在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (PPP2R2D)

  • 中文名稱:
    人PPP2R2D重組蛋白
  • 貨號:
    CSB-YP727750HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PPP2R2D重組蛋白
  • 貨號:
    CSB-EP727750HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PPP2R2D重組蛋白
  • 貨號:
    CSB-EP727750HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PPP2R2D重組蛋白
  • 貨號:
    CSB-BP727750HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PPP2R2D重組蛋白
  • 貨號:
    CSB-MP727750HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    2ABD_HUMAN; MDS026; PP2A subunit B isoform B55-delta; PP2A subunit B isoform delta; PP2A subunit B isoform PR55-delta; PP2A subunit B isoform R2-delta; PPP2R2D; Protein phosphatase 2 regulatory subunit B delta; Protein phosphatase 2 regulatory subunit B delta isoform; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-453
  • 氨基酸序列
    MAGAGGGGCP AGGNDFQWCF SQVKGAIDED VAEADIISTV EFNYSGDLLA TGDKGGRVVI FQREQENKSR PHSRGEYNVY STFQSHEPEF DYLKSLEIEE KINKIRWLPQ QNAAHFLLST NDKTIKLWKI SERDKRAEGY NLKDEDGRLR DPFRITALRV PILKPMDLMV EASPRRIFAN AHTYHINSIS VNSDHETYLS ADDLRINLWH LEITDRSFNI VDIKPANMEE LTEVITAAEF HPHQCNVFVY SSSKGTIRLC DMRSSALCDR HSKFFEEPED PSSRSFFSEI ISSISDVKFS HSGRYMMTRD YLSVKVWDLN MESRPVETHQ VHEYLRSKLC SLYENDCIFD KFECCWNGSD SAIMTGSYNN FFRMFDRDTR RDVTLEASRE SSKPRASLKP RKVCTGGKRR KDEISVDSLD FNKKILHTAW HPVDNVIAVA ATNNLYIFQD KIN
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.
  • 基因功能參考文獻:
    1. Results show that PPP2R2D expression was significantly upregulated at the mRNA and protein levels in gastric cancer (GC) tissues and correlated with poor prognosis. Further evidence demonstrates an oncogenic role of PPP2R2D in GC progression and development through regulation of mTOR. PMID: 29568966
    2. The PP2A regulatory subunit PPP2R2D inhibits T-cell proliferation and survival within tumors. PMID: 24596207
    3. The -462 G>A variant of PPP2R2D affects NF1 binding to the proximal promoter of PPP2R2D. PMID: 22539979
    4. These highly related members of the same subfamily of PP2A regulatory subunits differentially regulate TGF-beta/Activin/Nodal signalling to elicit opposing biological outcomes. PMID: 18697906
  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Phosphatase 2A regulatory subunit B family
  • 數據庫鏈接:

    HGNC: 23732

    OMIM: 613992

    KEGG: hsa:55844

    STRING: 9606.ENSP00000399970

    UniGene: Hs.380372



主站蜘蛛池模板: 97精品人妻一区二区三区香蕉| 9l国产精品久久久久麻豆| 少妇无码精油按摩专区 | 国产精品久久久久久久久久免费| 日韩精品人成在线播放| 国产乱人伦偷精品视频| 国产亚洲精品久久久久久小说| 国产制服丝袜亚洲高清| 色老头精品午夜福利视频| 亚洲乱码中文字幕手机在线| 在线精品国产一区二区三区| 亚洲国产成人无码网站大全| 艳妇乳肉豪妇荡乳av无码福利| 忍着娇喘人妻被中出中文字幕| 国产在线码观看超清无码视频| 好想被狂躁无码视频在线观看| 欧洲精品99毛片免费高清观看 | 国产草草影院ccyycom| 久久国产精品二国产精品| 日韩伦人妻无码| 国产免费无遮挡吸乳视频在线观看| 国产麻豆精品福利在线观看| 亚洲 国产 韩国 欧美 在线| 亚洲精品成人片在线观看精品字幕| 人妻无码中文字幕一区二区三区| 亚洲成在人网站无码天堂| 国产女人水真多18毛片18精品| 日韩一欧美内射在线观看| 俄罗斯大荫蒂女人毛茸茸| 香港曰本韩国三级网站| 无码超乳爆乳中文字幕| 狠狠热精品免费视频| 久久久久欧美国产高潮| 国产亚洲精品自在久久vr| 激情欧美成人久久综合| 国产av成人一区二区三区| 亚洲 精品 制服 校园 无码| 国产va免费精品观看| 国产精品久久久久影院亚瑟| 色五月激情五月| 综合三区后入内射国产馆|