在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human TATA box-binding protein-like protein 1 (TBPL1)

  • 中文名稱:
    人TBPL1重組蛋白
  • 貨號:
    CSB-YP023240HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人TBPL1重組蛋白
  • 貨號:
    CSB-EP023240HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人TBPL1重組蛋白
  • 貨號:
    CSB-BP023240HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人TBPL1重組蛋白
  • 貨號:
    CSB-MP023240HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    TBPL1
  • Uniprot No.:
  • 別名:
    21 kDa TBP-like protein; 21kDa TBP like protein; Second TBP of unique DNA; Second TBP of unique DNA protein; STUD; TATA box binding protein like protein 1; TATA box binding protein-related factor 2; TATA box-binding protein-like protein 1; TATA box-binding protein-related factor 2; TBP like 1; TBP like protein; TBP related factor 2; TBP-like factor; TBP-like protein 1; TBP-related factor 2; TBP-related protein; tbpl1; TBPL1_HUMAN; TLF; TLP; TRF2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-186
  • 氨基酸序列
    MDADSDVALD ILITNVVCVF RTRCHLNLRK IALEGANVIY KRDVGKVLMK LRKPRITATI WSSGKIICTG ATSEEEAKFG ARRLARSLQK LGFQVIFTDF KVVNVLAVCN MPFEIRLPEF TKNNRPHASY EPELHPAVCY RIKSLRATLQ IFSTGSITVT GPNVKAVATA VEQIYPFVFE SRKEIL
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Part of a specialized transcription system that mediates the transcription of most ribosomal proteins through the 5'-TCT-3' motif which is a core promoter element at these genes. Seems to also mediate the transcription of NF1. Does not bind the TATA box.
  • 基因功能參考文獻:
    1. TLP Prevents p53 Degradation through Disrupting the p53-MDM2 Interaction. PMID: 28082682
    2. The interaction of TBP-like protein with TFIIA is essential to suppress proteasome-dependent turnover of TBP-like protein PMID: 27696626
    3. miR18a exhibits a protective role in colorectal cancer (CRC) via inhibiting proliferation, invasion and migration of CRC cells by directly targeting the TBPL1 gene. PMID: 26398009
    4. results suggest that activation of the p21 upstream promoter is mediated by interaction between specific regions of TLP and p53 PMID: 24594805
    5. Western blotting and immunohistochemistry both indicated a higher TBPL1 protein expression level in colorectal cancer tissue. siRNA for TBPL1 transfection obviously slowed down the cell proliferation in both SW-620 and HT-29 cells. PMID: 24870791
    6. TLP mediates p53-governed transcriptional activation of the p21 upstream promoter. PMID: 22511763
    7. Data show that during interphase, endogenous or exogenously expressed TRF2 is located almost exclusively in the nucleolus PMID: 15269281
    8. TLF is a functional regulator of transcription with targets distinct from those of TBP. PMID: 15767669

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    TBP family
  • 組織特異性:
    Ubiquitously expressed, with highest levels in the testis and ovary.
  • 數據庫鏈接:

    HGNC: 11589

    OMIM: 605521

    KEGG: hsa:9519

    STRING: 9606.ENSP00000237264

    UniGene: Hs.486507



主站蜘蛛池模板: 日本看片一二三区高清 | 强插女教师av在线| 日日噜噜夜夜狠狠视频| 少妇的肉体k8经典| 成年女人永久免费看片| 亚洲欧美国产制服图片区| 131美女爱做视频免费| 亚洲性啪啪无码av天堂| 久久久婷婷五月亚洲97号色| 国产亚洲综合区成人国产| 欧美亚洲国产手机在线有码 | 日本亚洲欧美综合在线| 欧美婷婷六月丁香综合色 | 无码福利在线观看1000集| 亚洲乱码中文字幕手机在线| 色婷婷综合缴情综免费观看| 亚洲综合无码久久精品综合| 麻豆文化传媒精品一区观看| 大香伊蕉在人线免费视频| 国产精品卡一卡2卡3卡4| 6699嫩草久久久精品影院| 美女裸体跪姿扒开屁股无内裤 | 国产又色又爽又刺激视频| 夫前人妻被灌醉侵犯在线| 亚洲成av人片高潮喷水| 色香欲综合成人免费视频| 男ji大巴进入女人的视频| 四虎国产精品永久在线国在线| 亚洲精品久久片久久久久| av无码午夜福利一区二区三区| 欧美三级在线播放线观看| 日本少妇毛茸茸高潮| 亚无码乱人伦一区二区| 四川骚妇无套内射舔了更爽| 无码日韩做暖暖大全免费不卡| 草的我好爽视频| 精品人妻码一区二区三区| 99在线精品一区二区三区| 成人网站精品久久久久| 人妻少妇精品一区二区三区| 东北少妇不带套对白|