在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Thrombospondin-4 (THBS4), partial

Recombinant Human Thrombospondin-4 (THBS4), partial

  • 中文名稱：
    人THBS4重組蛋白
  • 貨號(hào)：
    CSB-YP023490HU
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    人THBS4重組蛋白
  • 貨號(hào)：
    CSB-EP023490HU
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    人THBS4重組蛋白
  • 貨號(hào)：
    CSB-EP023490HU-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人THBS4重組蛋白
  • 貨號(hào)：
    CSB-BP023490HU
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人THBS4重組蛋白
  • 貨號(hào)：
    CSB-MP023490HU
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Thbs4; thrombospondin 4; thrombospondin 4b; Thrombospondin IV; Thrombospondin-4; TSP4; TSP4_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions and is involved in various processes including cellular proliferation, migration, adhesion and attachment, inflammatory response to CNS injury, regulation of vascular inflammation and adaptive responses of the heart to pressure overload and in myocardial function and remodeling. Binds to structural extracellular matrix (ECM) proteins and modulates the ECM in response to tissue damage, contributing to cardioprotective and adaptive ECM remodeling. Plays a role in ER stress response, via its interaction with the activating transcription factor 6 alpha (ATF6) which produces adaptive ER stress response factors and protects myocardium from pressure overload. May contribute to spinal presynaptic hypersensitivity and neuropathic pain states after peripheral nerve injury. May play a role in regulating protective astrogenesis from the subventricular zone (SVZ) niche after injury in a NOTCH1-dependent manner.
  • 基因功能參考文獻(xiàn)：
    1. establish a novel molecular mechanism by which miR-148a-3p upregulates Tsp-4 expression in tenocytes to promote angiogenesis by targeting KLF6, which could be helpful for the treatment of tendinopathy in the future PMID: 29807011
    2. Findings indicate that loss of miR-142 results in the over-expression of THBS4, which enhances HCC migration and vascular invasion. PMID: 28177895
    3. the present study demonstrates that THBS4 and lncRNA-THBS4-003 serve a significant role in PCa proliferation and migration via the MMP-9 and p38 MAPK signaling pathway. PMID: 27357608
    4. The THBS4 A387P polymorphism was associated with coronary artery disease in American population. PMID: 25976449
    5. Tsp4 functions as an ECM scaffold at myotendinous junctions, with potential therapeutic uses in tendon strengthening and repair PMID: 24941943
    6. THBS4 expression in breast cancer-associated extracellular matrix contributes to the activated stromal response exhibited during tumour progression PMID: 23942617
    7. the balancing selection target in THBS4 is likely represented by one or more variants that regulate tissue-specific and sex-specific gene expression PMID: 23420636
    8. The results of thid study suggested that injury-induced spinal TSP4 may contribute to spinal presynaptic hypersensitivity and neuropathic pain states. PMID: 22745497
    9. genetic polymorphism predicts cardiovascular risk in postinfarction patients with high HDL cholesterol and C-reactive protein levels PMID: 22011848
    10. Identify THBS4 as a powerful marker for diffuse-type gastric adenocarcinomas and to provide an initial characterization of its expression in the course of this disease. PMID: 21701537
    11. High THBS4 methylation resulting in inactivation of the gene is associated with colorectal cancer. PMID: 20846368
    12. thrombospondin-4 C-terminal peptide has a role in stimulating erythroid cell proliferation PMID: 15474480
    13. Promoter hypermethylation of thrombospondin 4 is associated with cutaneous T-cell lymphoma PMID: 15897551
    14. Homozygosity for thrombospondin-4 1186C (Arg387Pro) variant is a risk factor for myocardial infarction especially in older women. PMID: 16923428
    15. The functional analysis of the rat counterpart. PMID: 7490284

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Endoplasmic reticulum. Sarcoplasmic reticulum. Secreted. Secreted, extracellular space. Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Thrombospondin family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 11788

    OMIM: 600715

    KEGG: hsa:7060

    STRING: 9606.ENSP00000339730

    UniGene: Hs.211426



主站蜘蛛池模板： 色多多www视频在线观看免费| 亚洲色欲色欲天天天www| 内射视频←www夜| 亚洲高清一区二区三区不卡| 国产百合互慰吃奶互揉视频| 无码国产成人午夜在线观看 | 无码国模大尺度视频在线观看| 亚洲hdmi高清线| 国产98在线 | 免费、| 非洲人与性动交ccoo| 国产又爽又黄无码无遮挡在线观看 | 日产精品99久久久久久| 曰批视频免费30分钟成人| 久久av无码αv高潮αv喷吹| 国产综合在线观看| 久久精品第一国产久精国产宅男66| 国产精品无码久久综合网| 国产精品无码嫩草地址更新| 精品综合久久久久久888蜜芽| 精品人妻少妇一区二区三区不卡| 偷偷要色偷偷中文无码| 综合欧美亚洲日本一区| 国产伦精品一区二区三区免.费| 精品久久久久中文字幕一区| 亚洲最大av无码国产| 欧美性色黄大片www喷水| 亚洲制服丝袜自拍中文字幕| 女厕厕露p撒尿八个少妇| 国产乱人伦偷精品视频| 亚洲这里只有久热精品伊人| 日本人妻中文字幕乱码系列| 美女露出粉嫩小奶头在视频18禁| 国产成人免费永久在线平台| 欧美叉叉叉bbb网站| 伊人久久丁香色婷婷啪啪| 国产成人av在线影院无毒| 国产日产韩国精品视频| 成年女人色毛片| 婷婷俺也去俺也去官网| 亚洲另类色区欧美日韩图片| 人妻去按摩店被黑人按中出|