在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human TP53-regulated inhibitor of apoptosis 1 (TRIAP1)

  • 中文名稱:
    人TRIAP1重組蛋白
  • 貨號:
    CSB-EP024443HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    TRIAP1
  • Uniprot No.:
  • 別名:
    p53-inducible cell-survival factor; p53CSV; Protein 15E1.1; TP53-regulated inhibitor of apoptosis 1; TRIA1_HUMAN; Triap1; WF 1; WF1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    E.coli
  • 分子量:
    35.8kDa
  • 表達區域:
    1-76aa
  • 氨基酸序列
    MNSVGEACTDMKREYDQCFNRWFAEKFLKGDSSGDPCTDLFKRYQQCVQKAIKEKEIPIEGLEFMGHGKEKPENSS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal GST-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes (in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis.
  • 基因功能參考文獻:
    1. TRIAP1 is regulated by miR-320b and has a role in progression in nasopharyngeal carcinoma PMID: 27428374
    2. Results describe the upregulation of TRIAP1 in drugresistant breast cancer cells. Its experimental modulation changed breast tumor cells sensitivity to doxorubicin, thus confirming its role in drug resistance. PMID: 25998939
    3. TRIAP1 is Conserved Specific Coregulators of the p21:PUMA Expression Ratio. PMID: 23684607
    4. Under specific conditions of stress, p53 regulates transcription of p53CSV and that p53CSV is one of the important players in the p53-mediated cell survival. PMID: 15735003
    5. Upregulated in at least 50% of multiple myeloma cases tested. PMID: 19171422
    6. HSPC132 is p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway PMID: 15735003

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion. Mitochondrion intermembrane space.
  • 蛋白家族:
    TRIAP1/MDM35 family
  • 數據庫鏈接:

    HGNC: 26937

    OMIM: 614943

    KEGG: hsa:51499

    STRING: 9606.ENSP00000449795

    UniGene: Hs.69499



主站蜘蛛池模板: 性xxxx18免费观看视频| 国产麻无矿码直接观看| 国产午夜亚洲精品国产成人小说| 中文在线最新版天堂| 久久精品无码免费不卡| 亚洲乱亚洲乱妇无码麻豆 | 婷婷综合缴情亚洲狠狠小说| 欧美综合自拍亚洲综合图| 国产av麻豆mag剧集| 午夜精品久久久久久久四虎| 中文字幕人妻丝袜成熟乱 | 国产成人无码a区在线观看导航| 无码中文字幕波多野结衣| 日本一卡二卡3卡四卡网站精品| 久久综合久久综合九色| 国产av天堂无码一区二区三区 | 韩国久久久久久级做爰片| 亚洲午夜福利精品无码不卡| 国产成人精品无码免费看夜聊软件 | 国产免费高清69式视频在线观看| 秋霞特色aa大片| 久久久久无码中| 午夜无码一区二区三区在线| 精品人妻二区中文字幕| 髙清国产性猛交xxxand| 黑人上司粗大拔不出来电影| 亚洲精品无码专区在线| 国产成人av综合色| 中文字幕在线观看| 国产成人av在线播放影院| 爱久久av一区二区三区| 强奷乱码中文字幕熟女导航| 成人午夜高潮免费视频在线观看 | 女上男下啪啪激烈高潮无遮盖| 欧美饥渴熟妇高潮喷水水| 少妇人妻精品一区二区| 香蕉啪视频在线观看视频久| 制服丝袜另类专区制服| 国产 麻豆 日韩 欧美 久久| 欧美激情乱人伦| 成年黄页网站大全免费无码|