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Recombinant Human Putative lipoyltransferase 2, mitochondrial (LIPT2)

  • 中文名稱:
    人LIPT2重組蛋白
  • 貨號:
    CSB-YP411461HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人LIPT2重組蛋白
  • 貨號:
    CSB-EP411461HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人LIPT2重組蛋白
  • 貨號:
    CSB-EP411461HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人LIPT2重組蛋白
  • 貨號:
    CSB-BP411461HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人LIPT2重組蛋白
  • 貨號:
    CSB-MP411461HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    LIPT2
  • Uniprot No.:
  • 別名:
    LIPT2; Putative lipoyltransferase 2; mitochondrial; EC 2.3.1.181; Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區(qū)域:
    32-231
  • 氨基酸序列
    AEPGIEAPS GTEAGALLLC EPAGPVYTAG LRGGLTPEET ARLRALGAEV RVTGRGGLAT FHGPGQLLCH PVLDLRRLGL RLRMHVASLE ACAVRLCELQ GLQDARARPP PYTGVWLDDR KICAIGVRCG RHITSHGLAL NCSTDLTWFE HIVPCGLVGT GVTSLSKELQ RHVTVEEVMP PFLVAFKEIY KCTLISEDSP N
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes, which catalyze essential redox reactions. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
  • 基因功能參考文獻:
    1. The authors report on the identification of biallelic LIPT2 mutations in three affected individuals from two families with severe neonatal encephalopathy where a normalization of lipoylation was observed after expression of wild-type LIPT2, arguing for LIPT2 requirement in intramitochondrial lipoate synthesis. PMID: 28757203
    2. Observational study of gene-disease association. (HuGE Navigator) PMID: 20877624
  • 相關疾病:
    Encephalopathy, neonatal severe, with lactic acidosis and brain abnormalities (NELABA)
  • 亞細胞定位:
    Mitochondrion.
  • 蛋白家族:
    LipB family
  • 數據庫鏈接:

    HGNC: 37216

    OMIM: 617659

    KEGG: hsa:387787

    STRING: 9606.ENSP00000309463

    UniGene: Hs.591971



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