在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Small muscular protein (SMPX)

  • 中文名稱:
    人SMPX重組蛋白
  • 貨號:
    CSB-YP887043HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人SMPX重組蛋白
  • 貨號:
    CSB-EP887043HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人SMPX重組蛋白
  • 貨號:
    CSB-BP887043HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人SMPX重組蛋白
  • 貨號:
    CSB-MP887043HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    SMPX
  • Uniprot No.:
  • 別名:
    1010001C09Rik; Csl; DFNX4; RP23-60A1.5; Small muscular protein; SMPX; SMPX_HUMAN; Stretch-responsive skeletal muscle protein
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-88
  • 氨基酸序列
    MNMSKQPVSN VRAIQANINI PMGAFRPGAG QPPRRKECTP EVEEGVPPTS DEEKKPIPGA KKLPGPAVNL SEIQNIKSEL KYVPKAEQ
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.
  • 基因功能參考文獻:
    1. detected a single nucleotide variation in two male controls with normal hearing, SMPX c.55A>G (p.Asn19Asp), which has been annotated as a rare variant in the Single Nucleotide Polymorphism (dbSNP) (rs759552778) and Exome Aggregation Consortium (ExAC) databases. This study has enriched the mutation spectrum of the SMPX gene PMID: 29559740
    2. Results show that SMPX expression is regulated by NOR-1 which binds to SMPX promoter and induces its activity promoting myotube differentiation. PMID: 27181368
    3. We report the first SMPX (DFNX4) mutation in a North American family. Our findings contribute to the existing genotypic and phenotypic spectrum of SMPX associated hearing loss. Furthermore, our data suggest that exome sequencing is promising in the genetic diagnosis of hearing loss PMID: 29287879
    4. A novel frameshift mutation in SMPX. PMID: 28542515
    5. Audiological, medical, and family histories were collected and family members interviewed to compare hearing thresholds and case histories between cases with mutations in SMPX versus POU3F4. PMID: 24687041
    6. SMPX is localized predominantly in repetitive double stripes flanking the Z-disc, and not present in nuclei. PMID: 24936977
    7. Data indicate founder mutation in exon 3 (c.99delC) of SMPX that cosegregates in two Newfoundland families. PMID: 22911656
    8. Demonstrate phenotypic heterogeneity in large family with an X-linked pattern of inherited sensorineural hearing impairment with SMPX mutations. PMID: 21893181
    9. Our study identified mutations in SMPX in patients with X-chromosomal hearing impairment and suggested that the stress response of mechanically challenged inner-ear cells might critically depend on SMPX function. PMID: 21549336
    10. This study identifies SMPX as a gene in which variation is associated with X-linked deafness and illustrates that NGS is instrumental in the efficient identification of disease-causing variants in unexpected genes. PMID: 21549342

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Deafness, X-linked, 4 (DFNX4)
  • 蛋白家族:
    SMPX family
  • 組織特異性:
    Preferentially and abundantly expressed in heart and skeletal muscle.
  • 數據庫鏈接:

    HGNC: 11122

    OMIM: 300066

    KEGG: hsa:23676

    STRING: 9606.ENSP00000368808

    UniGene: Hs.734084



主站蜘蛛池模板: 日韩av无码社区一区二区三区| 日韩超碰人人爽人人做人人添| 中文字幕人成乱码熟女香港| 永久久久免费人妻精品| 亚洲精品无码久久久久不卡| 国产午夜亚洲精品午夜鲁丝片| 精品一区二区三区无码视频| 在线观看国产精品电影| 人人爽人人爽人人片av免费| 久久一卡二卡三卡四卡| 无码熟妇αⅴ人妻又粗又大 | 玩弄人妻少妇500系列视频| 日韩成人无码v清免费 | 国产精品av在线| 看曰本女人大战黑人视频| 亚洲精品无人区| 精品免费国产一区二区| 亚洲区激情区无码区日韩区| 亚洲日韩欧洲乱码av夜夜摸| 快好爽射给我视频| 国产成人92精品午夜福利| 天天天狠天天碰天天爱| 青青草大香焦在线综合视频| 女邻居的大乳中文字幕| 狠狠色老熟妇老熟女| 性欧美丰满熟妇xxxx性| 极品熟妇大蝴蝶20p| 亚洲 欧美 另类图片| 亚洲 欧美精品suv| 亚瑟国产精品久久| 日本新janpanese乱熟| 久久綾合久久鬼色88| 2020国产在线拍揄自揄视频| 亚洲欧美国产精品久久久久久久| 欧美乱大交av片久久123| 国产精品区一区二区三在线播放| 人妻av中文系列| 人妻精品久久久久中文字幕 | 国产成人亚洲精品无码电影| 玩弄丰满少妇人妻视频| 肉色超薄丝袜脚交一区二区 |