在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (ACADSB)

  • 中文名稱:
    Recombinant Human Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial(ACADSB)
  • 貨號:
    CSB-YP001128HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Human Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial(ACADSB)
  • 貨號:
    CSB-EP001128HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Human Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial(ACADSB)
  • 貨號:
    CSB-EP001128HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Human Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial(ACADSB)
  • 貨號:
    CSB-BP001128HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Human Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial(ACADSB)
  • 貨號:
    CSB-MP001128HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    ACADSB
  • Uniprot No.:
  • 別名:
    2 MEBCAD; 2 methyl branched chain acyl CoA dehydrogenase; 2 methylbutyryl CoA dehydrogenase; 2 methylbutyryl coenzyme A dehydrogenase; 2-MEBCAD; 2-methyl branched chain acyl-CoA dehydrogenase; 2-methylbutyryl-CoA dehydrogenase; 2-methylbutyryl-coenzyme A dehydrogenase; ACAD7; ACADSB; ACDSB_HUMAN; acyl CoA dehydrogenase; short/branched chain; acyl Coenzyme A dehydrogenase short branched chain; mitochondrial; OTTHUMP00000020685; OTTHUMP00000046795; SBCAD; Short/branched chain specific acyl-CoA dehydrogenase; short/branched chain specific acyl-CoA dehydrogenase; mitochondrial
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    34-432
  • 氨基酸序列
    KSSQSEA LLNITNNGIH FAPLQTFTDE EMMIKSSVKK FAQEQIAPLV STMDENSKME KSVIQGLFQQ GLMGIEVDPE YGGTGASFLS TVLVIEELAK VDASVAVFCE IQNTLINTLI RKHGTEEQKA TYLPQLTTEK VGSFCLSEAG AGSDSFALKT RADKEGDYYV LNGSKMWISS AEHAGLFLVM ANVDPTIGYK GITSFLVDRD TPGLHIGKPE NKLGLRASST CPLTFENVKV PEANILGQIG HGYKYAIGSL NEGRIGIAAQ MLGLAQGCFD YTIPYIKERI QFGKRLFDFQ GLQHQVAHVA TQLEAARLLT YNAARLLEAG KPFIKEASMA KYYASEIAGQ TTSKCIEWMG GVGYTKDYPV EKYFRDAKIG TIYEGASNIQ LNTIAKHIDA EY
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Short and branched chain specific acyl-CoA dehydrogenase that catalyzes the removal of one hydrogen from C-2 and C-3 of the fatty acyl-CoA thioester, resulting in the formation of trans-2-enoyl-CoA. Among the different mitochondrial acyl-CoA dehydrogenases, acts specifically on short and branched chain acyl-CoA derivatives such as (S)-2-methylbutyryl-CoA as well as short straight chain acyl-CoAs such as butyryl-CoA. Plays an important role in the metabolism of L-isoleucine by catalyzing the dehydrogenation of 2-methylbutyryl-CoA, one of the steps of the L-isoleucine catabolic pathway. Can also act on valproyl-CoA, a metabolite of valproic acid, an antiepileptic drug.
  • 基因功能參考文獻:
    1. the c.1165 A>G mutation before knowing whether the optimal screening cut-off would minimize true positives or false negatives for SBCADD associated with this mutation. PMID: 23712021
    2. Strong candidate gene for mitochondrial disease, based on recessive mutations detected in infantile patients PMID: 22277967
    3. These findings confirm that SBCAD deficiency can be identified through newborn screening by acylcarnitine analysis. PMID: 20547083
    4. Differences between the rat and human enzyme at positions 383, 222, and 220 alter substrate specificity without affecting substrate binding. PMID: 12855692
    5. Identification and characterization of an IVS3+3A>G mutation (c.303+3A>G) in the SBCAD gene, and provide evidence that this mutation is disease-causing. PMID: 16317551
    6. Results examine the mechanistic basis for dysfunction of the common variant short-chain acyl-CoA dehydrogenases and demonstrate that mutations can have a large impact on the redox properties of the enzyme. PMID: 16331963
    7. Results indicate that substrate redox activation occurs in short-chain acyl-CoA dehydrogenase leading to a large enzyme midpoint potential shift. PMID: 16331964

    顯示更多

    收起更多

  • 相關疾病:
    Short/branched-chain acyl-CoA dehydrogenase deficiency (SBCADD)
  • 亞細胞定位:
    Mitochondrion matrix.
  • 蛋白家族:
    Acyl-CoA dehydrogenase family
  • 組織特異性:
    Ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 91

    OMIM: 600301

    KEGG: hsa:36

    STRING: 9606.ENSP00000357873

    UniGene: Hs.81934



主站蜘蛛池模板: 好男人www社区| 国产乱妇无码大片在线观看| 都市激综合小说区另类区| 国产美女自慰在线观看| 久久久久88色偷偷| 亚洲 欧美 天堂 综合| 国产色诱视频在线播放网站| 麻豆成人精品国产免费| 国内精品自在自线| 久久精品国产一区二区三区| 成人av久久一区二区三区| 中文字幕大看蕉在线观看| 精品国产品香蕉在线| 人人妻人人澡人人爽人人dvd| 日韩伦人妻无码| 精品国产一区二区三区国产区| 久久99精品久久久久久不卡| 国产精品亚洲αv天堂无码| 亚洲中文字幕无码av永久| 久久无码人妻国产一区二区| 亚洲a∨无码国产精品久久网| 亚洲第一成人网站| 色哟哟网站在线观看| 欧亚乱熟女一区二区三区在线| 中日韩va无码中文字幕| 999久久久免费精品国产| 国产精品人妻一区二区三区四| h无码动漫在线观看| 日韩内射美女片在线观看网站| 人人妻人人澡av天堂香蕉| 亚洲成av人在线视| 国内大量揄拍人妻在线视频| 无遮挡男女激烈动态图| 性暴力欧美猛交在线播放| 天天爽夜夜爽人人爽一区二区| 国产成人精品.视频| 青青草国产免费国产是公开| 三上悠亚久久精品| 成人视频在线观看| 无码av不卡免费播放| 国产乱理伦片在线观看|