(xì)胞定位:
    Membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Major facilitator superfamily, Vesicular transporter family
  • 組織特異性:
    Peripheral and central cholinergic nervous systems.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 10936

    OMIM: 600336

    KEGG: hsa:6572

    STRING: 9606.ENSP00000363229

    UniGene: Hs.654374



主站蜘蛛池模板: 国产精品久久久久影院| 少妇中文字幕乱码亚洲影视| 国产乱子伦一区二区三区| 一二三四视频社区在线播放中国 | 99久久精品费精品国产| 国产jk精品白丝av在线观看| 狠狠色婷婷久久综合频道日韩| 久久/这里只精品99re66| 久久99九九精品久久久久蜜桃| 欧洲精品码一区二区三区免费看| 久久人人爽人人爽人人av东京热| 欧美高潮喷水大叫| 国产精品系列无码专区| 色偷偷色噜噜狠狠成人免费视频| 琪琪女色窝窝777777| 人妻无码久久中文字幕专区| 真实国产熟睡乱子伦视频| 夜夜影院未满十八勿进| 性欧美性另类巨大| 亚洲人成网站18禁止| 午夜不卡av免费| 久久久无码人妻精品一区| 偷窥 亚洲 另类 图片 熟女| 亚欧av无码乱码在线观看性色| 国产又黄又猛又粗又爽的a片动漫 成年女性特黄午夜视频免费看 | 亚洲日韩亚洲另类| 在线播放国产一区二区三区| 黑人上司粗大拔不出来电影| h人成在线看免费视频| 女人被强╳到高潮喷水在线观看| 成人性生交大片免费| 97无码精品综合| 又黄又爽又色视频| 中国国语毛片免费观看视频| 99re久久资源最新地址| 欧美xxxx欧美精品| 国产精品igao视频| 欧美亚洲国产精品久久| 产精品视频在线观看免费 | 国产午夜片无码区在线观看爱情网| 国产午夜鲁丝片av无码|