在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Secretogranin-2 (SCG2)

Recombinant Human Secretogranin-2 (SCG2)

  • 中文名稱：
    人SCG2重組蛋白
  • 貨號：
    CSB-YP020808HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SCG2重組蛋白
  • 貨號：
    CSB-EP020808HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SCG2重組蛋白
  • 貨號：
    CSB-EP020808HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SCG2重組蛋白
  • 貨號：
    CSB-BP020808HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SCG2重組蛋白
  • 貨號：
    CSB-MP020808HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SCG2
  • Uniprot No.：
  • 別名：
    CHGC; Chromogranin C; Chromogranin-C; EM66; SCG2; SCG2_HUMAN; Secretogranin II; Secretogranin-2; Secretoneurin; SGII; SN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    31-617
  • 氨基酸序列
    QRNQLLQKEP DLRLENVQKF PSPEMIRALE YIENLRQQAH KEESSPDYNP YQGVSVPLQQ KENGDESHLP ERDSLSEEDW MRIILEALRQ AENEPQSAPK ENKPYALNSE KNFPMDMSDD YETQQWPERK LKHMQFPPMY EENSRDNPFK RTNEIVEEQY TPQSLATLES VFQELGKLTG PNNQKRERMD EEQKLYTDDE DDIYKANNIA YEDVVGGEDW NPVEEKIESQ TQEEVRDSKE NIEKNEQIND EMKRSGQLGI QEEDLRKESK DQLSDDVSKV IAYLKRLVNA AGSGRLQNGQ NGERATRLFE KPLDSQSIYQ LIEISRNLQI PPEDLIEMLK TGEKPNGSVE PERELDLPVD LDDISEADLD HPDLFQNRML SKSGYPKTPG RAGTEALPDG LSVEDILNLL GMESAANQKT SYFPNPYNQE KVLPRLPYGA GRSRSNQLPK AAWIPHVENR QMAYENLNDK DQELGEYLAR MLVKYPEIIN SNQVKRVPGQ GSSEDDLQEE EQIEQAIKEH LNQGSSQETD KLAPVSKRFP VGPPKNDDTP NRQYWDEDLL MKVLEYLNQE KAEKGREHIA KRAMENM
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
  • 基因功能參考文獻：
    1. Differential Reovirus-Specific and Herpesvirus-Specific Activator Protein 1 Activation of Secretogranin II Leads to Altered Virus Secretion. PMID: 26378181
    2. present data show that SgII is highly expressed in advanced prostate cancer and may contribute to the neuroendocrine differentiation by promoting the formation of secretory granules and the proliferation of PCa cells. PMID: 25307750
    3. SN induces MUC5AC hypersecretion in a dose- and time-dependent manner; moreover, the MUC5AC over synthesis induced by SN is strongly associated with the enhanced binding of EGF to NRP1 PMID: 24556756
    4. Topical secretoneurin gene therapy accelerates diabetic wound healing by interaction between heparan-sulfate proteoglycans and basic FGF. PMID: 23918206
    5. Manserin may serve as a marker of prostate cancer progression. PMID: 21803620
    6. CgA, CgB, and secretoneurin are detectable in feces, and collagenous colitis patients express higher values than patients with inflammatory bowel disease and controls. In treatment, fecal secretoneurin decreased to control levels in collagenous colitis. PMID: 23423580
    7. In vivo secretoneurin improves left ventricular function, inhibits remodeling, and reduces scar formation; in the infarct border zone, secretoneurin induces coronary angiogenesis. PMID: 23081990
    8. Circulating Levels of SgII are Increased in Patients with chronic, stable heart failure. PMID: 22655045
    9. Data describe the gene expression and protein production of SgII in normal adrenal glands and pheochromocytomas with the goal to examine the molecular mechanisms leading to the marked variations in the expression of EM66 in tumoral chromaffin tissue. PMID: 22217803
    10. This short review deals with investigations in neuroendocrine tumors (NETs) with antibodies against defined epitopes of chromogranins (Cgs) A and B and secretogranins (Sgs) II and III. PMID: 21046454
    11. More SgII immunoreactive cells were observed in phaeochromocytomas. PMID: 20550951
    12. Transendothelial migration of leukocytes and signalling mechanisms in response to the neuropeptide secretoneurin. PMID: 11853870
    13. secretogranin II-derived peptide EM66 generated in human tumoral chromaffin tissue; significant difference in EM66 concentrations between benign and malignant pheochromocytomas PMID: 12788858
    14. the high concentration of secretoneurin in the aqueous humor indicates a significant role of this peptide PMID: 15572199
    15. a variant of Secretogranin II has a role in regulation by PHOX2 transcription factors and in hypertension PMID: 17584765
    16. Results suggest that secretogranin II represents a key AP-1-regulated protein that counteracts nitric oxide toxicity and mediates neuronal differentiation of neuroblastoma cells. PMID: 18239671
    17. Increased concentrations of SgII, especially the N-terminal part of secretoneurin could be measured in plasma from patients with endocrine pancreatic tumours. PMID: 18448176
    18. Suppression of Pdcd4 resulted in an increased release of CgA and Sg II and was accompanied by an up-regulation of intracellular PC1. PMID: 18549351
    19. semiquantitative immunocytochemistry for secretogranin II in amyotrophic lateral sclerosis. PMID: 18721831

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted. Note=Neuroendocrine and endocrine secretory granules.
  • 蛋白家族：
    Chromogranin/secretogranin protein family
  • 數據庫鏈接：

    HGNC: 10575

    OMIM: 118930

    KEGG: hsa:7857

    STRING: 9606.ENSP00000304133

    UniGene: Hs.516726



主站蜘蛛池模板： 欧美无遮挡很黄裸交视频| 国产97人人超碰caoprom| 国产在线午夜不卡精品影院| 亚洲国产欧美日韩在线人成| 国产精品久久久| 亚洲精品久久久久久下一站| 男男女女爽爽爽免费视频| 国产精品18久久久久久欧美| 欧美超级乱婬视频播放| 51国产黑色丝袜高跟鞋| 久热在线这里只有精品国产| 国产一区二区三区不卡在线看 | 国产成人综合久久久久久| 国产av无码专区亚洲草草| 亚洲性无码av在线dvd| 九九久久精品无码专区| 永久免费观看美女裸体的网站 | 92精品成人国产在线观看| 精品欧美小视频在线观看| 国产丝袜美女| 久久伊人五月丁香狠狠色| 在线岛国片免费无码av| 亚洲国产制服丝袜高清在线| 美丽的熟妇中文字幕| 色五月丁香五月综合五月4438| 久久国产精品国产四虎90后| 国产综合久久亚洲综合| √最新版天堂资源网在线| 国产第一页浮力影院入口| 最新亚洲中文av在线不卡| 国产国产乱老熟女视频网站97| 7777精品久久久大香线蕉| 国产精品麻豆aⅴ人妻| 欧美性色黄大片手机版| 国产av麻豆mag剧集| 久久综合久久自在自线精品自| 性高朝久久久久久久久久| 欧美性大战久久久久久| 日本丰满少妇高潮呻吟| 天天躁日日躁狠狠躁性色av| 华人少妇被黑人粗大的猛烈进|