在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Pyridoxal kinase (PDXK)

  • 中文名稱:
    人PDXK重組蛋白
  • 貨號:
    CSB-YP017748HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PDXK重組蛋白
  • 貨號:
    CSB-EP017748HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PDXK重組蛋白
  • 貨號:
    CSB-BP017748HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PDXK重組蛋白
  • 貨號:
    CSB-MP017748HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PDXK
  • Uniprot No.:
  • 別名:
    pdxK; PDXK_HUMAN; PKH; PNK ; Pyridoxal kinase; Pyridoxamine kinase; Pyridoxine kinase; Pyridoxine kinase,; Vitamin B6 kinase
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-312
  • 氨基酸序列
    MEEECRVLSI QSHVIRGYVG NRAATFPLQV LGFEIDAVNS VQFSNHTGYA HWKGQVLNSD ELQELYEGLR LNNMNKYDYV LTGYTRDKSF LAMVVDIVQE LKQQNPRLVY VCDPVLGDKW DGEGSMYVPE DLLPVYKEKV VPLADIITPN QFEAELLSGR KIHSQEEALR VMDMLHSMGP DTVVITSSDL PSPQGSNYLI VLGSQRRRNP AGSVVMERIR MDIRKVDAVF VGTGDLFAAM LLAWTHKHPN NLKVACEKTV STLHHVLQRT IQCAKAQAGE GVRPSPMQLE LRMVQSKRDI EDPEIVVQAT VL
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (Probable). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions.
  • 基因功能參考文獻:
    1. The affected pyridoxine metabolism is discussed as an inborn genetic trait in epilepsy in general, rather than a specific sign of pyridoxine-dependent epilepsy solely. PMID: 22647618
    2. The pyridoxal kinase showed decreased levels and was highly carbonylated in the gene-on mice PMID: 20639122
    3. This study identified a DNA variant (rs2010795) in PDXK associated with an increased risk of PD in the German cohort This association was confirmed in the British and Italian cohorts individually and reached a combined value. PMID: 20035503
    4. Pyridoxal kinase expression was compared in fetal Down syndrome (DS) brain and controls; PDXK levels were found to be similar. PMID: 15082224
    5. A promoter mutation with potential erythroid-specific properties that could be the basis of a novel mechanism of controlling cell-specific decreased activity of an essential enzyme in erythrocytes. PMID: 16704963
    6. The crystal structure of the MgATP complex also reveals Mg(2+) and Na(+) acting in tandem to anchor the ATP at the active site of pyridoxal kinase. PMID: 17766369
    7. These results document the role of Asp235 in PL kinase activity. PMID: 19351586

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytosol.
  • 蛋白家族:
    Pyridoxine kinase family
  • 組織特異性:
    Ubiquitous. Highly expressed in testis.; [Isoform 3]: In adult testis and spermatozoa.
  • 數據庫鏈接:

    HGNC: 8819

    OMIM: 179020

    KEGG: hsa:8566

    STRING: 9606.ENSP00000291565

    UniGene: Hs.284491



主站蜘蛛池模板: 男女做爰猛烈叫床视频动态图| 日本强伦片中文字幕免费看| 国产成 人 综合 亚洲专区| 色94色欧美sute亚洲线路一| 欧美无人区码suv| 国产成人三级一区二区在线观看一| 熟妇人妻午夜寂寞影院| 夜夜澡天天碰人人爱av| 国产日产精品一区二区三区四区的特点| 亚洲欧美日韩在线不卡| 国产熟妇高潮呻吟喷水| aaa午夜级特黄日本大片| 久久精品亚洲中文字幕无码网站| 国产成人精品亚洲午夜麻豆| 午夜影视啪啪免费体验区入口| 国产亚洲精品岁国产微拍精品| 国产精品美女久久久久av爽李琼| 青青青伊人色综合久久| 少妇白浆呻吟爽| 国产日韩在线观看不卡顿| 午夜成人鲁丝片午夜精品| 精品国产不卡一区二区三区| 丰满的少妇xxxxx人| 国产精品人妻一区二区高| 又爽又黄又无遮挡的视频| 医院人妻闷声隔着帘子被中出| 又黄又湿免费高清视频| av午夜福利一片免费看久久| 国产内射合集颜射| 日日摸天天摸人人看| 亚洲精品国产精品乱码不卡√| √最新版天堂资源网在线| 国产99在线 | 免费| 国产精品自在拍首页视频8| 亚洲精品夜夜夜| 无码av片av片av无码| 免费人成在线观看网站品爱网| 亚洲国产精品综合久久20| 最近中文2019字幕第二页| 狠狠色噜噜狠狠狠狠米奇777| 大白肥妇bbvbbw高潮|