在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human T-cell leukemia virus 2 Protein Tax-2 (tax)

  • 中文名稱:
    Recombinant Human T-cell leukemia virus 2 Protein Tax-2(tax)
  • 貨號:
    CSB-YP365933HQL
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human T-cell leukemia virus 2 Protein Tax-2(tax)
  • 貨號:
    CSB-EP365933HQL
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human T-cell leukemia virus 2 Protein Tax-2(tax)
  • 貨號:
    CSB-EP365933HQL-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human T-cell leukemia virus 2 Protein Tax-2(tax)
  • 貨號:
    CSB-BP365933HQL
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human T-cell leukemia virus 2 Protein Tax-2(tax)
  • 貨號:
    CSB-MP365933HQL
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    tax
  • Uniprot No.:
  • 別名:
    tax; Protein Tax-2; Trans-activating transcriptional regulatory protein of HTLV-2
  • 種屬:
    Human T-cell leukemia virus 2 (HTLV-2)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-331
  • 氨基酸序列
    MAHFPGFGQS LLYGYPVYVF GDCVQADWCP VSGGLCSTRL HRHALLATCP EHQLTWDPID GRVVSSPLQY LIPRLPSFPT QRTSRTLKVL TPPTTPVSPK VPPAFFQSMR KHTPYRNGCL EPTLGDQLPS LAFPEPGLRP QNIYTTWGKT VVCLYLYQLS PPMTWPLIPH VIFCHPRQLG AFLTKVPLKR LEELLYKMFL HTGTVIVLPE DDLPTTMFQP VRAPCIQTAW CTGLLPYHSI LTTPGLIWTF NDGSPMISGP YPKAGQPSLV VQSSLLIFEK FETKAFHPSY LLSHQLIQYS SFHNLHLLFD EYTNIPVSIL FNKEEADDNG D
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Transcriptional activator that activates both the viral long terminal repeat (LTR) and cellular promoters via activation of CREB, NF-kappa-B, SRF and AP-1 pathways. Binds to three 21 bp repeat elements located within the LTRs, referred to as Tax-responsive elements (TRE). Binding to TRE requires the interaction with CREB1 and CREBBP. Induces T-cell transformation, although much less efficiently than HTLV-1. Required for viral replication.
  • 基因功能參考文獻:
    1. A Luciferase Functional Quantitative Assay for Measuring NF-kB Promoter Transactivation Mediated by HTLV-1 and HTLV-2 Tax Proteins.( PMID: 28357663
    2. the role of Tax2-mediated activation of the nuclear factor kappa B (NF-kappaB) signalling pathway on the production of the anti-viral CC-chemokines MIP-1alpha, MIP-1beta and RANTES. PMID: 24116893
    3. In natural HTLV-1 infection cells expressing HTLV-1 Tax protein were significantly more frequent in clones of low abundance in vivo. PMID: 23555266
    4. The authors demonstrate that a nonubiquitinable, non-SUMOylable, and nonacetylable human T cell leukemia virus type 2 tax mutant retains a significant ability to activate transcription from a NF-kappaB-dependent promoter. PMID: 23135727
    5. HTLV-1 Tax1 and HTLV-2 Tax2 have many shared activities, but have a number of significantly distinct activities that appear to play key roles in HTLV-1 specific pathogenesis. We emphasize special attention to distinctions between Tax1 and Tax2. [REVIEW] PMID: 20017952
    6. These results show that HTLV-2 Tax2 by itself has a growth promoting activity toward a T-cell line CTLL-2 growth of Tax2-transformed CTLL-2 cells. These results show that HTLV-2 Tax2 by itself has a growth promoting activity toward a T-cell line CTLL-2. PMID: 17140451
    7. The authors demonstrate that Tax-2B is modified by ubiquitination and sumoylation. PMID: 19195675
    8. Virus-specific cytotoxic T cell responses against HTLV-2 Tax protein in HTLV-2 infection are characterized for the first time. PMID: 19657093

    顯示更多

    收起更多

  • 亞細胞定位:
    Host cytoplasm. Host nucleus. Note=Tax-2 is mainly found in the cytoplasm.
  • 蛋白家族:
    Deltaretrovirus Tax protein family
  • 數據庫鏈接:

    KEGG: vg:1491946



主站蜘蛛池模板: 亚洲另类春色校园小说| 国产亚洲精久久久久久无码77777 国产中年熟女高潮大集合 | 日韩精品真人荷官无码| 曰本极品少妇videossexhd| 人人做人人爽久久久精品| 久久热最新网站获取| 精品国产天堂综合一区在线| av午夜福利一片免费看久久| www国产亚洲精品| 伊人蕉久中文字幕无码专区| 国产成人亚洲精品无码蜜芽| 国产成+人+综合+亚洲 欧美| 亚洲va中文字幕无码一二三区| 国内自拍五区| 亚洲国产精品成人久久| 精品无人区卡一卡二卡三乱码| 国产色青青视频在线观看撒| 国产成人av在线一区二区三区| 狂野欧美激情性xxxx| 西西人体做爰大胆gogo| 国产a三级久久精品| 无码中文字幕人妻在线一区二区三区| 成在人线无码aⅴ免费视频| 色妞ww精品视频7777| 精品无码国产污污污免费网站 | 一边捏奶头一边啪高潮视频| 欧美成 人影片 aⅴ免费观看| 麻豆成人av不卡一二三区| 国产成人一区二区三区| 无码日韩人妻精品久久| 天堂а√中文最新版在线| 永久中文字幕免费视频网站| 亚洲精品一区二区三区中文字幕| 亚洲第一aaaaa片| 18禁黄网站禁片免费观看国产| 欧美性生交xxxxx无码久久久 | 亚洲性色成人av| 宝贝腿开大点我添添公视频免费| 日韩人妻无码一区二区三区| 久久人人爽人人爽人人爽| 午夜福利电影网站鲁片大全|