在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein phosphatase 1 regulatory subunit 3C (PPP1R3C)

  • 中文名稱:
    人PPP1R3C重組蛋白
  • 貨號:
    CSB-YP891803HU
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PPP1R3C重組蛋白
  • 貨號:
    CSB-EP891803HU
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PPP1R3C重組蛋白
  • 貨號:
    CSB-EP891803HU-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PPP1R3C重組蛋白
  • 貨號:
    CSB-BP891803HU
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PPP1R3C重組蛋白
  • 貨號:
    CSB-MP891803HU
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    OTTHUMP00000020089; Phosphatase 1, regulatory inhibitor subunit 5; PP1 subunit R5; ppp1r3c; PPP1R5; PPR3C_HUMAN; Protein phosphatase 1 inhibitor 3C; Protein phosphatase 1 regulatory subunit 3C; Protein phosphatase 1 regulatory subunit 5; protein phosphatase 1, regulatory (inhibitor) subunit 3C; Protein targeting to glycogen; PTG; R5
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-317
  • 氨基酸序列
    MSCTRMIQVL DPRPLTSSVM PVDVAMRLCL AHSPPVKSFL GPYDEFQRRH FVNKLKPLKS CLNIKHKAKS QNDWKCSHNQ AKKRVVFADS KGLSLTAIHV FSDLPEEPAW DLQFDLLDLN DISSALKHHE EKNLILDFPQ PSTDYLSFRS HFQKNFVCLE NCSLQERTVT GTVKVKNVSF EKKVQIRITF DSWKNYTDVD CVYMKNVYGG TDSDTFSFAI DLPPVIPTEQ KIEFCISYHA NGQVFWDNND GQNYRIVHVQ WKPDGVQTQM APQDCAFHQT SPKTELESTI FGSPRLASGL FPEWQSWGRM ENLASYR
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.
  • 基因功能參考文獻:
    1. PPP1R3C, a novel hypermethylated gene in colorectal cancer, may play a critical role in cancer cell growth in association with glucose levels. PMID: 25846879
    2. detection of methylation of PPP1R3C alone or in combination with EFHD1 in plasma DNA showed high sensitivity and specificity in CRC detection, and may be useful detection method for CRC, especially for early-stage CRCs. PMID: 24861485
    3. Findings suggest that variations in PTG may condition the course of Lafora disease and establish PTG as a potential target for pharmacogenetic and therapeutic approaches. PMID: 21738631
    4. Results demonstrated that HIF1 promotes glycogen accumulation through regulating PPP1R3C expression under hypoxia, which revealed a novel metabolic adaptation of cells to hypoxia. PMID: 20888814
    5. phosphorylation of R5/PTG at Ser-8 by AMPK accelerates its laforin/malin-dependent ubiquitination and subsequent proteasomal degradation, which results in a decrease of its glycogenic activity. PMID: 19171932

    顯示更多

    收起更多

  • 數據庫鏈接:

    HGNC: 9293

    OMIM: 602999

    KEGG: hsa:5507

    STRING: 9606.ENSP00000238994

    UniGene: Hs.303090



主站蜘蛛池模板: 玩弄人妻少妇500系列视频| 久久精品国产69国产精品亚洲 | 亚洲一本大道av久在线播放| 伊人久久丁香色婷婷啪啪| 国产成人精品亚洲精品| 精品欧美一区二区三区久久久| 成 人影片 免费观看| 亚洲欧洲无码av电影在线观看| 日韩午夜理论片 中文字幕| 日本边添边摸边做边爱| 国产午夜伦鲁鲁| 亚洲成a∧人片在线观看无码| 欲妇荡岳丰满少妇岳| 国产无遮挡吃胸膜奶免费看| 国模少妇一区二区三区| 精品国产你懂的在线观看| 精品亚洲国产成人av不卡| 国产免费永久精品无码| 韩国三级在线观看久| 久久综合九色欧美婷婷| 国产成人无码18禁午夜福利网址| 亚洲精品av一区在线观看| 日本中文字幕亚洲乱码| 亚洲欧美精品伊人久久| 国产成人毛片在线视频软件| 一区二三区在线 | 中国| 国精品无码一区二区三区左线| 免费观看性行为视频的网站 | 国产成人精品日本亚洲18| 欧美乱人伦视频在线| 亚洲 a v无 码免 费 成 人 a v | 色悠久久久久综合欧美99| 中文字幕亚洲男人的天堂网络 | 国产精品无码制服丝袜| 婷婷色香合缴缴情av第三区| 欧美老肥熟妇多毛xxxxx| 欧洲人妻丰满av无码久久不卡| 国产又大又粗又爽的毛片| 美女人妻激情乱人伦| 顶级少妇做爰视频在线观看| 日本电影一区二区三区|