在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Transcription termination factor 1 (TTF1), partial

  • 中文名稱:
    人TTF1重組蛋白
  • 貨號:
    CSB-EP622994HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    RNA polymerase I termination factor; Transcription termination factor 1; Transcription termination factor I; Transcription termination factor RNA polymerase I; TTF 1; TTF-1; TTF-I; Ttf1; TTF1_HUMAN
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    29.6kDa
  • 表達區域:
    12-232aa
  • 氨基酸序列
    TPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYE
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity.
  • 基因功能參考文獻:
    1. the TTF-1 protein and mRNA are specifically expressed in schwannomas PMID: 29104109
    2. Human TTF-I localizes in the nucleolus and N-terminus (1-224) of hTTF-I which include nucleolus localization sequence and the expression of Human TTF-I 521-732 increased HIV-I production by regulating transactivation of the LTR promoter. PMID: 29555014
    3. These findings collectively suggest that the triple combination of survivin knockdown with ABT-263 and trametinib treatment, may be a potential strategy for the treatment of KRAS-mutant lung adenocarcinoma. Furthermore, our findings indicate that the welldifferentiated type of KRAS-mutant lung tumors depends, at least in part, on TTF1 for growth. PMID: 29658609
    4. TTF-1 expression may serve as a predictive marker to identify lung cancer patients who may benefit from the addition of bevacizumab to platinum doublet therapy. PMID: 30194207
    5. Our results showed that an approach of using only a two-antibody panel (p40 and TTF-1) might help in reduction of diagnostic category of NSCLC-NOS significantly and contribute in saving tissue for future molecular testing PMID: 29168459
    6. Single nucleotide polymorphism in TTF1 gene is associated with Systemic lupus erythematosus PMID: 28246883
    7. Case Report: KRAS mutation-positive bronchial surface epithelium type lung adenocarcinoma with strong expression of TTF-1. PMID: 26823891
    8. Overexpression of Transcription Termination Factor 1 is Associated with Colorectal Cancer PMID: 26036188
    9. Depletion of TTF-I recapitulates the effects of ARF on ribosomal RNA synthesis and is rescued by the introduction of a TTF-I transgene. PMID: 20513429

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Nucleus, nucleolus.
  • 數據庫鏈接:

    HGNC: 12397

    OMIM: 600777

    KEGG: hsa:7270

    STRING: 9606.ENSP00000333920

    UniGene: Hs.54780



主站蜘蛛池模板: 国产1卡二卡3卡四卡乱码视频| 国模小婕私拍鲜嫩玉门| 国内精品久久久久影院老司机| 西欧free性满足hd| 国产精品成人精品久久久| 性xxxx搡xxxxx搡欧美| 亚洲精品卡2卡3卡4卡5卡区 | 亚洲国产中文曰韩丝袜| 欧美写真视频在线观看| 中国丰满熟妇xxxx性| 24小时日本在线www免费的| 免费人成网视频在线观看| 无码色av一二区在线播放| 亚洲熟女乱综合一区二区| 国产精品久久久久影院| 亚洲精品成人网线在线播放va| 噜噜高清欧美内射短视频| 亚洲成a人片在线观看www| 精品无码久久久久国产手机版| 日本欧美一区二区三区高清| 亚洲老熟女av一区二区在线播放| 亚洲人成电影在线观看影院| 亚洲欧美日韩中文播放| 国产欧美日韩久久久久| 97人妻天天摸天天爽天天| 国产欧美va欧美va香蕉在| 一区二区伊人久久大杳蕉| 国产日产欧美最新| 免费精品国产人妻国语| 呻吟国产av久久一区二区| 日日摸日日碰夜夜爽无| 手机福利视频| 六月丁香婷婷色狠狠久久| 国产精品白丝喷浆| 欧美群交射精内射颜射潮喷| 护士脱了内裤让我爽了一夜视频| 12裸体自慰免费观看网站| 欧美黑吊大战白妞| 性人久久久久| 曰本一道本久久88不卡| 无码国产一区二区免费|