在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Pyrroline-5-carboxylate reductase 2 (PYCR2)

  • 中文名稱:
    人PYCR2重組蛋白
  • 貨號:
    CSB-YP822188HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PYCR2重組蛋白
  • 貨號:
    CSB-EP822188HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PYCR2重組蛋白
  • 貨號:
    CSB-EP822188HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PYCR2重組蛋白
  • 貨號:
    CSB-BP822188HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PYCR2重組蛋白
  • 貨號:
    CSB-MP822188HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PYCR2
  • Uniprot No.:
  • 別名:
    1810018M05Rik; FLJ54750; Leftb; OTTHUMP00000035614; P5C reductase 2; P5CR 2; P5CR2; P5CR2_HUMAN; PYCR 2; PYCR2; Pyrroline 5 carboxylate reductase 2; Pyrroline 5 carboxylate reductase family member 2; Pyrroline 5 carboxylate reductase isoform; Pyrroline-5-carboxylate reductase 2; RP4-559A3.4
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-320
  • 氨基酸序列
    SVGFIGAGQ LAYALARGFT AAGILSAHKI IASSPEMNLP TVSALRKMGV NLTRSNKETV KHSDVLFLAV KPHIIPFILD EIGADVQARH IVVSCAAGVT ISSVEKKLMA FQPAPKVIRC MTNTPVVVQE GATVYATGTH ALVEDGQLLE QLMSSVGFCT EVEEDLIDAV TGLSGSGPAY AFMALDALAD GGVKMGLPRR LAIQLGAQAL LGAAKMLLDS EQHPCQLKDN VCSPGGATIH ALHFLESGGF RSLLINAVEA SCIRTRELQS MADQEKISPA ALKKTLLDRV KLESPTVSTL TPSSPGKLLT RSLALGGKKD
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH. Involved in cellular response to oxidative stress.
  • 基因功能參考文獻:
    1. PYCR2-related syndrome represents a clinically recognizable condition in which PYCR2 mutations lead to protein dysfunction. PMID: 27130255
    2. It was found that silence of PYCR2 resulted in the decrease of proliferative ability and activation of AMPK/mTOR-induced autophagy of A375 cells. PYCR2 silencing also activated AMPK/mTOR pathway in another melanoma cell line, CHL-1. PMID: 26634742
    3. Silencing of both PYCR1 and PYCR2 completely abolished anti-oxidation activity of RRM2B, demonstrating a functional collaboration of these metabolic enzymes in response to oxidative stress. PMID: 26733354
    4. Hypomyelination and the absence of lax caused by previously reported mutations in the gene encoding PYCR2's isozyme, PYCR1, suggesting a unique and indispensable role for PYCR2 in the human CNS during development. PMID: 25865492
  • 相關疾病:
    Leukodystrophy, hypomyelinating, 10 (HLD10)
  • 亞細胞定位:
    Cytoplasm. Mitochondrion.
  • 蛋白家族:
    Pyrroline-5-carboxylate reductase family
  • 組織特異性:
    Detected in erythrocytes (at protein level). Expressed in fetal brain.
  • 數據庫鏈接:

    HGNC: 30262

    OMIM: 616406

    KEGG: hsa:29920

    STRING: 9606.ENSP00000342502

    UniGene: Hs.654718



主站蜘蛛池模板: 免费无码国产v片在线观看| 啪啪激情婷婷久久婷婷色五月| 免费大片av手机看片不卡| 九九视频免费精品视频| 国产午夜福利精品久久2021| 色噜噜狠狠狠综合曰曰曰| 中文无码一区二区不卡αv| 亚洲国产精品国自产拍av| 欧美18精品久久久无码午夜福利| 国产又爽又黄又刺激的视频| 无码一区二区免费波多野播放搜索| 国产成人无码aa精品一区| 欧洲成人一区二区三区| 加勒比无码人妻东京热| 久久激情综合狠狠爱五月| 中文字幕乱码熟妇五十中出色欲 | 国产精品自在线拍国产| 无码8090精品久久一区| 综合亚洲综合图区网友自拍| 精品av无码国产一区二区| 国产寡妇偷人在线观看| 亚洲成在人网站无码天堂| 亚洲国产成人久久综合| 国产偷人妻精品一区| 国产精品点击进入在线影院高清| 青椒国产97在线熟女| 精品国产福利拍拍拍| 亚洲人成电影在线观看影院| 欧美综合自拍亚洲综合图片区| 国产精品嫩草影院免费观看| 久久精品日韩av无码| 午夜片无码区私人影院| 肉大捧一进一出免费视频| 少妇高潮无套内谢麻豆传| 久久精品无码av| 国产精品久久久久野外| 老师黑色丝袜被躁翻了av| 漂亮人妻被强中文字幕久久| 亚洲www啪成人一区二区麻豆| 欧洲日韩亚洲无线在码| 国产日韩综合av在线观看一区 |