在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Tubulin-folding cofactor B (TBCB)

  • 中文名稱:
    人TBCB重組蛋白
  • 貨號:
    CSB-YP859929HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TBCB重組蛋白
  • 貨號:
    CSB-EP859929HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TBCB重組蛋白
  • 貨號:
    CSB-EP859929HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TBCB重組蛋白
  • 貨號:
    CSB-BP859929HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TBCB重組蛋白
  • 貨號:
    CSB-MP859929HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TBCB
  • Uniprot No.:
  • 別名:
    CG22; CKAPI; Cytoskeleton associated protein 1; Cytoskeleton associated protein CKAPI; Cytoskeleton-associated protein 1; Cytoskeleton-associated protein CKAPI; Tbcb; TBCB_HUMAN; Tubulin folding cofactor B; Tubulin specific chaperone B; Tubulin-folding cofactor B; Tubulin-specific chaperone B
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-244
  • 氨基酸序列
    MEVTGVSAPT VTVFISSSLN TFRSEKRYSR SLTIAEFKCK LELLVGSPAS CMELELYGVD DKFYSKLDQE DALLGSYPVD DGCRIHVIDH SGARLGEYED VSRVEKYTIS QEAYDQRQDT VRSFLKRSKL GRYNEEERAQ QEAEAAQRLA EEKAQASSIP VGSRCEVRAA GQSPRRGTVM YVGLTDFKPG YWIGVRYDEP LGKNDGSVNG KRYFECQAKY GAFVKPAVVT VGDFPEEDYG LDEI
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.
  • 基因功能參考文獻:
    1. Data indicate a microRNA-1825/TBCB/TUBA4A pathway as a putative pathogenic cascade in both familial ALS (fALS) and both sporadic (sALS). PMID: 30030593
    2. the role of the human TBCE and TBCB chaperones in alpha-tubulin-beta-tubulin dissociation, was investigated. PMID: 25908846
    3. results support a role for MAP1 proteins in promoting efficient retrograde trafficking of HIV-1 by stimulating the formation of stable microtubules and mediating the association of HIV-1 cores with microtubules. PMID: 25505242
    4. Overexpression of TBCB leads to the decreased localization of p150 to the microtubule network that might result in a functional modulation of this protein complex. PMID: 22777741
    5. TBCB localizes at spindle and midzone microtubules during mitosis. PMID: 22940919
    6. These findings identified TCoB as the third cytoskeleton protein to be nitrated and suggest a previously undescribed mechanism, whereby growth factor signaling may coordinately integrate nitric oxide signaling in the regulation of microtubule dynamics. PMID: 18048340
    7. TBCB functions as a microtubule density regulator in microglia during activation, and provide an insight into understanding of mechanisms controlling microtubule reorganization during microglial transition between phenotypes. PMID: 19038251
    8. Study demonstrates that, unlike its counterpart TBCE, TBCB only moderately destabilizes microtubules; neither TBCB abundance nor microtubule organization or densities are altered in giant axonal neuropathy mutant fibroblasts. PMID: 19168853

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Cytoplasm, cytoskeleton.
  • 蛋白家族:
    TBCB family
  • 組織特異性:
    Found in most tissues.
  • 數據庫鏈接:

    HGNC: 1989

    OMIM: 601303

    KEGG: hsa:1155

    STRING: 9606.ENSP00000221855

    UniGene: Hs.31053



主站蜘蛛池模板: 秋秋影视午夜福利高清| 国产精品久久久久9999| 国产香蕉尹人视频在线| 成人内射国产免费观看| 国产熟妇高潮呻吟喷水| 亚洲精品久久片久久久久| 精品无码一区在线观看| 色优久久久久综合网鬼色| 天天躁日日躁狠狠躁视频2021| 蜜桃臀无码内射一区二区三区| 性人久久网av| 84pao国产成视频永久免费 | 天天爱天天做久久狼狼| 人妻无码久久一区二区三区免费 | 国产激情久久久久影院老熟女| 亚洲va中文字幕无码久久| 亚洲精品拍拍央视网出文| 2020国产精品午夜福利在线观看 | 国产超碰人人模人人爽人人添| 国产尤物精品视频| 蜜桃av久久久一区二区三区麻豆 | 亚洲人成自拍网站在线观看| 在线播放偷拍一区精品| 天天av天天翘天天综合网色鬼| 欧美日本国产va高清cabal| 丝袜老师办公室里做好紧好爽| 久久无码高潮喷水抽搐| 中文字幕韩国三级理论| 日本免费大黄在线观看| 人妻精品国产一区二区| 日韩人妻无码精品系列| 亚洲色爱图小说专区| 亚洲综合无码久久精品综合| 国产日产欧产精品| 国内精品自线在拍2020不卡| 国产9 9在线 | 欧洲| 国内精品国产三级国产av| 欧美日韩精品suv| 国产亚洲曝欧美不卡精品| 奇米影视777四色米奇影院| 久久97国产超碰青草|