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  4. Recombinant Human Transmembrane emp24 domain-containing protein 3 (TMED3), partial

Recombinant Human Transmembrane emp24 domain-containing protein 3 (TMED3), partial

  • 中文名稱：
    人TMED3重組蛋白
  • 貨號：
    CSB-YP897107HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人TMED3重組蛋白
  • 貨號：
    CSB-EP897107HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人TMED3重組蛋白
  • 貨號：
    CSB-EP897107HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人TMED3重組蛋白
  • 貨號：
    CSB-BP897107HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人TMED3重組蛋白
  • 貨號：
    CSB-MP897107HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    TMED3
  • Uniprot No.：
  • 別名：
    C15orf22; Integral type I protein; Membrane protein p24B; p24 family protein gamma 4; p24 family protein gamma-4; P24B; p24g4; p24gamma4; p26; Testis tissue sperm binding protein Li 48e; Tmed3; TMED3_HUMAN; Transmembrane emp24 domain containing protein 3; Transmembrane emp24 domain-containing protein 3; Transmembrane p24 trafficking protein 3; UNQ5357/PRO1078
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network.
  • 基因功能參考文獻：
    1. Study demonstrates that transmembrane p24 trafficking protein 3 (TMED3) promotes hepatocellular carcinoma (HCC) metastasis and is a potential prognostic biomarker in hepatocellular carcinoma. Study propose that TMED3 promotes HCC metastasis through IL-11/STAT3 signaling. PMID: 27901021
    2. This genome-wide screen has identified two novel metastatic suppressors: TMED3 and SOX12, the knockdown of which increases metastatic growth after direct seeding. PMID: 24920608
  • 亞細胞定位：
    Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    EMP24/GP25L family
  • 數據庫鏈接：

    HGNC: 28889

    KEGG: hsa:23423

    STRING: 9606.ENSP00000299705

    UniGene: Hs.513058



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