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  4. Recombinant Human Teneurin-2 (ODZ2), partial

Recombinant Human Teneurin-2 (ODZ2), partial

  • 中文名稱：
    人TENM2重組蛋白
  • 貨號：
    CSB-YP885724HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人TENM2重組蛋白
  • 貨號：
    CSB-EP885724HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人TENM2重組蛋白
  • 貨號：
    CSB-EP885724HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人TENM2重組蛋白
  • 貨號：
    CSB-BP885724HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人TENM2重組蛋白
  • 貨號：
    CSB-MP885724HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    TENM2
  • Uniprot No.：
  • 別名：
    TENM2; KIAA1127; ODZ2; TNM2; Teneurin-2; Ten-2; Protein Odd Oz/ten-m homolog 2; Tenascin-M2; Ten-m2; Teneurin transmembrane protein 2) [Cleaved into: Ten-2; soluble form; Ten-2 intracellular domain; Ten-2 ICD)]
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes the formation of filopodia and enlarged growth cone in neuronal cells. Induces homophilic cell-cell adhesion. May function as a cellular signal transducer.; Acts as a ligand of the ADGRL1 receptor. Mediates axon guidance and heterophilic cell-cell adhesion.; Induces gene transcription inhibition.
  • 基因功能參考文獻：
    1. TENM2 knockdown induces both UCP1 mRNA and protein expression upon adipogenic differentiation without affecting mitochondrial mass. PMID: 28088466
    2. intracellular domain of teneurin-2 has a nuclear function and role in repressing zic-1-mediated transcription PMID: 12783990
    3. Gene rearrangements of ODZ2 is associated with mucosa-associated lymphoid tissue lymphoma. PMID: 18927281
  • 亞細胞定位：
    Cell membrane; Single-pass membrane protein. Endoplasmic reticulum. Golgi apparatus. Cell junction, synapse. Cell projection, dendritic spine. Cell projection, filopodium. Cell projection, growth cone. Cell junction, synapse, postsynaptic cell membrane; Single-pass membrane protein. Cell junction, synapse, synaptosome.; [Isoform 2]: Cell membrane. Note=Colocalizes with ADGRL1 across intercellular junctions.; [Ten-2 intracellular domain]: Nucleus, PML body.
  • 蛋白家族：
    Tenascin family, Teneurin subfamily
  • 組織特異性：
    Highly expressed in heart, followed by brain, liver, kidney and fetal brain and weakly expressed in lung and testis. No expression was detected in skeletal muscle, pancreas, spleen, ovary and fetal liver.
  • 數據庫鏈接：

    HGNC: 29943

    OMIM: 610119

    KEGG: hsa:57451

    STRING: 9606.ENSP00000429430

    UniGene: Hs.631957



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