在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Transforming growth factor beta regulator 1 (TBRG1)

  • 中文名稱:
    人TBRG1重組蛋白
  • 貨號:
    CSB-YP023243HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TBRG1重組蛋白
  • 貨號:
    CSB-EP023243HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TBRG1重組蛋白
  • 貨號:
    CSB-EP023243HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TBRG1重組蛋白
  • 貨號:
    CSB-BP023243HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TBRG1重組蛋白
  • 貨號:
    CSB-MP023243HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TBRG1
  • Uniprot No.:
  • 別名:
    TBRG1; NIAM; Transforming growth factor beta regulator 1; Nuclear interactor of ARF and Mdm2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-411
  • 氨基酸序列
    MSLLDGLASSPRAPLQSSKARMKKLPKKSQNEKYRLKYLRLRKAAKATVFENAAICDEIA RLEEKFLKAKEERRYLLKKLLQLQALTEGEVQAAAPSHSSSLPLTYGVASSVGTIQGAGP ISGPSTGAEEPFGKKTKKEKKEKGKENNKLEVLKKTCKKKKMAGGARKLVQPIALDPSGR PVFPIGLGGLTVYSLGEIITDRPGFHDESAIYPVGYCSTRIYASMKCPDQKCLYTCQIKD GGVQPQFEIVPEDDPQNAIVSSSADACHAELLRTISTTMGKLMPNLLPAGADFFGFSHPA IHNLIQSCPGARKCINYQWVKFDVCKPGDGQLPEGLPENDAAMSFEAFQRQIFDEDQNDP LLPGSLDLPELQPAAFVSSYQPMYLTHEPLVDTHLQHLKSPSQGSPIQSSD
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.
  • 基因功能參考文獻:
    1. In primary B-cell lymphoma NIAM-positive cases have significant lower levels of miR-155 as compared to NIAM-negative cases, suggesting that NIAM is regulated by miR-155 in primary B-cell lymphoma. PMID: 26497687
    2. NIAM regulates 2 critical pathways that control p53 function and are altered in human cancers, implying an important role for NIAM in tumorigenesis. PMID: 24621507
    3. Sructure of a fragment of TBRG1 was shown to encompasses two motifs. The FYRN and FYRC regions each form part of a single folded module (the FYR domain), which adopts a novel alpha + beta fold. PMID: 20506279
    4. novel protein with tumor suppressor-like behaviors and functional links to ARF-MDM2-p53 signaling PMID: 17110379
    5. NIAM is a nuclear interactor of ARF and Mdm2 PMID: 18582208

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    TBRG1 family
  • 組織特異性:
    Widely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver. Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell
  • 數據庫鏈接:

    HGNC: 29551

    OMIM: 610614

    KEGG: hsa:84897

    STRING: 9606.ENSP00000409016

    UniGene: Hs.436410



主站蜘蛛池模板: 日本不卡高字幕在线2019| 少妇高潮流白浆在线观看| 国产免费无码一区二区视频| 国产极品粉嫩馒头一线天av| 精品aⅴ一区二区三区| 精品国产第一福利网站| 日本二区三区欧美亚洲国| 亚洲精品日本久久一区二区三区 | 国产午夜福利精品久久2021| 欧美特级特黄aaaaaa在线看| 天天拍天天看天天做| 亚洲精品成人无码中文毛片| 夜夜欢性恔免费视频| 亚洲人成网站18禁止| 免费无码国产欧美久久18| 国产日韩在线时看高清视频 | 胸大美女又黄的网站| 毛片tv网站无套内射tv网站| 137裸交肉体摄影| 欧美精欧美乱码一二三四区| 少妇被多人c夜夜爽爽| 无码av高潮抽搐流白浆| 7m精品福利视频导航| 久久综合九色综合欧美婷婷| 欲香欲色天天天综合和网| 亚洲精品乱码久久久久久按摩| 加勒比无码一区二区三区| 人妻熟女αⅴ一区二区三区| 亚洲欧美日韩成人综合一区| 免费乱理伦片在线观看| 亚洲国产码专区| 亚洲熟妇无码爱v在线观看| 欧美成人看片一区二区三区尤物| 亚洲午夜私人影院在线观看| 4hu四虎永久在线影院| 精品一区二区三区在线观看| 一区二区三区无码被窝影院| 成人爱做日本视频免费| 国内精品久久久久影院优| 国产精品久久久| 国内揄拍国内精品少妇国语|