在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Transportin-2 (TNPO2), partial

  • 中文名稱:
    人TNPO2重組蛋白
  • 貨號:
    CSB-YP024021HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TNPO2重組蛋白
  • 貨號:
    CSB-EP024021HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TNPO2重組蛋白
  • 貨號:
    CSB-EP024021HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TNPO2重組蛋白
  • 貨號:
    CSB-BP024021HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TNPO2重組蛋白
  • 貨號:
    CSB-MP024021HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TNPO2
  • Uniprot No.:
  • 別名:
    Importin 3; IPO3; Karyopherin beta 2b, transportin; Karyopherin beta-2b; KPNB2B; Tnpo2; TNPO2_HUMAN; Transportin 2 (importin 3, karyopherin beta 2b); Transportin 2 (Importin 3, karyopherin beta 2b), isoform CRA b; Transportin 2; Transportin-2; TRN2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
  • 基因功能參考文獻:
    1. IPO3 binds NEMO, promotes its nuclear import, and is critical for DNA damage-dependent NF-kappaB activation. PMID: 26060253
    2. Studies indicate potential roles of Tranportin-1 and Transportin-2 beyond protein nuclear import. PMID: 24780099
    3. a role for the nuclear trafficking factor TRN2 (transportin 2) through HuR in cell death PMID: 21646354
    4. Nuclear import of fused in sarcoma (FUS) is dependent on Transportin, and interference with this transport pathway leads to cytoplasmic redistribution and recruitment of fused in sarcoma (FUS) into stress granules. PMID: 20606625
    5. Karyopherin beta 2B participates in mRNA export from the nucleus PMID: 12384575
    6. Transportin-2 mediates nuclear import of HuR protein in vitro PMID: 14981248
    7. The structure of Kap beta 2 (also known as Transportin) bound to one of its substrates, the NLS of hnRNP A1, that we report here explains the mechanism of substrate displacement by Ran GTPase. PMID: 16901787

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Importin beta family, Importin beta-2 subfamily
  • 數據庫鏈接:

    HGNC: 19998

    OMIM: 603002

    KEGG: hsa:30000

    STRING: 9606.ENSP00000407182

    UniGene: Hs.416049



主站蜘蛛池模板: av无码中文一区二区三区四区| 天天做天天爱夜夜夜爽毛片| 乱码av麻豆丝袜熟女系列| 久久久久久亚洲精品成人| 日韩亚洲国产综合高清| 精品无码久久久久久久动漫| 丰满人妻熟妇乱偷人无码| 中文字幕第一区高清av| 十八禁午夜福利免费网站| 131mm少妇做爰视频| 少妇特黄a一区二区三区| 国产成人无码av在线播放dvd| 成人欧美一区在线视频| 亚洲欧美日韩中文二区| 舌头伸进去搅动好爽视频| 国产精品白丝喷水在线观看| 亚洲精品卡2卡3卡4卡5卡区| 天堂网在线www资源| 亚洲 丝袜 另类 校园 欧美| 亚洲中文字幕无码一区在线 | 凸偷窥中国女人洗澡| 伊人久久精品亚洲午夜| 韩日午夜在线资源一区二区| 无码午夜成人1000部免费视频| 亚洲中文字幕久久精品无码va| av天堂久久精品影音先锋| 久久久久久久久888 | 欧美日本韩国亚洲| 装睡被陌生人摸出水好爽| 国产丝袜在线精品丝袜| 伦埋琪琪久久影院三级| 日本少妇裸体做爰高潮片| 婷婷色爱区综合五月激情| 俄罗斯老熟妇色xxxx| 国产精品熟女高潮视频| 国产免费爽爽视频| 亚洲国产码专区| 久久99亚洲精品久久99果| 免费国产h视频在线观看| 国产精品人妻熟女男人的天堂| 久久精品国产清自在天天线|