在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Receptor-type tyrosine-protein phosphatase H (PTPRH), partial

Recombinant Human Receptor-type tyrosine-protein phosphatase H (PTPRH), partial

  • 中文名稱：
    人PTPRH重組蛋白
  • 貨號：
    CSB-YP864036HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人PTPRH重組蛋白
  • 貨號：
    CSB-EP864036HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人PTPRH重組蛋白
  • 貨號：
    CSB-EP864036HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人PTPRH重組蛋白
  • 貨號：
    CSB-BP864036HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人PTPRH重組蛋白
  • 貨號：
    CSB-MP864036HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    PTPRH
  • Uniprot No.：
  • 別名：
    BEM 2; BEM2; Brain-enriched membrane-associated protein tyrosine phosphatase 2; Phosphotyrosine phosphatase; Protein tyrosine phosphatase receptor type H; PTPASE; PTPRH; PTPRH_HUMAN; R-PTP-H; Receptor-type tyrosine-protein phosphatase H; SAP-1; SAP1; Stomach cancer-associated protein tyrosine phosphatase 1; Transmembrane-type protein tyrosine phosphatase H; Transmembrane-type protein-tyrosine phosphatase type H
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Protein phosphatase that may contribute to contact inhibition of cell growth and motility by mediating the dephosphorylation of focal adhesion-associated substrates and thus negatively regulating integrin-promoted signaling processes. Induces apoptotic cell death by at least two distinct mechanisms: inhibition of cell survival signaling mediated by PI 3-kinase, Akt, and ILK and activation of a caspase-dependent proapoptotic pathway. Inhibits the basal activity of LCK and its activation in response to TCR stimulation and TCR-induced activation of MAP kinase and surface expression of CD69. Inhibits TCR-induced tyrosine phosphorylation of LAT and ZAP70. Inhibits both basal activity of DOK1 and its CD2-induced tyrosine phosphorylation. Induces dephosphorylation of BCAR1, focal adhesion kinase and SRC. Reduces migratory activity of activity of Jurkat cells. Reduces tyrosine phosphorylation of CEACAM20 and thereby contributes to suppress the intestinal immune response CEACAM20.
  • 基因功能參考文獻：
    1. The results indicate that PTPRH is downregulated in colorectal tumors and its expression is epigenetically regulated via DNA methylation and chromatin modifications. PMID: 28713969
    2. PTPRH is overexpressed in non-small cell lung cancer, is regulated by DNA hypomethylation, and PTPRH DNA methylation was an independent prognostic factor PMID: 26134684
    3. SAP-1 induces apoptotic cell death by inhibition of cell survival signaling mediated by PI 3-kinase, Akt, and ILK and activation of a caspase-dependent proapoptotic pathway. PMID: 12101188
    4. SAP-1 expression is downregulated during the dedifferentiation of human hepatocellular carcinoma, which may play a causal role in disease progression PMID: 12879010
  • 亞細胞定位：
    Cell projection, microvillus membrane; Single-pass type I membrane protein. Apical cell membrane; Single-pass type I membrane protein. Cytoplasm.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Receptor class 3 subfamily
  • 組織特異性：
    Expressed at high levels in the brain, spleen and liver and at lower levels in the heart and stomach. Expressed in pancreatic and colorectal cancer cells, but not in normal pancreas or colon. Expression in hepatocellular carcinoma is related to the differ
  • 數據庫鏈接：

    HGNC: 9672

    OMIM: 602510

    STRING: 9606.ENSP00000365528

    UniGene: Hs.179770



主站蜘蛛池模板： 国内精品无码一区二区三区| 上司人妻互换中文字幕| 精品无码一区二区三区在线| 成在人av抽搐高潮喷水流白浆| 亚洲 欧美 日产 综合 在线| 在线精品国产大象香蕉网| 色天使久久综合网天天| 成人午夜高潮a∨猛片| 国产在线看片免费人成视频| 久久久婷婷五月亚洲97色| 欧美国产日韩a在线视频下载| а天堂中文最新一区二区三区| 综合网日日天干夜夜久久| 国产精品女同一区二区| 亚洲国产精品国自产拍电影| 欧美成人aaaa免费全部观看 | 美女露出粉嫩小奶头在视频18禁| 免费无码又爽又刺激高潮的视频| 国产婷婷成人久久av免费高清| 欧洲女人牲交性开放视频| 欧美黑人激情性久久| 五月丁香啪啪| 免费观看又污又黄在线观看| 精品国产av无码一区二区三区| 亚洲精品电影院| 欧美乱大交aaaa片if| 亚洲乱色熟女一区二区三区丝袜| 中国女人内谢69xxxx视频| 男女又色又爽又爽视频| 成年动漫18禁无码3d动漫| 欧美毛多水多肥妇| 欧美颜射内射中出口爆在线| 人与动人物xxxx毛片人与狍| 亚洲色在线无码国产精品| 狠狠噜天天噜日日噜视频麻豆| 精品香蕉一区二区三区| 精品国产综合成人亚洲区| 欧美性猛交xxxx三人| 少妇爆乳无码专区| 国产乱子经典视频在线观看| 国产成久久免费精品av片|