在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Recoverin (RCVRN)

In Stock
  • 中文名稱:
    人RCVRN重組蛋白
  • 貨號:
    CSB-YP019519HU
  • 規格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    RCVRN
  • Uniprot No.:
  • 別名:
    23 kDa photoreceptor cell-specific protein; Cancer associated retinopathy protein; Cancer-associated retinopathy protein; CAR; CAR protein; p26; Protein CAR; RCV1; RCVRN; RECO_HUMAN; Recoverin; S-modulin
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    Yeast
  • 分子量:
    25.0kDa
  • 表達區域:
    2-200aa
  • 氨基酸序列
    GNSKSGALSKEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMITPEDVKLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIEGTLANKEILRLIQFEPQKVKEKMKNA
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as a calcium sensor and regulates phototransduction of cone and rod photoreceptor cells. Modulates light sensitivity of cone photoreceptor in dark and dim conditions. In response to high Ca(2+) levels induced by low light levels, prolongs RHO/rhodopsin activation in rod photoreceptor cells by binding to and inhibiting GRK1-mediated phosphorylation of RHO/rhodopsin. Plays a role in scotopic vision/enhances vision in dim light by enhancing signal transfer between rod photoreceptors and rod bipolar cells. Improves rod photoreceptor sensitivity in dim light and mediates response of rod photoreceptors to facilitate detection of change and motion in bright light.
  • 基因功能參考文獻:
    1. High RCVRN expression is associated with renal tumors. PMID: 26813565
    2. Crystal Structure of Recoverin with Calcium Ions Bound to Both Functional EF Hands. PMID: 26584024
    3. C39D substitution reduces alpha-helical content, decreases thermal stability and suppresses membrane association. PMID: 21344177
    4. Aberrant hypomethylation of the recoverin gene region, overlapping the promoter up-stream of the first exon and the first exon itself, is involved in the aberrant expression of recoverin in tumor cells. PMID: 20812967
    5. recoverin has a pathological role in cancer-associated retinopathy PMID: 12596918
    6. There are cis-acting elements in the 5' non-coding region of the recoverin gene that are involved in the activation and suppression of gene expression. PMID: 12789533
    7. Human recoverin is expressed in SCLC cells cultured from an anti-recoverin antibody-negative patient with CAR. KK0206 might be important for further research on SCLC related retinopathy. PMID: 17374419
    8. A GRK1 region close to its C-terminus also seemed to be the binding site for S-modulin/recoverin. PMID: 18266817

    顯示更多

    收起更多

  • 亞細胞定位:
    Photoreceptor inner segment. Cell projection, cilium, photoreceptor outer segment. Photoreceptor outer segment membrane; Lipid-anchor; Cytoplasmic side. Perikaryon.
  • 蛋白家族:
    Recoverin family
  • 組織特異性:
    Retina and pineal gland.
  • 數據庫鏈接:

    HGNC: 9937

    OMIM: 179618

    KEGG: hsa:5957

    STRING: 9606.ENSP00000226193

    UniGene: Hs.80539



主站蜘蛛池模板: 亚洲国产欧美在线观看片不卡| 伊人久久大香线蕉综合直播| 久久精品成人免费国产片小草| 久久只精品99品免费久23| 免费观看全黄做爰大片国产| 国产产区一二三产区区别在线| 久久精品无码一区二区app| 九九久久精品国产免费看小说| 四虎影视在线观看2413| 亚洲精品456在线播放| 免费人成网站在线观看不卡| 天天天天噜在线视频| 亚洲国产另类久久久精品| 国产精品久久久久久久久久久不卡| 18禁无码永久免费无限制网站| 国产成人精品视频国产| 永久免费观看国产裸体美女| 色丁香婷婷综合久久| 在线不卡日本v二区到六区| av无码午夜福利一区二区三区| 欧美丰满熟妇bbb久久久| 丰满熟妇人妻中文字幕| 欧美亚洲综合成人专区| 日本高清无卡码一区二区 | 国产av一区二区三区| 成人做爰免费视频免费看| 一区二区伊人久久大杳蕉| 男人边吃奶边做好爽免费视频| 国内精品久久毛片一区二区| 四虎国产精品亚洲一区久久特色| 色悠久久久久综合先锋影音下载| 麻豆果冻传媒2021精品传媒一区 | 四虎成人永久在线精品免费| 国产一卡2卡3卡四卡精品app| 久久偷看各类wc女厕嘘嘘偷窃| 亚洲第一成人网站在线播放| 久久亚洲中文无码咪咪爱| 色欲av亚洲一区无码少妇| 人妻夜夜爽天天爽三区| 永久免费无码国产| 午夜无码国产理论在线|