在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Sodium- and chloride-dependent glycine transporter 2 (SLC6A5), partial

Recombinant Human Sodium- and chloride-dependent glycine transporter 2 (SLC6A5), partial

  • 中文名稱：
    人SLC6A5重組蛋白
  • 貨號：
    CSB-YP897479HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SLC6A5重組蛋白
  • 貨號：
    CSB-EP897479HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SLC6A5重組蛋白
  • 貨號：
    CSB-EP897479HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SLC6A5重組蛋白
  • 貨號：
    CSB-BP897479HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SLC6A5重組蛋白
  • 貨號：
    CSB-MP897479HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SLC6A5
  • Uniprot No.：
  • 別名：
    Glycine transporter; Glycine transporter type 2; GlyT-2; GlyT2; NET1; SC6A5_HUMAN; SC6AC5; Slc6a5; SLC6A5 solute carrier family 6 neurotransmitter transporter, glycine member 5; Slc6a9; Sodium and chloride dependent glycine transporter 2; Sodium- and chloride-dependent glycine transporter 2; Solute carrier family 6 member 5; Solute carrier family 6 neurotransmitter transporter glycine member 5
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses.
  • 基因功能參考文獻：
    1. analysis of the human SLC6A5 gene mutation associated with hyperekplexia PMID: 25480793
    2. Report that in the presence of a GlyT2 mechanism-based toxicity, reversible inhibitors might allow a tolerable balance between efficacy and toxicity. PMID: 23962079
    3. Constitutive endocytosis and turnover of the neuronal glycine transporter GlyT2 is dependent on ubiquitination of a C-terminal lysine cluster. PMID: 23484054
    4. A novel dominant hyperekplexia mutation Y705C alters trafficking and biochemical properties of the presynaptic glycine transporter GlyT2. PMID: 22753417
    5. This study firmly establishes the combination of missense, nonsense, frameshift, and splice site mutations in the GlyT2 gene as the second major cause of startle disease. PMID: 22700964
    6. A transgenic cell line is studied in which green fluorescent protein (GFP) is expressed under the control of the promoter for the glycine transporter GlyT2 during zebrafish development. PMID: 21397641
    7. Inspiratory-modulated neurons with pacemaker properties are present in the preBotzinger complex of newborn transgenic mice and express the glycine tranporter (GlyT)2 protein. PMID: 20219997
    8. Variants not associated with bipolar disorder or schizophrenia. PMID: 16691125
    9. SLC6A5 mutations result in defective subcellular GlyT2 localization, decreased glycine uptake or both, with selected mutations affecting predicted glycine and Na+ binding sites. PMID: 16751771
    10. results are consistent with GLYT2 being a disease gene in human hyperekplexia PMID: 16884688
    11. SLC6A5 gene is associated with schizophrenia. PMID: 18638388

    顯示更多

    收起更多

  • 相關疾病：
    Hyperekplexia 3 (HKPX3)
  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A5 subfamily
  • 組織特異性：
    Expressed in medulla, and to a lesser extent in spinal cord and cerebellum.
  • 數據庫鏈接：

    HGNC: 11051

    OMIM: 604159

    KEGG: hsa:9152

    STRING: 9606.ENSP00000434364

    UniGene: Hs.136557



主站蜘蛛池模板： 亚洲乱码国产乱码精品精大量 | 蜜桃av色偷偷av老熟女| 又色又污又爽又黄的网站| 亚洲狠狠色丁香婷婷综合| 熟女人妻aⅴ一区二区三区麻豆| 亚洲高清成人av电影网站| 丰满人妻无奈张开双腿av| 国产人妻精品一区二区三首| 熟女肥臀白浆大屁股一区二区| 毛多水多www偷窥小便| 国产精品久久久久9999赢消| 无人区码一码二码w358cc| 天干天干夜啦天干天干国产| 精品成人毛片一区二区| 免费无码肉片在线观看| 人妻丰满熟妇av无码区乱| 7m精品福利视频导航| 国产亚洲福利在线视频| 成人午夜福利免费体验区| 国产丝袜美女| 国产sm调教视频在线观看 | 各种少妇正面bbw撒尿| r级无码视频在线观看| 国产在线观看无码的免费网站| 亚洲国产精品嫩草影院永久| 国产放荡对白视频在线观看| av小次郎收藏| 久久这里只有精品18| 国产性猛交╳xxx乱大交| 中文字幕中文有码在线| 99热这里只有是精品2| 国产在线精品一区二区中文| 亚洲熟妇色自偷自拍另类| 国产精品自在线拍国产| 天堂岛国av无码免费无禁网站| 色99久久久久高潮综合影院| 无码h肉动漫在线观看| 亚洲不卡av不卡一区二区| 99久e在线精品视频在线| 国产成人精品无码免费看| 日韩视频在线观看|