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  4. Recombinant Human Ras association domain-containing protein 3 (RASSF3)

Recombinant Human Ras association domain-containing protein 3 (RASSF3)

  • 中文名稱：
    人RASSF3重組蛋白
  • 貨號：
    CSB-YP801247HU
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    人RASSF3重組蛋白
  • 貨號：
    CSB-EP801247HU
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    人RASSF3重組蛋白
  • 貨號：
    CSB-EP801247HU-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    人RASSF3重組蛋白
  • 貨號：
    CSB-BP801247HU
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    人RASSF3重組蛋白
  • 貨號：
    CSB-MP801247HU
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    RASSF3
  • Uniprot No.：
  • 別名：
    MGC119194; MGC119195; MGC119197; Ras association (RalGDS/AF 6) domain family 3; Ras association domain containing protein 3; Ras association domain-containing protein 3; RASF3_HUMAN; Rassf3
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-238
  • 氨基酸序列
    SSGYSSLEE DAEDFFFTAR TSFFRRAPQG KPRSGQQDVE KEKETHSYLS KEEIKEKVHK YNLAVTDKLK MTLNSNGIYT GFIKVQMELC KPPQTSPNSG KLSPSSNGCM NTLHISSTNT VGEVIEALLK KFLVTESPAK FALYKRCHRE DQVYACKLSD REHPLYLRLV AGPRTDTLSF VLREHEIGEW EAFSLPELQN FLRILDKEED EQLQNLKRRY TAYRQKLEEA LREVWKPD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. low expression is associated with malignant phenotypes in non-small cell lung cancer patients PMID: 24246507
    2. Taken together, these findings indicate that the RASSF3 promoter rs6581580 T>G SNP is potentially functional, modulating susceptibility to SCCHN among non-Hispanic whites. PMID: 24295637
    3. hypermethylation-induced RASSF3 silencing plays an important role in the tumorigenesis of pituitary somatotroph adenomas. PMID: 23555615
    4. tumor suppressor activity of RASSF3, which occurs through p53 stabilization and regulation of apoptosis and the cell cycle. PMID: 22593196
    5. Observational study of gene-disease association. (HuGE Navigator) PMID: 20237496
    6. Mammary tumor incidence in bi-transgenic mice is delayed, suggesting that transgenic Rassf3 may influence mammary tumor incidence in transgenic mice PMID: 19148488
    7. The presence of a Ras association domain common to NORE1,RASSF1, and RASSF3 suggests their possible involvement inRas-like signaling pathways. PMID: 11965544

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  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Note=Localized to microtubules in vascular endothelial cells.
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 14271

    OMIM: 607019

    KEGG: hsa:283349

    STRING: 9606.ENSP00000336616

    UniGene: Hs.643605



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