Recombinant Human Uncharacterized protein C1orf31 (C1orf31)

中文名稱：

Recombinant Human Uncharacterized protein C1orf31(C1orf31)
貨號：

CSB-YP683360HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Human Uncharacterized protein C1orf31(C1orf31)
貨號：

CSB-EP683360HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Human Uncharacterized protein C1orf31(C1orf31)
貨號：

CSB-EP683360HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Human Uncharacterized protein C1orf31(C1orf31)
貨號：

CSB-BP683360HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Human Uncharacterized protein C1orf31(C1orf31)
貨號：

CSB-MP683360HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

COA6
Uniprot No.：

Q5JTJ3
別名：

COA6; C1orf31Cytochrome c oxidase assembly factor 6 homolog
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區(qū)域：

1-125
氨基酸序列

MGPGGPLLSP SRGFLLCKTG WHSNRLLGDC GPHTPVSTAL SFIAVGMAAP SMKERQVCWG ARDEYWKCLD ENLEDASQCK KLRSSFESSC PQQWIKYFDK RRDYLKFKEK FEAGQFEPSE TTAKS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Involved in the maturation of the mitochondrial respiratory chain complex IV subunit MT-CO2/COX2. Thereby, may regulate early steps of complex IV assembly. Mitochondrial respiratory chain complex IV or cytochrome c oxidase is the component of the respiratory chain that catalyzes the transfer of electrons from intermembrane space cytochrome c to molecular oxygen in the matrix and as a consequence contributes to the proton gradient involved in mitochondrial ATP synthesis. May also be required for efficient formation of respiratory supercomplexes comprised of complexes III and IV.
基因功能參考文獻：
1. Results find that COA6 associates with COX2 and is crucial for its maturation and complex IV biogenesis. Also, COA6 interacts with the copper chaperone SCO1 which indicates that COA6 is intrinsically involved in the copper delivery process for COX2. PMID: 26160915
2. Cooperation between COA6 and SCO2 in COX2 maturation during cytochrome c oxidase assembly links two mitochondrial cardiomyopathies. PMID: 25959673
3. Co-purified with C7orf44 (the human ortholog of fungal COX assembly protein) PMID: 22356826
4. COX assembly candidate, ortholog of fungal YMR244C-A PMID: 22356826
5. Strong candidate gene for mitochondrial disease, based on recessive mutations detected in infantile patients PMID: 22277967
6. Observational study of gene-disease association. (HuGE Navigator) PMID: 20877624
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相關疾病：

Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 4 (CEMCOX4)
亞細胞定位：

Mitochondrion intermembrane space.
蛋白家族：

Cytochrome c oxidase subunit 6B family
數(shù)據(jù)庫鏈接：

HGNC: 18025

OMIM: 614772

KEGG: hsa:388753

STRING: 9606.ENSP00000355572

UniGene: Hs.23198