在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B)

Recombinant Human Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PPP2R1B)

  • 中文名稱：
    人PPP2R1B重組蛋白
  • 貨號：
    CSB-YP018563HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PPP2R1B重組蛋白
  • 貨號：
    CSB-EP018563HU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PPP2R1B重組蛋白
  • 貨號：
    CSB-EP018563HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PPP2R1B重組蛋白
  • 貨號：
    CSB-BP018563HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PPP2R1B重組蛋白
  • 貨號：
    CSB-MP018563HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    2AAB_HUMAN; beta isoform of regulatory subunit A; protein phosphatase 2; PP2A A beta; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta; PP2A; subunit A; PR65 beta isoform; PP2A; subunit A; R1 beta isoform; PPP2R1B; PPP4R1; PR65B; protein phosphatase 2 (formerly 2A); regulatory subunit A (PR 65); beta isoform; protein phosphatase 2 (formerly 2A); regulatory subunit A; beta isoform; Protein phosphatase 2; regulatory subunit A; beta; Protein phosphatase 2; structural/regulatory subunit A; beta; protein phosphatase 2; structural/regulatory subunit A; beta isoform; serine/threonine protein phosphatase 2A 65 kDa regulatory subunit A; beta isoform; serine/threonine protein phosphatase 2A; 65 kDa regulatory subunit A; beta isoform; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    2-601
  • 氨基酸序列
    AGASELGTG PGAAGGDGDD SLYPIAVLID ELRNEDVQLR LNSIKKLSTI ALALGVERTR SELLPFLTDT IYDEDEVLLA LAEQLGNFTG LVGGPDFAHC LLPPLENLAT VEETVVRDKA VESLRQISQE HTPVALEAYF VPLVKRLASG DWFTSRTSAC GLFSVCYPRA SNAVKAEIRQ QFRSLCSDDT PMVRRAAASK LGEFAKVLEL DSVKSEIVPL FTSLASDEQD SVRLLAVEAC VSIAQLLSQD DLETLVMPTL RQAAEDKSWR VRYMVADRFS ELQKAMGPKI TLNDLIPAFQ NLLKDCEAEV RAAAAHKVKE LGENLPIEDR ETIIMNQILP YIKELVSDTN QHVKSALASV IMGLSTILGK ENTIEHLLPL FLAQLKDECP DVRLNIISNL DCVNEVIGIR QLSQSLLPAI VELAEDAKWR VRLAIIEYMP LLAGQLGVEF FDEKLNSLCM AWLVDHVYAI REAATNNLMK LVQKFGTEWA QNTIVPKVLV MANDPNYLHR MTTLFCINAL SEACGQEITT KQMLPIVLKM AGDQVANVRF NVAKSLQKIG PILDTNALQG EVKPVLQKLG QDEDMDVKYF AQEAISVLAL A
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.
  • 基因功能參考文獻(xiàn)：
    1. MicroRNA-587 antagonizes 5-fluorouracil-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer. PMID: 26247730
    2. For PPP2R1B, no mutations were detected in our samples. PMID: 23588898
    3. Data show that the only gene that was expressed, although not at high levels, in all the cells carrying the 11q23.1 amplification was PPP2R1B. PMID: 21420167
    4. Data show that PR65-dominated fluctuations of PP2A have the effect of opening and closing the enzyme's substrate binding/catalysis interface, as well as altering the positions of certain catalytic residues. PMID: 20133745
    5. apoptosis mediated by Fas, TNF-alpha, and TRAIL in U937 cells is suppressed by calyculin A, an inhibitor of type-1 and type-2A protein phosphatases PMID: 14576831
    6. PPP2R1B has a role in regulating activity of specific downstream target proteins for cell cycle regulation in colorectal cancers PMID: 14767517
    7. Functional interaction between PR65, a regulatory subunit of the protein phosphatase 2A (PP2A), and CFTR was shown. PMID: 15936019
    8. These data suggest the possibility that aberrant transcripts of PPP2R1B might be associated with the development of HCC. PMID: 17324501
    9. PPP2R1B genes may not play a role in the carcinogenesis of cervical cancer. Mutations of PPP2R1B gene are not frequent in cervical cancer. PMID: 17343570
    10. PPP2R1B, together with NPAT and CUL5, is implicated in the deregulation of the cell-cycle and apoptosis regulators and in the pathogenesis of B-CLL. PMID: 17449237
    11. These observations identify PP2A Abeta as a tumor suppressor gene that transforms immortalized human cells by regulating the function of RalA. PMID: 17540176

    顯示更多

    收起更多

  • 蛋白家族：
    Phosphatase 2A regulatory subunit A family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9303

    OMIM: 603113

    KEGG: hsa:5519

    STRING: 9606.ENSP00000311344

    UniGene: Hs.269128



主站蜘蛛池模板： 国产精品久免费的黄牛仔短裤| 五十老熟妇乱子伦免费观看| 国产午夜理论片不卡| 国产成人精品三级在线影院| 精品国产午夜理论片不卡精品| 天天躁日日躁狠狠躁免费麻豆| 国产精品一区二区在线观看| 欧美嫩交一区二区三区| 精品国产日韩亚洲一区| 午夜精品久久久久久| 刺激性视频黄页| 亚洲精品无码你懂的| 亚洲视频日韩视欧美视频| 无码人妻av一区二区三区蜜臀| 97久久久久人妻精品区一| 人人婷婷人人澡人人爽| 久久久一本精品99久久精品88 | 成人影片一区免费观看| 久久香蕉国产线看观看怡红院妓院| 一本一本久久a久久综合精品| 国产青榴视频在线观看| 亚洲国产婷婷六月丁香| 狠狠精品久久久无码中文字幕| 国产精品第一区揄拍无码| 亚洲精品一区二区三区四区乱码| 亚洲日韩激情无码一区| 亚洲中文字幕不卡无码| 人与嘼av免费| 国产激情久久久久影院老熟女| 狠狠躁夜夜躁人人爽天天古典| 巨爆乳中文字幕巨爆区巨爆乳无码 | 66lu国产在线观看| 国产精品无码一区二区桃花视频| 男人的天堂av社区在线| 久久人人97超碰国产公开| 精品少妇人妻av免费久久久| 粉嫩被粗大进进出出视频| 伊人中文字幕无码专区| 99re久久精品国产| 综合在线 亚洲 成人 欧美| 亚洲精品综合一区二区|