在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Sn1-specific diacylglycerol lipase alpha (DAGLA), partial

Recombinant Human Sn1-specific diacylglycerol lipase alpha (DAGLA), partial

  • 中文名稱：
    Recombinant Human Sn1-specific diacylglycerol lipase alpha(DAGLA) ,partial
  • 貨號：
    CSB-YP897490HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Sn1-specific diacylglycerol lipase alpha(DAGLA) ,partial
  • 貨號：
    CSB-EP897490HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Human Sn1-specific diacylglycerol lipase alpha(DAGLA) ,partial
  • 貨號：
    CSB-EP897490HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Sn1-specific diacylglycerol lipase alpha(DAGLA) ,partial
  • 貨號：
    CSB-BP897490HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Sn1-specific diacylglycerol lipase alpha(DAGLA) ,partial
  • 貨號：
    CSB-MP897490HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    DAGLA
  • Uniprot No.：
  • 別名：
    C11orf11; Chromosome 11 open reading frame 11 ; DAGL(ALPHA); Dagla; DAGLALPHA; DGL alpha; DGL-alpha; DGLA_HUMAN; Diacylglycerol lipase alpha; KIAA0659; Neural stem cell derived dendrite regulator; Neural stem cell-derived dendrite regulator; NSDDR; Sn1-specific diacylglycerol lipase alpha
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Serine hydrolase that hydrolyzes arachidonic acid-esterified diacylglycerols (DAGs) to produce the principal endocannabinoid, 2-arachidonoylglycerol (2-AG). Preferentially hydrolyzes sn-1 fatty acids from diacylglycerols (DAG) that contain arachidonic acid (AA) esterified at the sn-2 position to biosynthesize 2-AG. Has negligible activity against other lipids including monoacylglycerols and phospholipids. Plays a key role in regulating 2-AG signaling in the central nervous system (CNS). Regulates 2-AG involved in retrograde suppression at central synapses. Supports axonal growth during development and adult neurogenesis. Plays a role for eCB signaling in the physiological regulation of anxiety and depressive behaviors. Regulates also neuroinflammatory responses in the brain, in particular, LPS-induced microglial activation.
  • 基因功能參考文獻：
    1. phenotypes associated with rare CNR1 variants are reminiscent of those implicated in the theory of clinical endocannabinoid deficiency syndrome. The severe phenotypes associated with rare DAGLA variants underscore the critical role of rapid 2-AG synthesis and the endocannabinoid system in regulating neurological function and development PMID: 29145497
    2. In subcutaneous adipose tissue, DAGL-a mRNA was upregulated and fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) mRNAs were down-regulated in obese subjects, but the diets had no influence. PMID: 24616451
    3. PLC-beta1 and DAGL-alpha are detected in discrete brain regions, with a marked predominance of pyramidal morphologies of positive cortical cells.[review] PMID: 24076015
    4. DAGLalpha mRNA expression is lowest in early life and adulthood, peaking between school age and young adulthood. PMID: 22827915
    5. This gene was functionally characterized as a diacylglycerol-lipase (DAGL), specifically referred to as DAGL alpha. This enzyme may play a role in the biosynthesis of the endocannbinoid 2-arachidonoylglycerol (2-AG). PMID: 14610053

    顯示更多

    收起更多

  • 相關疾病：
    Spinocerebellar ataxia 20 (SCA20)
  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Cell projection, dendritic spine membrane; Multi-pass membrane protein.
  • 蛋白家族：
    AB hydrolase superfamily, Lipase family
  • 組織特異性：
    Highly expressed in brain and pancreas.
  • 數據庫鏈接：

    HGNC: 1165

    OMIM: 608687

    KEGG: hsa:747

    STRING: 9606.ENSP00000257215

    UniGene: Hs.241564



主站蜘蛛池模板： 精品少妇人妻av免费久久久| 欧洲av无码放荡人妇网站| 熟女人妻aⅴ一区二区三区60路| 成人av片无码免费网站| 国产丝袜在线精品丝袜不卡| 天天躁夜夜躁狠狠躁2020| 亚洲精品国男人在线视频| 狠狠人妻久久久久久综合蜜桃| 欧洲熟妇色xxxx欧美老妇| 国产日韩另类综合11页| 国产丰满人妻一区二区| 精品久久香蕉国产线看观看亚洲| 娇小萝被两个黑人用半米长| 老司机在线精品视频网站| 亚洲综合中文字幕无线码| 日日噜噜夜夜爽爽| 国产日产欧产精品| 国产欧美一区二区精品仙草咪| 欧美人与性动交g欧美精器| 少妇三级全黄| 在线毛片片免费观看| 2021自拍偷在线精品自拍偷| 无码日韩精品一区二区人妻 | 99re6热视频这里只精品首页| 国产360激情盗摄全集| 国产乱理伦片在线观看| 无码免费无线观看在线视频| 亚洲综合最新无码2020av| 国产免费高清69式视频在线观看 | 香港三级日本三级妇三级| 久久99亚洲含羞草影院| 亚洲国产香蕉碰碰人人| 私人毛片免费高清影视院| 久久久久国产精品人妻aⅴ天堂| 在线观看国产丝袜控网站| 中国无码人妻丰满熟妇啪啪软件| 久久精品亚洲一区二区三区浴池| 好爽太紧了舒服视频| 狠狠色婷婷久久综合频道毛片| 色翁荡息又大又硬又粗又爽| 久热这里只有精品99在线观看 |