Recombinant Human RNMT-activating mini protein (FAM103A1)

中文名稱：

人FAM103A1重組蛋白
貨號：

CSB-YP874806HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人FAM103A1重組蛋白
貨號：

CSB-EP874806HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人FAM103A1重組蛋白
貨號：

CSB-EP874806HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人FAM103A1重組蛋白
貨號：

CSB-BP874806HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人FAM103A1重組蛋白
貨號：

CSB-MP874806HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

FAM103A1
Uniprot No.：

Q9BTL3
別名：

RAMAC; C15orf18; FAM103A1; RAMMET; RNA guanine-N7 methyltransferase activating subunit; Protein FAM103A1; RNA guanine-7 methyltransferase activating subunit; RNMT-activating mRNA cap methyltransferase subunit; RNMT-activating mini protein; RAM
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-118
氨基酸序列

TDTAEAVPK FEEMFASRFT ENDKEYQEYL KRPPESPPIV EEWNSRAGGN QRNRGNRLQD NRQFRGRDNR WGWPSDNRSN QWHGRSWGNN YPQHRQEPYY PQQYGHYGYN QRPPYGYY
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Regulatory subunit of the mRNA-capping methyltransferase RNMT:RAMAC complex that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Promotes the recruitment of the methyl donor, S-adenosyl-L-methionine, to RNMT. Regulates RNMT expression by a post-transcriptional stabilizing mechanism. Binds RNA.
基因功能參考文獻：
1. RNMT-RAM complex coordinates mRNA processing with ribosome production. PMID: 27934633
2. Data suggest that RAM/FAM103A1 has three domains: N-terminal activation domain (RAD); central RNA-binding domain (NR domain); and C-terminal nuclear localization domain (QYP) which contains two nuclear localization signal sequences. PMID: 24200467
3. RAM is an essential component of the core gene expression machinery PMID: 22099306
亞細胞定位：

Nucleus.
蛋白家族：

RAM family
數據庫鏈接：

HGNC: 31022

OMIM: 614547

KEGG: hsa:83640

STRING: 9606.ENSP00000307181

UniGene: Hs.80624