在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Spermine synthase (SMS)

  • 中文名稱:
    人SMS重組蛋白
  • 貨號:
    CSB-YP021854HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SMS重組蛋白
  • 貨號:
    CSB-EP021854HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人SMS重組蛋白
  • 貨號:
    CSB-EP021854HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SMS重組蛋白
  • 貨號:
    CSB-BP021854HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SMS重組蛋白
  • 貨號:
    CSB-MP021854HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SMS
  • Uniprot No.:
  • 別名:
    MRSR; SMS; Snyder Robinson X linked mental retardation syndrome; Spermidine aminopropyltransferase; Spermine synthase; SPMSY; SpS; SPSY_HUMAN; SRS
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-366
  • 氨基酸序列
    AAARHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLATYTNKNGSFANL RIYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKELSQDSTGRVKRLPPIVRGGAID RYWPTADGRLVEYDIDEVVYDEDSPYQNIKILHSKQFGNILILSGDVNLAESDLAYTRAI MGSGKEDYTGKDVLILGGGDGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVL DNLKGDCYQVLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILDL SMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPSYLELWVFYTVW KKAKP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM).
  • 基因功能參考文獻:
    1. Missense mutations causing Snyder-Robinson Syndrome resulting in dysfunctional spermine synthase cause the destabilization of the protein. PMID: 26761001
    2. Results show that p.Y328C, a missense mutation in SMS is responsible for the patients having a mild form of Snyder-Robinson syndrome. PMID: 23696453
    3. Studied human spermine synthase activity by engineered mutations. PMID: 23468611
    4. This observation is used to demonstrate, computationally and experimentally, that a particular condition, Snyder-Robinson syndrome caused by the G56S spermine synthase mutation, might be ameliorated by small molecule binding. PMID: 23408511
    5. spermine synthase activity and the resulting elevation of the spermine:spermidine ratio does not alter susceptibility to tumor development initiated by c-Ha-Ras mutation or Apc loss PMID: 22258329
    6. the mutability of spermine synthase PMID: 21647366
    7. Mutations in the spermine synthase have been shown to be responsible for an X-linked intellectual disability condition known as Snyder-Robinson syndrome. PMID: 21318891
    8. each gene was associated with at least one main outcome: anxiety (SAT1, SMS), mood disorders (SAT1, SMOX), and suicide attempts (SAT1, OATL1). PMID: 21152090
    9. the genetic and epigenetic factors examined in this study show little influence on the expression level of SMS in suicide completers. PMID: 20059804
    10. Study reports the identification of a novel mutation at a highly conserved residue within the N-terminal region of spermine synthase (SMS) in a second family with Snyder-Robinson X-linked mental retardation syndrome. PMID: 18550699
    11. A missense mutation, p. V132G, in the X-linked SMS gene causes Snyder-Robinson syndrome. PMID: 19206178
    12. Data suggest that disruption of spermine synthase function may negatively affect regional brain volumes that subserve cognitive and motor abilities. PMID: 19277733

    顯示更多

    收起更多

  • 相關疾病:
    X-linked syndromic mental retardation Snyder-Robinson type (MRXSSR)
  • 蛋白家族:
    Spermidine/spermine synthase family
  • 數據庫鏈接:

    HGNC: 11123

    OMIM: 300105

    KEGG: hsa:6611

    STRING: 9606.ENSP00000385746

    UniGene: Hs.724874



主站蜘蛛池模板: 国产无遮挡色视频免费观看性色| 国产suv精品一区二区883| 国产亚洲日韩在线播放更多| 日韩成人无码v清免费| 激情射精爽到偷偷c视频无码| 亚洲精品中文字幕乱码| 亚洲精品久久久久久| 少妇与子乱在线观看| 亚洲中文字幕日产无码2020| 夜夜添无码一区二区三区| 日韩av无码一区二区三区| 国产模特嫩模私拍视频在线| 免费观看又色又爽又湿的视频| 久久偷看各类wc女厕嘘嘘偷窃| 亚洲精品~无码抽插| 激情久久亚洲小说| 久久国产人妻一区二区| 夜夜躁日日躁狠狠久久av| 日本黄页网站免费观看| 国产99视频精品免费视频76| 在线日韩av免费永久观看 | 亚洲精品av一二三区无码| 欧美激欧美啪啪片| 亚洲最新无码中文字幕久久| 国产午夜精品久久精品电影| 日本熟妇美熟bbw| 免费观看美女裸体网站| 四虎亚洲中文字幕无码永久 | 成人国产精品秘片多多| 性欧美暴力猛交69hd| 国产美女被遭高潮免费视频 | 欧美人成精品网站播放| 成人午夜福利视频镇东影视| 日韩欧美中文字幕在线三区| 秋霞国产精品一区二区| 一区二区三区无码高清视频| 国产精品免费无遮挡无码永久视频| 97久久婷婷五月综合色d啪蜜芽| 国产乱子伦一区二区三区=| 亚洲精品456在线播放 | 99久久婷婷国产一区二区|