在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Taste receptor type 2 member 4 (TAS2R4), partial

  • 中文名稱:
    人TAS2R4重組蛋白
  • 貨號:
    CSB-YP882148HU1
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TAS2R4重組蛋白
  • 貨號:
    CSB-EP882148HU1
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人TAS2R4重組蛋白
  • 貨號:
    CSB-EP882148HU1-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TAS2R4重組蛋白
  • 貨號:
    CSB-BP882148HU1
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TAS2R4重組蛋白
  • 貨號:
    CSB-MP882148HU1
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    TAS2R4; Taste receptor type 2 member 4; T2R4
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.
  • 基因功能參考文獻:
    1. demonstrate that Lys117, an important CRAC residue, is crucial in the reported cholesterol sensitivity of T2R4. Interestingly, cholesterol sensitivity of T2R4 was observed at quinine concentrations in the lower mM range. PMID: 27288892
    2. This study is the first to show an inhibitory downstream action of a T2R4 agonist on Rac1 function. PMID: 27873143
    3. Data indicate that KLK/R motif in C-terminus performs functional role in bitter taste receptor T2R4 signaling. PMID: 25858111
    4. The antagonist ability of ABA was tested using another T2R4 agonist, yohimbine. Our results suggest that ABA does not inhibit yohimbine-induced T2R4 activity. PMID: 25844797
    5. Data indicate that the itter blockers and agonists share the same orthosteric site in bitter taste receptor T2R4. PMID: 25059668
    6. these results show that rhodopsin N-terminal 33 amino acids enhance expression of T2R4 by 2.5-fold and do not cause perturbations in the receptor structure. PMID: 23159609
    7. This study demonistrated that human TAS2R4 play the role of food preference behavior. PMID: 22794107

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Multi-pass membrane protein. Cell projection, cilium membrane. Note=In airway epithelial cells, localizes to motile cilia.
  • 蛋白家族:
    G-protein coupled receptor T2R family
  • 組織特異性:
    Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Expressed on airway ciliated epithelium.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 14911

    OMIM: 604869

    KEGG: hsa:50832

    STRING: 9606.ENSP00000247881

    UniGene: Hs.735690



主站蜘蛛池模板: 丰满的少妇愉情hd高清果冻传媒| 国内精品伊人久久久久影院对白| 日日摸日日碰夜夜爽无码| 亚洲aⅴ无码专区在线观看q| 久久久久成人网站| 欧美不卡高清一区二区三区| 国产sm鞭打折磨调教视频| 综合偷自拍亚洲乱中文字幕 | 亚洲伊人久久精品影院| 欧美牲交a欧美牲交aⅴ久久| 强行交换配乱婬bd| 国内精品乱码卡一卡2卡麻豆| 国产人成午夜免电影费观看| 一边摸一边叫床一边爽av| 国产精品一区二区av在线观看| 国产精品久久久久久无码| 午夜婷婷精品午夜无码a片影院| 又色又爽又黄还免费毛片96下载 | 国产专区国产av| 肉大捧一进一出免费视频| 国产精品美女久久久浪潮av | 4480yy私人精品国产| 久久综合婷婷丁香五月中文字幕| 成年性生交大片免费看| 欧美亅性猛交内射| 亚洲国产制服丝袜先锋| 成人影院yy111111在线观看| 少妇高潮喷潮久久久影院| 亚洲国产成人av网站| 2019一級特黃色毛片免費看| 人妻色综合网站| 亚洲色自偷自拍另类小说| 色又黄又爽18禁免费网站| 中国极品少妇videossexhd| 国产精品538一区二区在线| 亚洲日本在线在线看片| 亚洲久久久久久中文字幕| 国产乱子伦一区二区三区| 亚洲国产v高清在线观看| 男人狂躁进女人下面免费视频| 日韩网红少妇无码视频香港 |