在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Up-regulator of cell proliferation (URGCP), partial

Recombinant Human Up-regulator of cell proliferation (URGCP), partial

  • 中文名稱：
    人URGCP重組蛋白
  • 貨號：
    CSB-YP837434HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人URGCP重組蛋白
  • 貨號：
    CSB-EP837434HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人URGCP重組蛋白
  • 貨號：
    CSB-EP837434HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人URGCP重組蛋白
  • 貨號：
    CSB-BP837434HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人URGCP重組蛋白
  • 貨號：
    CSB-MP837434HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    URGCP
  • Uniprot No.：
  • 別名：
    FLJ20654; HBV X protein up-regulated gene 4 protein; HBV X protein upregulated gene 4 protein; HBxAg up-regulated gene 4 protein; HBxAg upregulated gene 4 protein; KIAA1507; Up-regulator of cell proliferation; Upregulated gene 4; Upregulator of cell proliferation; URGCP; URGCP_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May be involved in cell cycle progression through the regulation of cyclin D1 expression. May participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. May play an important role in development of gastric cancer.
  • 基因功能參考文獻：
    1. Relationship between URG4/URGCP expression and clinicopathologic characteristics were evaluated and significant results were in various cancer types (review). PMID: 29775749
    2. miR-519 inhibited URG4 expression by directly binding to the 3'UTR of URG4. miR-519 inhibited Cyclin D1 expression and the phosphorylation level of Rb, and increased p21 and p27 expression, confirming miR-519 blocked G1/S transition. PMID: 28315691
    3. Findings indicate that URGCP plays an important role in promoting NSCLC cell invasion and metastasis by enhancing NF-kappaB-activated MMP-9 expression PMID: 26429875
    4. site-directed mutagenesis of potential SP1 binding sites diminished both DNA-protein complexes and SP1-mediated upregulation of URG-4 promoter activity. These findings are valuable for understanding transcriptional regulation of URG4/URGCP that has a pivotal role in cancer progression. PMID: 27766531
    5. FA caused a decrease in the expression of novel gene URG4/URGCP. PMID: 26334619
    6. URG4 overexpression increased the resistance to cisplatin-induced apoptosis in bladder cancer. PMID: 26429874
    7. We presented first mechanisms of TMZ and URG4/URGCP relationship in neuroblastoma cells in this study. As a result, TMZ may be a novel candidate agent for treatment of neuroblastoma as a single or agent or together with other therapeutic agents PMID: 25835972
    8. This study suggests that URG4/URGCP plays an important pro-angiogenic role in HCC via a mechanism linked to activation of the NF-kappaB pathway PMID: 25947641
    9. URG4 overexpression is correlated with cervical cancer progression and poor prognosis in patients with early-stage cervical cancer. PMID: 25427922
    10. Data suggest that neuroblastoma (NB) cell differentiation might associate with peroxisome proliferator-activated receptor alpha (PPARalpha) and URG4/URGCP gene expression profile after retinoic acid (RA) treatment. PMID: 23821302
    11. Rapamycin diminishes URGCP gene expression in DU145 and PC3 cells, but increases expression in LNCaP cells. PMID: 23007575
    12. microRNA profiles were analyzedin HepG2 cells in presence or absence of URG4/URGCP gene using RNA interference. PMID: 23053999
    13. The effects of URGCP/URG4-overexpression or -knockdown on expression of cell cycle regulators and transcriptional activity of FOXO3a, were examined. PMID: 22815774
    14. higher expression of URG4 in our 2 patients suggests that URG4 might be involved in leukemogenesis PMID: 22677619
    15. The data suggest that URG4 may play an important role in the development of hepatocellular carcinoma by partially regulating the expression of cyclin D1. PMID: 20714998
    16. Expression of URG4 in hepatocellular carcinoma is closely related with the expression of HBx. PMID: 20491173
    17. URG4 may be a natural effector of HBxAg that contributes importantly to multistep hepatocarcinogenesis. PMID: 12082552
    18. URG4 plays an important role in the development of human gastric cancer by regulating the expression of cyclin D1. PMID: 17217616
    19. URG4 may play important roles in the development of osteosarcoma, and might be a useful molecular marker for predicting the prognosis of osteosarcoma. PMID: 18972316

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Note=In epithelial cells localized predominantly in the cytoplasm and occasionally in nuclei.
  • 蛋白家族：
    TRAFAC class dynamin-like GTPase superfamily, Very large inducible GTPase (VLIG) family
  • 組織特異性：
    Strongly expressed in hepatitis B virus-infected liver and in HCC cells. Also highly expressed in well-differentiated gastric cancer tissues and various gastric cancer cell lines.
  • 數據庫鏈接：

    HGNC: 30890

    OMIM: 610337

    KEGG: hsa:55665

    STRING: 9606.ENSP00000396918

    UniGene: Hs.663312



主站蜘蛛池模板： 肥臀浪妇太爽了快点再快点 | 美女裸奶100%无遮挡免费网站| 久久久久久久久毛片精品| 国产成人精品视频国产| 国产在线乱子伦一区二区| 国产农村妇女毛片精品久久| 久久久久久人妻一区二区三区| 色综合久久久久无码专区| 成人美女黄网站色大色费全看| 亚洲人成色77777在线观看大战| 亚洲丁香五月天缴情综合| 亚洲人成色4444在线观看| 人妻人人澡人人添人人爽人人玩| 体验区试看120秒啪啪免费| 国产手机在线无码播放视频| 亚洲成色www久久网站| 国产成人无码精品久久久免费| 狠狠色噜噜狠狠狠8888在| 欧美另类精品xxxx| 国产精品原创巨作av| 99久久国产自偷自偷免费一区| 色视频无码专区在线观看| 免免费国产aaaaa片| 日本三级在线观看免费| 国产丝袜无码一区二区视频| 无码综合天天久久综合网| 国产av亚洲精品久久久久久小说| 国产精品99久久99久久久动漫| 亚洲国产av无码精品无广告| 奶真大水真多小荡货av| 国产亚洲久久久久久久| 久久精品人妻无码一区二区三区| 午夜福利在线永久视频| 国产成人无码精品久久涩吧 | 亚洲精品国偷拍自产在线观看蜜桃 | 国产啪精品视频网站免 | 亚洲国产av无码精品| 欧美日韩国产免费一区二区三区 | 日韩 高清 无码 人妻| 曰韩无码二三区中文字幕| 国产久热精品无码激情 |