在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Telomerase protein component 1 (TEP1), partial

  • 中文名稱:
    人TEP1重組蛋白
  • 貨號:
    CSB-EP859117HU
  • 規(guī)格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    TEP1
  • Uniprot No.:
  • 別名:
    TEP1; TLP1; TP1; Telomerase protein component 1; Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homolog
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    26.8kDa
  • 表達(dá)區(qū)域:
    2392-2594aa
  • 氨基酸序列
    LKLLCMKPGDAPSEIWSSYTENPMILSTHKEYGIFVLQPKDPGVLSFLRQKESGEFEERLNFDINLENPSRTLISITQAKPESESSFLCASSDGILWNLAKCSPEGEWTTGNMWQKKANTPETQTPGTDPSTCRESDASMDSDASMDSEPTPHLKTRQRRKIHSGSVTALHVLPELLVTASKDRDVKLWERPSMQLLGLFRCE
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC.
  • 基因功能參考文獻(xiàn):
    1. The current results suggested that genetic variants at TEP1 SNPs rs1760893 and rs1713423 may be associated significantly with increased risk of stomach cancer. PMID: 27305982
    2. TEP1 Polymorphisms are not associated with Hepatocellular Carcinoma in Thai Patients with Chronic Hepatitis B Virus Infection. PMID: 27221889
    3. These data suggest that genetic variations in the TEP1 gene may be biomarkers for risk of PCa and BCR after RP. PMID: 26238235
    4. 8 common SNPs in telomerase reverse transcriptase (TERT) and telomerase-associated protein 1 (TEP1) were genotyped. PMID: 24269974
    5. the protein levels of MVP, TEP1 and vPARP are actually increased in the highergrade tumors suggesting existence of post-transcriptional regulation of vault component production. PMID: 23739867
    6. TP1 expression did not change after cisplatin exposure for 72 hours. PMID: 11942411
    7. TEP1, hTR, hsp90, p23, and dyskerin remained at high and unchanged levels throughout up- or down regulation of telomerase activity. PMID: 12135483
    8. expression of telomerase activity and its subunit level in pancreatic carcinoma significantly correlate with the clinical stage of pancreatic carcinoma PMID: 12918126
    9. Telomerase activity and hTERT, TP-1 mRNA expression are up-regulated in esophageal squamous cell carcinoma PMID: 14606063
    10. The epithelial expression of TP-1 is elevated in mildly active UC. PMID: 18938767
    11. TEP1, TOPOIIalpha, and HSP90 interact directly with BLM in vitro and modulate its helicase activity on telomere-like DNA substrates but not on non-telomeric substrates. PMID: 19329795

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus. Chromosome, telomere.
  • 組織特異性:
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 11726

    OMIM: 601686

    KEGG: hsa:7011

    STRING: 9606.ENSP00000262715

    UniGene: Hs.508835



主站蜘蛛池模板: 亚洲色婷婷婷婷五月基地| 国产不卡视频一区二区三区| 欧美私人情侣网站| 粗壮挺进人妻水蜜桃成熟漫画| 亚洲r成人av久久人人爽| 特黄特色大片免费播放器图片| 中国国语毛片免费观看视频| 国产薄丝脚交视频在线观看| 99久久九九社区精品| 欧美成人国产精品高潮| 国产精品久久久久久爽爽爽| 亚洲国产精品国自产拍电影| 国产男女免费完整视频在线| 亚洲熟妇无码另类久久久| 插插无码视频大全不卡网站| 狠狠色综合网久久久久久| 亚洲最大av一区二区三区| 手机在线亚洲国产精品| 国产在线视频一区二区三区| 国产精品污www在线观看| 久久无码潮喷a片无码高潮| 熟妇激情内射com| 日韩少妇内射免费播放18禁裸乳 | 亚洲日韩片无码中文字幕| 亚洲a片成人无码久久精品色欲| 国外亚洲成av人片在线观看| 久久精品a亚洲国产v高清不卡| 四虎国产精品一区二区| 色综合久久无码中文字幕 | 日韩 高清 无码 人妻| 成人午夜福利视频| 亚洲成av人综合在线观看| 国产情侣真实54分钟在线| 亚洲人成人无码网www电影首页| 日本真人做爰免费视频120秒| 无码国内精品人妻少妇| 亚洲午夜无码极品久久| 中文字字幕在线精品乱码| 亚洲中文无码av在线| 成人午夜国产内射主播| 狠狠色老熟妇老熟女|