在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human RING finger protein 186 (RNF186), partial

  • 中文名稱:
    人RNF186重組蛋白
  • 貨號:
    CSB-YP019864HU1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人RNF186重組蛋白
  • 貨號:
    CSB-EP019864HU1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人RNF186重組蛋白
  • 貨號:
    CSB-EP019864HU1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人RNF186重組蛋白
  • 貨號:
    CSB-BP019864HU1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人RNF186重組蛋白
  • 貨號:
    CSB-MP019864HU1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    RNF186
  • Uniprot No.:
  • 別名:
    RNF186; E3 ubiquitin-protein ligase RNF186; RING finger protein 186
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    E3 ubiquitin protein ligase that is part of an apoptotic signaling pathway activated by endoplasmic reticulum stress. In that process, stimulates the expression of proteins specific of the unfolded protein response (UPR), ubiquitinates BNIP1 and regulates its localization to the mitochondrion and induces calcium release from the endoplasmic reticulum that ultimately leads to cell apoptosis.
  • 基因功能參考文獻:
    1. a predicted protein-truncating variant (rs36095412, p.R179X, genotyped in 11,148 ulcerative colitis patients and 295,446 controls, MAF=up to 0.78%) in RNF186, a single-exon ring finger E3 ligase with strong colonic expression, protects against ulcerative colitis. PMID: 27503255
    2. Our results confirmed significant association to rare non-synonymous coding variants in both IL23R and CARD9, previously identified from sequencing of CD loci, as well as identified a novel association in RNF186 PMID: 24068945
    3. BNip1 functions as a downstream modulator of RNF186 to direct endoplasmic reticulum stress-associated apoptotic signaling. PMID: 23896122
    4. Single-nucleotide polymorphism in RNF186 gene is associated with ulcerative colitis. PMID: 23511034
  • 亞細胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 數據庫鏈接:

    HGNC: 25978

    KEGG: hsa:54546

    STRING: 9606.ENSP00000364263

    UniGene: Hs.124835



主站蜘蛛池模板: av片在线观看永久免费| 国产日产欧产精品精品| 久久伊99综合婷婷久久伊| 老司机久久99久久精品播放免费| 少妇熟女久久综合网色欲| 99偷拍视频精品一区二区| 国产熟女一区二区三区四区五区 | 欧美三级欧美成人高清| 国产重口老太和小伙乱| 久久久久亚洲精品成人网| av免费网址在线观看| 在线中文新版最新版在线| 欧美性video高清精品| 无码av永久免费专区麻豆| 青青草国产成人99久久| 医院人妻闷声隔着帘子被中出 | 欧美黑人激情性久久| 欧美乱人伦人妻中文字幕| 中国熟妇牲交视频| 欧美处交wwwvideos另类| 内射白嫩少妇超碰| 国产精品www夜色视频| 伊人久久大香线蕉av波多野结衣| 国产人在线成免费视频| 中国极品少妇videossexhd| 人人妻人人澡人人爽欧美一区| 欧美成aⅴ人高清免费| 大胆日本熟妇xxxx| 亚洲aⅴ天堂av天堂无码麻豆| 欧美成人精品高清在线播放| 国产超碰人人做人人爽av大片| 中文字幕有码无码人妻av蜜桃| 日本三级成本人网站| 中文字幕无码人妻丝袜| 久久99精品国产99久久6不卡| 3d动漫精品啪啪一区二区免费 | 国产女精品视频网站免费| 日本午夜精品一区二区三区电影| 亚洲无线码免费| 无码粉嫩虎白一线天在线观看| 精品久久久久久无码人妻蜜桃|