Recombinant Human Solute carrier organic anion transporter family member 3A1 (SLCO3A1), partial

中文名稱：

人SLCO3A1重組蛋白
貨號：

CSB-YP883432HU
規格：
來源：

Yeast
其他：

中文名稱：

人SLCO3A1重組蛋白
貨號：

CSB-EP883432HU
規格：
來源：

E.coli
其他：

中文名稱：

人SLCO3A1重組蛋白
貨號：

CSB-EP883432HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人SLCO3A1重組蛋白
貨號：

CSB-BP883432HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人SLCO3A1重組蛋白
貨號：

CSB-MP883432HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SLCO3A1
Uniprot No.：

Q9UIG8
別名：

SLCO3A1; OATP3A1; OATPD; SLC21A11; Solute carrier organic anion transporter family member 3A1; OATP3A1; Organic anion transporter polypeptide-related protein 3; OATP-RP3; OATPRP3; Organic anion-transporting polypeptide D; OATP-D; PGE1 transporter; Sodium-independent organic anion transporter D; Solute carrier family 21 member 11
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS.
基因功能參考文獻：
1. OATP3A1 functions as a bile acid efflux transporter that is up-regulated as an adaptive response to cholestasis. PMID: 30063921
2. SLCO3A1, a novel Crohn's disease-associated gene, mediates inflammatory processes in intestinal epithelial cells through NF-kappaB transcription activation. PMID: 24945726
3. Single nucleotide polymorhpisms of SLCO3A1 were associated with nicotine dependence. PMID: 22377092
4. OATP-D plays an important role in translocating prostaglandins in specialized tissues and cells. PMID: 14631946
5. Further evidence is provided for the involvement of OATPs in oligopeptide transport. OATP3A1 variants might be involved in the regulation of extracellular vasopressin concentration in human brain. PMID: 16971491
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亞細胞定位：

Cell membrane; Multi-pass membrane protein.
蛋白家族：

Organo anion transporter (TC 2.A.60) family
組織特異性：

Ubiquitous. Highly expressed in spleen and leukocytes. Generally the expression of isoform 1 is higher than that of isoform 2. Isoform 2 is particularly abundant in testis and brain. In testis, isoform 1 is detected in spermatogonia at different stages an
數據庫鏈接：

HGNC: 10952

OMIM: 612435

KEGG: hsa:28232

STRING: 9606.ENSP00000320634

UniGene: Hs.311187