在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Uncharacterized protein KIAA0226-like (KIAA0226L)

  • 中文名稱:
    人RUBCNL重組蛋白
  • 貨號:
    CSB-YP884481HU
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人RUBCNL重組蛋白
  • 貨號:
    CSB-EP884481HU
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人RUBCNL重組蛋白
  • 貨號:
    CSB-EP884481HU-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人RUBCNL重組蛋白
  • 貨號:
    CSB-BP884481HU
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人RUBCNL重組蛋白
  • 貨號:
    CSB-MP884481HU
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    RUBCNL
  • Uniprot No.:
  • 別名:
    C13orf18; CM018_HUMAN; FLJ21562; FLJ43762 ; KIAA0226 like; KIAA0226L; RP11-247M1.4; Uncharacterized protein C13orf18; Uncharacterized protein KIAA0226-like
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-662
  • 氨基酸序列
    MVSQSTVRQD SPVEPWEGIS DHSGIIDGSP RLLNTDHPPC QLDIRLMRHK AVWINPQDVQ QQPQDLQSQV PAAGNSGTHF VTDAASPSGP SPSCLGDSLA ETTLSEDTTD SVGSASPHGS SEKSSSFSLS STEVHMVRPG YSHRVSLPTS PGILATSPYP ETDSAFFEPS HLTSAADEGA VQVSRRTISS NSFSPEVFVL PVDVEKENAH FYVADMIISA MEKMKCNILS QQQTESWSKE VSGLLGSDQP DSEMTFDTNI KQESGSSTSS YSGYEGCAVL QVSPVTETRT YHDVKEICKC DVDEFVILEL GDFNDITETC SCSCSSSKSV TYEPDFNSAE LLAKELYRVF QKCWILSVVN SQLAGSLSAA GSIVVNEECV RKDFESSMNV VQEIKFKSRI RGTEDWAPPR FQIIFNIHPP LKRDLVVAAQ NFFCAGCGTP VEPKFVKRLR YCEYLGKYFC DCCHSYAESC IPARILMMWD FKKYYVSNFS KQLLDSIWHQ PIFNLLSIGQ SLYAKAKELD RVKEIQEQLF HIKKLLKTCR FANSALKEFE QVPGHLTDEL HLFSLEDLVR IKKGLLAPLL KDILKASLAH VAGCELCQGK GFICEFCQNT TVIFPFQTAT CRRCSACRAC FHKQCFQSSE CPRCARITAR RKLLESVASA AT
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Regulator of autophagy that promotes autophagosome maturation by facilitating the biogenesis of phosphatidylinositol 3-phosphate (PtdIns(3)P) in late steps of autophagy. Acts by antagonizing RUBCN, thereby stimulating phosphatidylinositol 3-kinase activity of the PI3K/PI3KC3 complex. Following anchorage to the autophagosomal SNARE STX17, promotes the recruitment of PI3K/PI3KC3 and HOPS complexes to the autophagosome to regulate the fusion specificity of autophagosomes with late endosomes/lysosomes. Binds phosphoinositides phosphatidylinositol 3-phosphate (PtdIns(3)P), 4-phosphate (PtdIns(4)P) and 5-phosphate (PtdIns(5)P). In addition to its role in autophagy, acts as a regulator of lipid and glycogen homeostasis. May act as a tumor suppressor.
  • 基因功能參考文獻:
    1. Pacer localizes to autophagic structures and positively regulates autophagosome maturation. PMID: 28306502
    2. Re-activation of C13ORF18 led to partial demethylation of the C13ORF18 promoter and decreased repressive histone methylation. PMID: 23522960
    3. Data suggest that the four-gene methylation panel might provide an alternative triage test after primary high-risk papillomavirus (hr-HPV) testing. PMID: 21796628
    4. Methylation of C13orf18 in cervical scrapings is strongly associated with high-grade cervical intraepithelial neoplasia and cervical cancer. PMID: 19843677
  • 亞細胞定位:
    Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein.
  • 組織特異性:
    Expressed weakly in cervical carcinoma cell lines.
  • 數據庫鏈接:

    HGNC: 20420

    KEGG: hsa:80183

    STRING: 9606.ENSP00000374558

    UniGene: Hs.98117



主站蜘蛛池模板: 国产一区二区三区在线电影 | av无码人妻一区二区三区牛牛 | 中文字幕亚洲码在线| 真实国产乱啪福利露脸| 久久亚洲国产精品成人av秋霞| 亚洲另类激情综合偷自拍图片| 国产精品人成电影在线观看| 中文字幕av一区二区三区| 日韩成人一区二区三区在线观看| 97成人碰碰久久人人超级碰oo| 亚洲精品一区二区精华液| 国产一区丝袜高跟鞋| 国产又色又爽又刺激在线观看| 无码人妻av一二区二区三区| 五月天激情电影| 欧美精品成人v高清视频| 中文无码日韩欧av影视| 少妇高潮一区二区三区99| 久久96国产精品久久久| 亚洲第一最快av网站| 熟妇人妻不卡中文字幕| 中国6一12呦女精品| 女人大荫蒂毛茸茸视频| av无码国产在线观看岛国| 亚洲国产成人精品无码区四虎| 色欲香天天天综合网站| 久久综合久久美利坚合众国| 男人的天堂av社区在线| 欧美35页视频在线观看| 成人h动漫精品一区二区无码 | 日韩av午夜在线观看| 婷婷开心激情综合五月天| 国产精品亚洲玖玖玖在线观看| 早起邻居人妻奶罩太松av | 久久亚洲私人国产精品va| 97人妻无码专区| 国产在线精品99一区不卡| 久久精品国产大片免费观看| av一区二区三区人妻少妇| 伊人av超碰伊人久久久| 8x8ⅹ在线永久免费入口|