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Recombinant Human Thioredoxin-like protein 4B (TXNL4B)

  • 中文名稱:
    人TXNL4B重組蛋白
  • 貨號:
    CSB-EP868342HU
  • 規(guī)格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    TXNL4B
  • Uniprot No.:
  • 別名:
    AI595343; D530025J19Rik; Dim1 like protein; Dim1-like protein; DIM2; DLP; FLJ20511; MGC109322; RGD1305127; Thioredoxin like 4B; Thioredoxin like protein 4B; Thioredoxin-like protein 4B; TXN4B_HUMAN; Txnl4b
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    44.0kDa
  • 表達(dá)區(qū)域:
    1-149aa
  • 氨基酸序列
    MSFLLPKLTSKKEVDQAIKSTAEKVLVLRFGRDEDPVCLQLDDILSKTSSDLSKMAAIYLVDVDQTAVYTQYFDISYIPSTVFFFNGQHMKVDYGSPDHTKFVGSFKTKQDFIDLIEVIYRGAMRGKLIVQSPIDPKNIPKYDLLYQDI
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal GST-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    Essential role in pre-mRNA splicing. Required in cell cycle progression for S/G(2) transition.
  • 基因功能參考文獻(xiàn):
    1. A crystal structure of TXNL4B was determined at 1.33 A resolution and refined to an Rwork of 0.13 and an Rfree of 0.18 with one native dimer in the asymmetric unit. PMID: 23519793
    2. DLP is implicated in not only cell cycle progression but also in a more specific molecular process such as pre-mRNA splicing PMID: 15161931
    3. crystal structure; in contrast to hDim1, hDim2 forms stable homodimers PMID: 16142897
    4. The human gene coding for the spliceosomal protein thioredoxin-like 4B (TXNL4B) was overexpressed in Escherichia coli and the encoded protein was purified and crystallized. PMID: 16511018
  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    DIM1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 26041

    OMIM: 617722

    KEGG: hsa:54957

    STRING: 9606.ENSP00000268483

    UniGene: Hs.134406



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