在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial (OXCT1)

In Stock
  • 中文名稱:
    人OXCT1重組蛋白
  • 貨號:
    CSB-EP017306HU
  • 規格:
    ¥1344
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    3 oxoacid CoA transferase 1; 3-oxoacid CoA-transferase 1; EC 2.8.3.5; OTTHUMP00000120012; OTTHUMP00000221550; OXCT; Oxct1; SCOT; Scot S; Scot-S; SCOT1_HUMAN; Somatic type succinyl CoA:3 oxoacid CoA transferase; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; Succinyl CoA:3 ketoacid CoA transferase; Succinyl CoA:3 ketoacid coenzyme A transferase 1 mitochondrial; Succinyl CoA:3 oxoacid CoA transferase; Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    56.1kDa
  • 表達區域:
    40-520aa
  • 氨基酸序列
    TKFYTDPVEAVKDIPDGATVLVGGFGLCGIPENLIDALLKTGVKGLTAVSNNAGVDNFGLGLLLRSKQIKRMVSSYVGENAEFERQYLSGELEVELTPQGTLAERIRAGGAGVPAFYTPTGYGTLVQEGGSPIKYNKDGSVAIASKPREVREFNGQHFILEEAITGDFALVKAWKADRAGNVIFRKSARNFNLPMCKAAETTVVEVEEIVDIGAFAPEDIHIPQIYVHRLIKGEKYEKRIERLSIRKEGDGEAKSAKPGDDVRERIIKRAALEFEDGMYANLGIGIPLLASNFISPNITVHLQSENGVLGLGPYPRQHEADADLINAGKETVTILPGASFFSSDESFAMIRGGHVDLTMLGAMQVSKYGDLANWMIPGKMVKGMGGAMDLVSSAKTKVVVTMEHSAKGNAHKIMEKCTLPLTGKQCVNRIITEKAVFDVDKKKGLTLIELWEGLTVDDVQKSTGCDFAVSPKLMPMQQIAN
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  • 基因功能參考文獻:
    1. Crystal structure of human SCOT, providing a molecular understanding of the reported mutations based on their potential structural effects. PMID: 23420214
    2. Case Report: Succinyl-CoA:3-ketoacid CoA transferase (SCOT) deficiency causes episodic ketoacidotic crises and no apparent symptoms between them. PMID: 20652411
    3. Data show that the ketone body metabolizing enzymes BDH1, BDH2, OXCT1 and ACAT1 were expressed at the mRNA and protein level in all glioma cell lines. PMID: 21791085
    4. Missense Mutations in succinyl-CoA:3-ketoacid CoA transferase is associated with Ketoacidosis. PMID: 21296660
    5. Results demonstrate that h-Scot-t is a single intronless gene specifically expressed in the testis. PMID: 11756565
    6. In SCOT-deficient patients retaining some residual activity, permanent ketosis may be absent. PMID: 15496607
    7. A 6-bp deletion at the splice donor site of intron 1 resulted in the absence of a full-length mature SCOT mRNA with faint amounts of aberrantly spliced transcripts using a cryptic splice donor site within exon 1. PMID: 16765626
    8. the R268H mutation is a ketoacidosis-causing one PMID: 17706444
    9. liver-specific silencing of the SCOT gene expression may be mediated in part by its 5'-flanking sequence PMID: 18648183
    10. The activities of pyruvate carboxylase (SCOT) were decreased by 65% in pancreatic islets of patients with type 2 diabetes. PMID: 19296078

    顯示更多

    收起更多

  • 相關疾病:
    Succinyl-CoA:3-oxoacid CoA transferase deficiency (SCOTD)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    3-oxoacid CoA-transferase family
  • 組織特異性:
    Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts.
  • 數據庫鏈接:

    HGNC: 8527

    OMIM: 245050

    KEGG: hsa:5019

    STRING: 9606.ENSP00000196371

    UniGene: Hs.278277



主站蜘蛛池模板: 成人黄网站高清免费视频| 精品久久久久久无码不卡| 国产亚洲一卡2卡3卡4卡网站 | 日日碰狠狠添天天爽无码| 欧美日韩在线第一页免费观看| 国产后进白嫩翘臀在线播放| 色综合亚洲一区二区小说| 成人伊人青草久久综合网| 一日本道a高清免费播放| k频道国产在线观看| 天堂在线www中文| 国产亚洲色欲色一色www| 中文字幕日韩精品有码视频| 久久综合久久鬼色| 国产成人精品永久免费视频| 欧美视频网站www色| 中文无码伦av中文字幕| 香蕉免费一区二区三区在| 亚洲精品拍拍央视网出文| 鲁鲁网亚洲站内射污| 99国产精品99久久久久久| 精品国产免费一区二区三区| 中文字幕久精品免费视频| 野外做受又硬又粗又大视频√| 国产一三四2021不卡| 亚洲欧美日本久久综合网站| av无码人妻中文字幕| 国产sm重味一区二区三区| 精品久久久久久无码中文字幕一区 | 成 人 色综合 综合网站| 国产在线观看免费人成视频| 少妇被爽到高潮喷水久久欧美精品| 艳妇臀荡乳欲伦交换在线播放| 亚洲伊人色综合www962| 欧美自拍另类欧美综合图片区| 少妇极品熟妇人妻无码| 国内揄拍国内精品对白| 国产精品系列无码专区| 色综合久久无码五十路人妻| 久久精品亚洲精品国产色婷| 亚洲精品综合欧美一区二区|