在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Spermatogenesis-associated protein 2 (SPATA2)

Recombinant Human Spermatogenesis-associated protein 2 (SPATA2)

  • 中文名稱：
    人SPATA2重組蛋白
  • 貨號：
    CSB-YP891556HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SPATA2重組蛋白
  • 貨號：
    CSB-EP891556HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SPATA2重組蛋白
  • 貨號：
    CSB-EP891556HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SPATA2重組蛋白
  • 貨號：
    CSB-BP891556HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SPATA2重組蛋白
  • 貨號：
    CSB-MP891556HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    FLJ13167; KIAA0757; PD 1; PD1; PPP1R145; Protein phosphatase 1 regulatory subunit 145; SPAT2_HUMAN; SPATA 2; SPATA2; Spermatogenesis associated 2; Spermatogenesis associated PD1; Spermatogenesis associated protein 2; Spermatogenesis associated protein PD1; Spermatogenesis-associated protein 2; Spermatogenesis-associated protein PD1; Tamo
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-520
  • 氨基酸序列
    MGKPSSMDTK FKDDLFRKYV QFHESKVDTT TSRQRPGSDE CLRVAASTLL SLHKVDPFYR FRLIQFYEVV ESSLRSLSSS SLRALHGAFS MLETVGINLF LYPWKKEFRS IKTYTGPFVY YVKSTLLEED IRAILSCMGY TPELGTAYKL RELVETLQVK MVSFELFLAK VECEQMLEIH SQVKDKGYSE LDIVSERKSS AEDVRGCSDA LRRRAEGREH LTASMSRVAL QKSASERAAK DYYKPRVTKP SRSVDAYDSY WESRKPPLKA SLSLRKEPVA TDVGDDLKDE IIRPSPSLLT MASSPHGSPD VLPPASPSNG PALLRGTYFS TQDDVDLYTD SEPRATYRRQ DALRPDVWLL RNDAHSLYHK RSPPAKESAL SKCQSCGLSC SSSLCQRCDS LLTCPPASKP SAFPSKASTH DSLAHGASLR EKYPGQTQGL DRLPHLHSKS KPSTTPTSRC GFCNRPGATN TCTQCSKVSC DACLSAYHYD PCYKKSELHK FMPNNQLNYK STQLSHLVYR
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

相關(guān)產(chǎn)品

靶點詳情

  • 功能：
    Bridging factor that mediates the recruitment of CYLD to the LUBAC complex, thereby regulating TNF-alpha-induced necroptosis. Acts as a direct binding intermediate that bridges RNF31/HOIP, the catalytic subunit of the LUBAC complex, and the deubiquitinase (CYLD), thereby recruiting CYLD to the TNF-R1 signaling complex (TNF-RSC). Required to activate the 'Met-1'- (linear) and 'Lys-63'-linked deubiquitinase activities of CYLD. Controls the kinase activity of RIPK1 and TNF-alpha-induced necroptosis by promoting 'Met-1'-linked deubiquitination of RIPK1 by CYLD.
  • 基因功能參考文獻：
    1. SPATA2 has been described as a previously unrecognized factor in the linear ubiquitin chain assembly complex-dependent signaling pathways that serves as an adaptor between HOIP and CYLD, thereby enabling recruitment of CYLD to signaling complexes. PMID: 27545878
    2. The data reveal SPATA2 as a high-affinity binding partner of CYLD and HOIP, and a regulatory component of linear ubiquitin chain assembly complex-mediated NF-kappaB signaling. PMID: 27591049
    3. this study identifies SPATA2 as an important factor in the TNF signaling pathway with a substantial role for the effects mediated by the cytokine. PMID: 27458237
    4. The predicted PUB domain in the N-terminus of SPATA2 interacts with the USP domain of CYLD and SPATA2 is required for recruitment of CYLD to the TNF-alpha receptor-associated signaling complexes. PMID: 27307491
    5. The aim of this study was to investigate whether the HCP5, TNIP1, TNFAIP3, SPATA2 and COG6 genes were genetic risk factors for psoriasis in Chinese population. PMID: 25264125
    6. PD-L1 is highly expressed in tumours rather than tumour-free lymph nodes, which is closely correlated with the impairment of IFN-gamma production of tumour-infiltrating T-cells. PMID: 25093496
    7. Tumor-infiltrating NY-ESO-1-specific CD8+ T cells are negatively regulated by LAG-3 and PD-1 in human ovarian cancer. PMID: 20385810
    8. cloning and base sequence of the promoter region PMID: 12531478
    9. disappearance of TLD epitope reactivity from an otherwise stable EBV-specific response reflects selective loss of cognate antigen restimulation, not IL-7-dependent signals, and is immediately preceded by PD-1 upregulation to unprecedented levels. PMID: 19605492

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    SPATA2 family
  • 組織特異性：
    Present at high level in Sertoli cells, but not detected in spermatogenic cells (at protein level). Low expression in spleen, thymus and prostate.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 14681

    OMIM: 607662

    KEGG: hsa:9825

    STRING: 9606.ENSP00000289431

    UniGene: Hs.48513



主站蜘蛛池模板： 99久久精品免费看国产一区二区| 久久精品国产99精品国产2021| 成 人 色 网 站免费观看| 国产熟妇高潮呻吟喷水| 亚洲中文字幕无码一去台湾| 欧美精品无码久久久久久| 熟妇人妻一区二区三区四区| 少妇大叫太大太粗太爽了a片小说| 成人国产精品无码网站| 亚洲男男无套gv大学生| 国产精品揄拍100视频| 国产av综合影院| 精品偷拍被偷拍在线观看| 裸体丰满白嫩大尺度尤物| 四虎成人精品在永久免费| 成人aa免费视频在线播放| 欧美人与动人物牲交免费观看| 女人国产香蕉久久精品| 国产精品沙发午睡系列| 国产又黄又刺激又高潮的网站| 麻豆专媒体一区二区| 国产精品毛片一区二区三区| 精品一区二区三区免费播放| 人人妻人人澡人人爽人人精品97| 国产av国片精品有毛| 国产熟妇按摩3p高潮大叫| 色与欲影视天天看综合网| 337p日本欧洲亚洲大胆艺术图| а√天堂8资源在线官网| 无遮无挡爽爽免费毛片| 青青青草国产线观| 99久久精品6在线播放| 国产精品成熟老女人| 亚洲人av在线无码影院观看| 日本免费一本一二区三区| 亚洲 国产 韩国 欧美 在线| 激情欧美日韩一区二区| 尤物色综合欧美五月俺也去 | a片免费视频在线观看| 中文字幕人妻被公上司喝醉在线| 国产日韩av一区二区三区五区|