在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Transforming growth factor beta regulator 1 (TBRG1)

  • 中文名稱:
    人TBRG1重組蛋白
  • 貨號:
    CSB-YP023243HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TBRG1重組蛋白
  • 貨號:
    CSB-EP023243HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TBRG1重組蛋白
  • 貨號:
    CSB-EP023243HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TBRG1重組蛋白
  • 貨號:
    CSB-BP023243HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TBRG1重組蛋白
  • 貨號:
    CSB-MP023243HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TBRG1
  • Uniprot No.:
  • 別名:
    TBRG1; NIAM; Transforming growth factor beta regulator 1; Nuclear interactor of ARF and Mdm2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-411
  • 氨基酸序列
    MSLLDGLASSPRAPLQSSKARMKKLPKKSQNEKYRLKYLRLRKAAKATVFENAAICDEIA RLEEKFLKAKEERRYLLKKLLQLQALTEGEVQAAAPSHSSSLPLTYGVASSVGTIQGAGP ISGPSTGAEEPFGKKTKKEKKEKGKENNKLEVLKKTCKKKKMAGGARKLVQPIALDPSGR PVFPIGLGGLTVYSLGEIITDRPGFHDESAIYPVGYCSTRIYASMKCPDQKCLYTCQIKD GGVQPQFEIVPEDDPQNAIVSSSADACHAELLRTISTTMGKLMPNLLPAGADFFGFSHPA IHNLIQSCPGARKCINYQWVKFDVCKPGDGQLPEGLPENDAAMSFEAFQRQIFDEDQNDP LLPGSLDLPELQPAAFVSSYQPMYLTHEPLVDTHLQHLKSPSQGSPIQSSD
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.
  • 基因功能參考文獻:
    1. In primary B-cell lymphoma NIAM-positive cases have significant lower levels of miR-155 as compared to NIAM-negative cases, suggesting that NIAM is regulated by miR-155 in primary B-cell lymphoma. PMID: 26497687
    2. NIAM regulates 2 critical pathways that control p53 function and are altered in human cancers, implying an important role for NIAM in tumorigenesis. PMID: 24621507
    3. Sructure of a fragment of TBRG1 was shown to encompasses two motifs. The FYRN and FYRC regions each form part of a single folded module (the FYR domain), which adopts a novel alpha + beta fold. PMID: 20506279
    4. novel protein with tumor suppressor-like behaviors and functional links to ARF-MDM2-p53 signaling PMID: 17110379
    5. NIAM is a nuclear interactor of ARF and Mdm2 PMID: 18582208

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    TBRG1 family
  • 組織特異性:
    Widely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver. Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell
  • 數據庫鏈接:

    HGNC: 29551

    OMIM: 610614

    KEGG: hsa:84897

    STRING: 9606.ENSP00000409016

    UniGene: Hs.436410



主站蜘蛛池模板: 精品无码国产自产拍在线观看蜜| 性xxxx欧美老妇506070| 精品午夜福利无人区乱码一区| 久久综合九色欧美综合狠狠| 亚洲精品色无码av试看| 香港三日本三级少妇三级2021| 中文字幕亚洲一区二区三区| 国模无码视频一区二区三区| 国产精品久久婷婷六月丁香| 香蕉啪视频在线观看视频久| 欧美日韩精品一区二区三区高清视频 | 久久午夜无码鲁丝片午夜精品| 国产乱子经典视频在线观看| 55夜色66夜色国产精品视频| 中文字幕无码日韩中文字幕| 精品人妻av区| 日日摸天天碰中文字幕你懂的| 国产亚洲999精品aa片在线爽| 大胸少妇午夜三级| 四虎影成人精品a片| 免费观看啪啪黄的网站| 人人爽人人添人人超| 一本加勒比波多野结衣| 色老久久精品偷偷鲁| 亚洲精品av一二三区无码| 免费床视频大全叫不停欧美| 色欲色香天天天综合无码www| 青草影院内射中出高潮| 韩国国内大量揄拍精品视频| 欧美丰满熟妇xxxx性ppx人交 | 免费1级a做爰片观看| 国产精品亚洲mnbav网站| 国产毛片久久久久久国产毛片| 亚洲午夜精品a片久久www慈禧| 在线v片免费观看视频| 亚洲精品v日韩精品| 丰满人妻熟妇乱又伦精品视| 国产午夜精品一区二区三区老| 亚洲国产欧美在线成人aaaa| 一本色道无码不卡在线观看| 精品蜜臀av在线天堂|