在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Taste receptor type 2 member 4 (TAS2R4), partial

  • 中文名稱:
    人TAS2R4重組蛋白
  • 貨號:
    CSB-YP882148HU1
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TAS2R4重組蛋白
  • 貨號:
    CSB-EP882148HU1
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TAS2R4重組蛋白
  • 貨號:
    CSB-EP882148HU1-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TAS2R4重組蛋白
  • 貨號:
    CSB-BP882148HU1
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TAS2R4重組蛋白
  • 貨號:
    CSB-MP882148HU1
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    TAS2R4; Taste receptor type 2 member 4; T2R4
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.
  • 基因功能參考文獻:
    1. demonstrate that Lys117, an important CRAC residue, is crucial in the reported cholesterol sensitivity of T2R4. Interestingly, cholesterol sensitivity of T2R4 was observed at quinine concentrations in the lower mM range. PMID: 27288892
    2. This study is the first to show an inhibitory downstream action of a T2R4 agonist on Rac1 function. PMID: 27873143
    3. Data indicate that KLK/R motif in C-terminus performs functional role in bitter taste receptor T2R4 signaling. PMID: 25858111
    4. The antagonist ability of ABA was tested using another T2R4 agonist, yohimbine. Our results suggest that ABA does not inhibit yohimbine-induced T2R4 activity. PMID: 25844797
    5. Data indicate that the itter blockers and agonists share the same orthosteric site in bitter taste receptor T2R4. PMID: 25059668
    6. these results show that rhodopsin N-terminal 33 amino acids enhance expression of T2R4 by 2.5-fold and do not cause perturbations in the receptor structure. PMID: 23159609
    7. This study demonistrated that human TAS2R4 play the role of food preference behavior. PMID: 22794107

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
  • 蛋白家族:
    G-protein coupled receptor T2R family
  • 組織特異性:
    Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Expressed on airway ciliated epithelium.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 14911

    OMIM: 604869

    KEGG: hsa:50832

    STRING: 9606.ENSP00000247881

    UniGene: Hs.735690



主站蜘蛛池模板: 狠狠久久精品中文字幕无码| 国产精品成人国产乱| 天堂mv在线mv免费mv香蕉| 国产欧美综合在线观看第十页| 免费国产高清在线精品一区| 农民人伦一区二区三区| 西西444www无码大胆| 国产精品一国产精品一k频道 | 中文字幕日韩精品亚洲一区| 色欲来吧来吧天天综合网| 日产精品久久久久久久蜜臀| 影音先锋人妻啪啪av资源网站| 香港日本三级亚洲三级 | 大帝av在线一区二区三区| 国产成人免费高清直播| 四虎永久在线精品免费网站 | 亚洲精品一区二区三区新线路 | 成人性生交大片免费看vr| 久久亚洲精品成人av二次元| 国产亚洲精品久久一区二区| 亚洲高清最新av网站| 香蕉免费一区二区三区在| 国产av亚洲aⅴ一区二区| 国内嫩模私拍精品视频| 亚洲三区在线观看无套内射| 国产免费人成视频尤勿视频| 在线无码av一区二区三区| 国产啪精品视频网站| 成人网站免费观看| 性欧美丰满熟妇xxxx性5| 成人国内精品久久久久一区| 人妻有码av中文字幕久久琪| 99精品热这里只有精品| 五 月 丁 香 综合中文| 无码日韩人妻精品久久蜜桃| 99热这里只就有精品22| 亚洲伊人情人综合网站| 久久精品国产精品亚洲艾草网| 亚洲成在人线av无码| 天天爽天天狠久久久综合麻豆 | 久久天天躁夜夜躁狠狠85麻豆|