在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Tectonic-1 (TCTN1)

Recombinant Human Tectonic-1 (TCTN1)

  • 中文名稱：
    人TCTN1重組蛋白
  • 貨號：
    CSB-YP642681HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人TCTN1重組蛋白
  • 貨號：
    CSB-EP642681HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人TCTN1重組蛋白
  • 貨號：
    CSB-EP642681HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人TCTN1重組蛋白
  • 貨號：
    CSB-BP642681HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人TCTN1重組蛋白
  • 貨號：
    CSB-MP642681HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    TCTN1
  • Uniprot No.：
  • 別名：
    JBTS13; TCTN1; TECT1; TECT1_HUMAN; Tectonic family member 1; Tectonic-1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    23-587
  • 氨基酸序列
    QTDATPAV TTEGLNSTEA ALATFGTFPS TRPPGTPRAP GPSSGPRPTP VTDVAVLCVC DLSPAQCDIN CCCDPDCSSV DFSVFSACSV PVVTGDSQFC SQKAVIYSLN FTANPPQRVF ELVDQINPSI FCIHITNYKP ALSFINPEVP DENNFDTLMK TSDGFTLNAE SYVSFTTKLD IPTAAKYEYG VPLQTSDSFL RFPSSLTSSL CTDNNPAAFL VNQAVKCTRK INLEQCEEIE ALSMAFYSSP EILRVPDSRK KVPITVQSIV IQSLNKTLTR REDTDVLQPT LVNAGHFSLC VNVVLEVKYS LTYTDAGEVT KADLSFVLGT VSSVVVPLQQ KFEIHFLQEN TQPVPLSGNP GYVVGLPLAA GFQPHKGSGI IQTTNRYGQL TILHSTTEQD CLALEGVRTP VLFGYTMQSG CKLRLTGALP CQLVAQKVKS LLWGQGFPDY VAPFGNSQAQ DMLDWVPIHF ITQSFNRKDS CQLPGALVIE VKWTKYGSLL NPQAKIVNVT ANLISSSFPE ANSGNERTIL ISTAVTFVDV SAPAEAGFRA PPAINARLPF NFFFPFV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Regulator of Hedgehog (Hh), required for both activation and inhibition of the Hh pathway in the patterning of the neural tube. During neural tube development, it is required for formation of the most ventral cell types and for full Hh pathway activation. Functions in Hh signal transduction to fully activate the pathway in the presence of high Hh levels and to repress the pathway in the absence of Hh signals. Modulates Hh signal transduction downstream of SMO and RAB23.
  • 基因功能參考文獻：
    1. we describe the phenotype of a patient with Varadi syndrome who is homozygous for a previously reported mutation in TCTN1 (NM_001082538.2:c.342-2A>G, p.Gly115Lysfs*8) and suggest that allelic disorders linked to TCTN1 include Varadi syndrome, in addition to Joubert syndrome and Meckel-Gruber syndrome. PMID: 28631893
    2. Flow cytometry analysis showed that depletion of TCTN1 could cause cell cycle arrest at the G2/M phase. This indicates that TCTN1 may be crucial for CRC cell growth. PMID: 28123172
    3. High TCTN1 expression is associated with Pancreatic Cancer. PMID: 26844847
    4. These findings confirmed the direct association between the TCTN1 gene and prostate cancer growth in vitro. PMID: 26310786
    5. These data suggest TCTN1 is essential for glioma cell viability, and dysregulation of TCTN1 may play a key role in glioma tumorigenesis. PMID: 25737023
    6. TCTN1 may serve as a novel prognostic factor and a potential therapeutic target for glioblastoma. PMID: 25304031
    7. Mutations in Tctn1 is associated with ciliopathies. PMID: 21725307

    顯示更多

    收起更多

  • 相關疾病：
    Joubert syndrome 13 (JBTS13)
  • 亞細胞定位：
    Cytoplasm, cytoskeleton, cilium basal body. Secreted.
  • 蛋白家族：
    Tectonic family
  • 數據庫鏈接：

    HGNC: 26113

    OMIM: 609863

    KEGG: hsa:79600

    STRING: 9606.ENSP00000380779

    UniGene: Hs.211511



主站蜘蛛池模板： 亚洲乱亚洲乱少妇无码99p| 国产在线视频主播区| 国内精品久久久久久久小说| 国产精品久久久一区二区三区| 无码国产精品一区二区免费i6 | 水蜜桃av无码| 亚洲日韩高清在线亚洲专区| 成人亚洲欧美日韩在线观看| 男女猛烈无遮挡免费视频在线观看| 国产成人a∨激情视频厨房| 国产精品嫩草影院av| 国产亚洲精品a在线| 香蕉久久国产超碰青草| 亚洲日本一区二区三区在线| 国产sm调教折磨视频| 亚洲高清乱码午夜电影网| 好日子在线观看视频大全免费动漫| 少妇高潮惨叫久久久久电影| 国模gogo无码人体啪啪| 999zyz玖玖资源站永久| 亚洲中文字幕永久在线不卡| 国精产品48x国精产品| 亚洲丁香婷婷久久一区二区| 真人与拘做受免费视频| 无码精品人妻一区二区三区人妻斩| 日本少妇xxx做受| 成人亚洲国产精品一区不卡| 在线看片人成视频免费无遮挡| 国产精品亚洲一区二区三区| 欧美综合乱图图区乱图图区| 欧美日韩精品一区二区在线观看| 亚洲中文字幕在线观看| 国内久久婷婷五月综合色| 丰满的少妇被猛烈进入白浆| 精品无人区无码乱码毛片国产| 国产精品久久福利网站| 一本大道无码av天堂| 99热在线观看| 成人aa免费视频在线播放| 香蕉啪视频在线观看视频久| 漂亮人妻被黑人久久精品|