在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human SH3 and PX domain-containing protein 2B (SH3PXD2B), partial

Recombinant Human SH3 and PX domain-containing protein 2B (SH3PXD2B), partial

  • 中文名稱：
    人SH3PXD2B重組蛋白
  • 貨號：
    CSB-YP021240HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人SH3PXD2B重組蛋白
  • 貨號：
    CSB-EP021240HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人SH3PXD2B重組蛋白
  • 貨號：
    CSB-EP021240HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人SH3PXD2B重組蛋白
  • 貨號：
    CSB-BP021240HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人SH3PXD2B重組蛋白
  • 貨號：
    CSB-MP021240HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SH3PXD2B
  • Uniprot No.：
  • 別名：
    SH3PXD2B; FAD49; KIAA1295; TKS4; SH3 and PX domain-containing protein 2B; Adapter protein HOFI; Factor for adipocyte differentiation 49; Tyrosine kinase substrate with four SH3 domains
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Adapter protein involved in invadopodia and podosome formation and extracellular matrix degradation. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. Plays a role in mitotic clonal expansion during the immediate early stage of adipocyte differentiation.
  • 基因功能參考文獻：
    1. We report a sibling pair with Frank-ter Haar syndrome (FTHS) caused by a homozygous, novel mutation pLys133Glnfs*13 in the SH3PXD2B gene. PMID: 29100834
    2. Suggest the importance of Tks adaptor proteins in melanoma growth and metastasis in vivo is likely via functional invadopodia formation. PMID: 27802184
    3. Misfolded Frank-ter Haar syndrome protein Tks4(R43W) is transported via the microtubule system to the aggresomes. PMID: 26183326
    4. a new function for Tks4 in the regulation of growth factor-dependent cell migration. PMID: 22829589
    5. SH3PXD2B is a scaffold protein that plays a key role in regulating the actin cytoskeleton via Src and cortactin. PMID: 21886807
    6. Tks4 and Tks5 directly bind to NoxA1. The integrity of the N-terminal PRR of NoxA1 is essential for this direct interaction with the Tks proteins. PMID: 20609497
    7. The Nox1-dependent generation of reactive oxygen species is dependent on Src phosphorylation of NoxA1 and Tks4. Blockage of phosphorylation of NoxA1 and Tks4 decreases Nox1-dependent ROS generation and blocks SrcYF-induced invadopodia formation. PMID: 20943948
    8. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    9. These findings establish a role for TKS4 in Frank-Ter Haar syndrome and embryonic development. PMID: 20137777
    10. Observational study of gene-disease association. (HuGE Navigator) PMID: 19228371

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Frank-Ter Haar syndrome (FTHS)
  • 亞細胞定位：
    Cytoplasm. Cell projection, podosome.
  • 蛋白家族：
    SH3PXD2 family
  • 組織特異性：
    Expressed in fibroblasts.
  • 數據庫鏈接：

    HGNC: 29242

    OMIM: 249420

    KEGG: hsa:285590

    STRING: 9606.ENSP00000309714

    UniGene: Hs.285666



主站蜘蛛池模板： 在线观看无码不卡av中文| 韩日综合成人中文字幕| 香蕉久久人人97超碰caoproen| 一个人在线观看免费视频www| 国产肥白大熟妇bbbb| 夜夜爽夜夜叫夜夜高潮漏水| 免费看女人与善牲交| 亚洲国产精品无码久久久蜜芽| 嘿咻嘿咻男女免费专区| 少妇激情一区二区三区视频| 夜夜躁日日躁狠狠久久av| 色窝窝无码一区二区三区| 99re6热视频这里只精品首页| 久久亚洲国产精品亚洲老地址| 日本伦奷在线播放| 日本高清视频wwww色| 国产suv精品一区二区四| 久久久久99人妻一区二区三区| 欧美村妇激情内射| 欧美日韩精品成人网站二区| 欧美乱大交xxxxx疯狂俱乐部| 久久久久黑人强伦姧人妻| 国产精品久久久亚洲| 国产成人亚洲精品无码电影| 国产深夜福利视频在线| 999久久久免费精品国产| 国产av国片精品| 国产精品香港三级国产av| 久久久久亚洲精品天堂| 麻豆精品传媒一二三区艾秋| 亚洲精品一区二区三区四区五区| 婷婷五月婷婷五月| 国产v综合v亚洲欧| 亚洲欧美成人中文日韩电影网站| 天堂а在线中文在线新版| 尤物av无码色av无码| 黄网站成人片免费视频| 漂亮人妻被强中文字幕久久| 国产精品丝袜一区二区三区| 狂野av人人澡人人添| 老司机性色福利精品视频|