在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Transportin-2 (TNPO2), partial

  • 中文名稱:
    人TNPO2重組蛋白
  • 貨號:
    CSB-YP024021HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TNPO2重組蛋白
  • 貨號:
    CSB-EP024021HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TNPO2重組蛋白
  • 貨號:
    CSB-EP024021HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TNPO2重組蛋白
  • 貨號:
    CSB-BP024021HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TNPO2重組蛋白
  • 貨號:
    CSB-MP024021HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TNPO2
  • Uniprot No.:
  • 別名:
    Importin 3; IPO3; Karyopherin beta 2b, transportin; Karyopherin beta-2b; KPNB2B; Tnpo2; TNPO2_HUMAN; Transportin 2 (importin 3, karyopherin beta 2b); Transportin 2 (Importin 3, karyopherin beta 2b), isoform CRA b; Transportin 2; Transportin-2; TRN2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
  • 基因功能參考文獻:
    1. IPO3 binds NEMO, promotes its nuclear import, and is critical for DNA damage-dependent NF-kappaB activation. PMID: 26060253
    2. Studies indicate potential roles of Tranportin-1 and Transportin-2 beyond protein nuclear import. PMID: 24780099
    3. a role for the nuclear trafficking factor TRN2 (transportin 2) through HuR in cell death PMID: 21646354
    4. Nuclear import of fused in sarcoma (FUS) is dependent on Transportin, and interference with this transport pathway leads to cytoplasmic redistribution and recruitment of fused in sarcoma (FUS) into stress granules. PMID: 20606625
    5. Karyopherin beta 2B participates in mRNA export from the nucleus PMID: 12384575
    6. Transportin-2 mediates nuclear import of HuR protein in vitro PMID: 14981248
    7. The structure of Kap beta 2 (also known as Transportin) bound to one of its substrates, the NLS of hnRNP A1, that we report here explains the mechanism of substrate displacement by Ran GTPase. PMID: 16901787

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Importin beta family, Importin beta-2 subfamily
  • 數據庫鏈接:

    HGNC: 19998

    OMIM: 603002

    KEGG: hsa:30000

    STRING: 9606.ENSP00000407182

    UniGene: Hs.416049



主站蜘蛛池模板: 内射人妻无套中出无码| 又黄又爽又猛的视频免费| 色狠狠久久av五月综合| 久久精品无码一区二区日韩av| 日韩理论午夜无码| 永久免费精品精品永久-夜色| 国产精品鲁鲁鲁| 偷自拍亚洲视频在线观看99| 亚洲高清一区二区三区不卡| 中国精学生妹品射精久久| 40岁成熟女人牲交片20分钟| 亚洲综合无码久久精品综合| 国产欧美久久一区二区三区| 亚洲在av人极品无码| 欧美三級片黃色三級片黃色| 免费观看又色又爽又湿的视频| 特大黑人娇小亚洲女| 亚洲天堂男人影院| 国产精品不卡无码av在线播放| 成人精品动漫一区二区| 亚洲欧洲综合有码无码| 国产精品乱码高清在线观看| 国产成人精品一区二区在线小狼| 四虎国产成人永久精品免费| 一区二区三区波多野结衣在线观看| 久久99亚洲含羞草影院| 性av无码天堂vr专区| 国产电影一区二区三区| 日本夜爽爽一区二区三区| 人与禽交av在线播放| 日韩制服国产精品一区| 久久精品一区二区av999| 国产午夜亚洲精品午夜鲁丝片| 免费人成年激情视频在线观看| 国产亚洲福利在线视频| 亚洲精品伊人久久久大香| 色狠狠成人综合网| 精品无码一区二区三区电影| 亚洲伊人色综合www962| 久久精品亚洲中文无东京热| av午夜福利一片免费看久久|