在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Sialic acid-binding Ig-like lectin 14 (SIGLEC14), partial

Recombinant Human Sialic acid-binding Ig-like lectin 14 (SIGLEC14), partial

  • 中文名稱：
    人SIGLEC14重組蛋白
  • 貨號：
    CSB-YP600195HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SIGLEC14重組蛋白
  • 貨號：
    CSB-EP600195HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SIGLEC14重組蛋白
  • 貨號：
    CSB-EP600195HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SIGLEC14重組蛋白
  • 貨號：
    CSB-BP600195HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SIGLEC14重組蛋白
  • 貨號：
    CSB-MP600195HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SIGLEC14
  • Uniprot No.：
  • 別名：
    Sialic acid binding Ig like lectin 14; Sialic acid-binding Ig-like lectin 14; SIG14_HUMAN; Siglec 14 ; Siglec-14; SIGLEC14
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors.
  • 基因功能參考文獻：
    1. Demonstrate an association between SIGLEC14 expression and clinical tuberculosis, mycobacterium tuberculosis replication, and BCG-specific T-cell cytokine production. PMID: 28454648
    2. SIGLEC14 expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    3. An unbiased screen revealed Hsp70 as a ligand for Siglec-5 and Siglec-14. Hsp70 stimulation through Siglec-5 delivers an anti-inflammatory signal, while stimulation through Siglec-14 is pro-inflammatory. PMID: 26459514
    4. Genome-wide association analyses revealed common DNA variants in PLG, LPA, and near SIGLEC14 that contribute to plasma plasminogen level variation. PMID: 25208887
    5. Data indicate that the Siglec-5/14 genotype influences neutrophil responses to group B Streptococcus. PMID: 24799499
    6. Siglec-14 and its downstream signaling pathway facilitate the "infection-inflammation-exacerbation" axis of COPD disease progression PMID: 23519826
    7. Siglec-14 and Siglec-5 appear to be the first glycan binding paired receptors. Near-complete sequence identity of the amino-terminal part of human Siglec-14 and Siglec-5 indicates partial gene conversion between SIGLEC14 and SIGLEC5. PMID: 17012248
    8. The presence of the "SIGLEC14 null" allele in all human populations we tested implies an ancient origin, while its allelic frequency is higher in Asians compared with Africans and Europeans. Siglec-14 may play some role in bacterial infection. PMID: 19369701

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family
  • 組織特異性：
    Mainly expressed in hematopoietic tissues including bone marrow, spleen and fetal liver. Also detected in lung and testis.
  • 數據庫鏈接：

    HGNC: 32926

    KEGG: hsa:100049587

    STRING: 9606.ENSP00000354090

    UniGene: Hs.707374



主站蜘蛛池模板： 99久久国产露脸精品竹菊传媒| 国产毛片精品av一区二区| 狠狠色综合久久丁香婷婷| 中国国产1级毛卡片| 人妻无码久久一区二区三区免费 | 中文无码第3页不卡av| 丰满岳妇乱一区二区三区| 十八18禁国产精品www| 国产成人无码a区视频| 999成人精品视频在线| 亚洲国产a∨无码中文777| 亚洲日本va中文字幕| 国产自愉自愉免费精品七区| 成人无码专区免费播放三区| 久久精品久久久久观看99水蜜桃 | 国产99在线 | 亚洲| 国产巨大爆乳在线观看| 亚洲精品无码久久久久不卡| 精品国精品国产自在久国产应用| 久久99国产精品成人| 久久国产偷任你爽任你| 国产又a又黄又潮娇喘视频| 国产精品兄妹在线观看麻豆| 无码专区—va亚洲v天堂麻豆| 午夜性刺激在线视频免费| 国模冰莲自慰肥美胞极品人体图 | 国产成人午夜福利在线播放| 国产精品55夜色66夜色| 99久热re在线精品99 6热视频| 国产成人无码免费视频在线| 国产成人亚洲无吗淙合青草| 国内揄拍国内精品少妇| 成年无码av片在线| 久久久国产99久久国产久麻豆| 国产一国产aa毛片| 午夜精品国产精品大乳美女| 国产精品黄页免费高清在线观看| 国产成人av在线一区二区三区| 夜夜嗨av一区二区三区| 青草伊人久久综在合线亚洲观看 | 果冻传媒18禁免费视频 |