在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human RecQ-mediated genome instability protein 2 (RMI2)

Recombinant Human RecQ-mediated genome instability protein 2 (RMI2)

  • 中文名稱：
    人RMI2重組蛋白
  • 貨號：
    CSB-YP839311HU
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人RMI2重組蛋白
  • 貨號：
    CSB-EP839311HU
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人RMI2重組蛋白
  • 貨號：
    CSB-EP839311HU-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人RMI2重組蛋白
  • 貨號：
    CSB-BP839311HU
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人RMI2重組蛋白
  • 貨號：
    CSB-MP839311HU
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    RMI2
  • Uniprot No.：
  • 別名：
    BLAP18; BLM-associated protein of 18 kDa; C16orf75; hRMI2; MGC24665; RecQ-mediated genome instability protein 2; RMI2; RMI2_HUMAN
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-147
  • 氨基酸序列
    AAAADSFSG GPAGVRLPRS PPLKVLAEQL RRDAEGGPGA WRLSRAAAGR GPLDLAAVWM QGRVVMADRG EARLRDPSGD FSVRGLERVP RGRPCLVPGK YVMVMGVVQA CSPEPCLQAV KMTDLSDNPI HESMWELEVE DLHRNIP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM.
  • 基因功能參考文獻：
    1. In both patient and knockout cell lines reduced localisation of BLM to ultra fine DNA bridges and FANCD2 at foci linking bridges are observed. Overall, loss of RMI2 produces a partially active BLM complex with mild features of Bloom syndrome. PMID: 27977684
  • 相關疾病：
    A homozygous deletion of RMI2 has been found in a family with a Bloom-like syndrome and is probable responsible for the phenotype. Patients manifest depigmented skin lesions, multiple cafe-au-lait macules, and growth deficiency. Cells from affected individuals show a high rate of sister chromatid exchange and increased chromosomal breaks.
  • 亞細胞定位：
    Nucleus. Note=Colocalizes with BLM at nuclear DNA repair foci.
  • 蛋白家族：
    RMI2 family
  • 數據庫鏈接：

    HGNC: 28349

    OMIM: 612426

    KEGG: hsa:116028

    STRING: 9606.ENSP00000310356

    UniGene: Hs.347524



主站蜘蛛池模板： 无码国产片观看| 国产日韩综合一区在线观看| 久久久久四虎精品免费入口| 无码av专区丝袜专区| 欧美黑人巨大videos精品| 少妇高潮喷水久久久久久久久久| 国产精品无码翘臀在线观看| 99久久精品免费看国产一区二区三区 | 国产精品自产拍高潮在线观看 | 国精品午夜福利视频导航| 欧美精品九九久久久久久久久 | 日韩av无码成人无码免费| 挺进邻居丰满少妇的身体| 亚洲欧美日韩国产成人一区| 午夜福利日本一区二区无码| 1000部夫妻午夜免费| 久久久久久综合网天天| 丰满的人妻hd高清日本| 色综合天天无码网站| 人人澡人人妻人人爽人人蜜桃麻豆| 久久国产加勒比精品无码| 鲁大师在线视频播放免费观看| 久久精品中文闷骚内射| 奇米四色7777中文字幕| 五月天天天综合精品无码| 久久欧美一区二区三区性生奴| 国产精品久久福利网站| 亚洲高清专区日韩精品| 正在播放国产剧情亂倫| 日日噜噜夜夜爽爽| 中文幕无线码中文字夫妻| 免费看女人与善牲交| 亚洲中文在线精品国产| 色偷偷亚洲男人本色| 午夜理论在线观看不卡大地影院| 人妻老妇乱子伦精品无码专区| 四虎成人精品一区二区免费网站| 亚洲亚洲人成综合网络| 午夜理论在线观看不卡大地影院| 成人无码专区免费播放三区| 亚洲熟妇丰满大屁股熟妇|