在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Splicing factor 3B subunit 3 (SF3B3) (T899I), partial

In Stock
  • 中文名稱:
    人SF3B3重組蛋白
  • 貨號:
    CSB-EP614890HU(M)
  • 規格:
    ¥1836
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    SF3B3
  • Uniprot No.:
  • 別名:
    Pre-mRNA-splicing factor SF3b 130 kDa subunit (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130)
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 來源:
    E.coli
  • 分子量:
    52.1 kDa
  • 表達區域:
    819-1217aa(T899I)
  • 氨基酸序列
    MAEEMVEAAGEDERELAAEMAAAFLNENLPESIFGAPKAGNGQWASVIRVMNPIQGNTLDLVQLEQNEAAFSVAVCRFSNIGEDWYVLVGVAKDLILNPRSVAGGFVYTYKLVNNGEKLEFLHKTPVEEVPAAIAPFQGRVLIGVGKLLRVYDLGKKKLLRKCENKHIANYISGIQTIGHRVIVSDVQESFIWVRYKRNENQLIIFADDTYPRWVTTASLLDYDTVAGADKFGNICVVRLPPNTNDEVDEDPTGNKALWDRGLLNGASQKAEVIMNYHVGETVLSLQKTTLIPGGSESLVYTTLSGGIGILVPFTSHEDHDFFQHVEMHLRSEHPPLCGRDHLSFRSYYFPVKNVIDGDLCEQFNSMEPNKQKNVSEELDRTPPEVSKKLEDIRTRYAF
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
  • 基因功能參考文獻:
    1. These results suggest SF3B3 as a key regulator of EZH2 pre-mRNA splicing and SF3B3 may represent a novel prognostic factor and potential therapeutic target in clear cell renal cell carcinoma PMID: 27879367
    2. our findings suggest a role for the elevated expression of SF3B3 in poor prognosis and tamoxifen resistance, leading to recurrence of estrogen receptor-positive breast cancer PMID: 25431237
    3. Report detection of SF3B3 gene mutations in oral cancer using high resolution melting analysis. PMID: 25651737
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    RSE1 family
  • 數據庫鏈接:

    HGNC: 10770

    OMIM: 605592

    KEGG: hsa:23450

    STRING: 9606.ENSP00000305790

    UniGene: Hs.514435



主站蜘蛛池模板: 无码人妻斩一区二区三区| 亚洲va在线va天堂xx xx| 天码欧美日本一道免费| 欧美真人性做爰一二区| 无码丰满熟妇| 视频在线+欧美十亚洲曰本| 又大又粗又爽免费视频a片| 国产国产精品人在线视| 国产成人综合久久亚洲精品| 国产欧美二区综合| 中文字幕av无码人妻| 精品人无码一区二区三区| 任我撸在线视频| 精品国产三级a在线观看| 久久国产欧美成人网站| 亚洲一区av无码专区在线观看| 亚洲精品久久久久国产| 无码av无码天堂资源网| 国产白浆喷水在线视频| 国产精品美女久久久m| 国产人成视频在线观看| 成人片黄网站色大片免费 | 3p人妻少妇对白精彩视频| 中字幕久久久人妻熟女天美传媒| 欲色欲色天天天www| 久久综合九色综合网站| 国产免费无码一区二区| 中文字幕精品视频在线看免费 | 免费精品国偷自产在线2020| 无码里番纯肉h在线网站| 亚在线观看免费视频入口| 国产无遮挡又黄又爽在线视频| 国产在线观看无码不卡| 后入到高潮免费观看| 真人做人试看60分钟免费| 永久免费毛片在线播放| 亚洲精品久久久久中文字幕二区| 成人av无码一区二区三区| 国产成人精品午夜福利在线观看 | 无码专区—va亚洲v专区vr| 久久国产乱子精品免费女|