Recombinant Human Transmembrane domain-containing protein TMIGD3 (TMIGD3 UNQ1931/PRO4406)

中文名稱：
貨號(hào)：

CSB-YP138918HU
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：
貨號(hào)：

CSB-EP138918HU
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：
貨號(hào)：

CSB-EP138918HU-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：
貨號(hào)：

CSB-BP138918HU
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：
貨號(hào)：

CSB-MP138918HU
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

TMIG3
Uniprot No.：

P0DMS9
別名：

Transmembrane domain-containing protein TMIGD3 TMIGD3 UNQ1931/PRO4406
種屬：

Homo sapiens (Human)
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Plays a suppressive role in osteosarcoma malignancy by inhibiting NF-kappa-B activity.
基因功能參考文獻(xiàn)：
1. Protein expression of TMIGD3 and A3AR is lower in human osteosarcoma tissues than normal tissues. Mechanistically, TMIGD3 isoform 1 and A3AR commonly inhibit the PKA-Akt-NF-kappaB axis. PMID: 27886186
亞細(xì)胞定位：

Membrane; Multi-pass membrane protein.
組織特異性：

Expressed in the lung and bone. Expressed at lower levels in osteosarcoma tissues (at protein level).
數(shù)據(jù)庫(kù)鏈接：

HGNC: 51375

KEGG: hsa:57413

STRING: 9606.ENSP00000358730

UniGene: Hs.281342