在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein phosphatase 1 regulatory subunit 1A (PPP1R1A)

  • 中文名稱:
    人PPP1R1A重組蛋白
  • 貨號:
    CSB-YP613409HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PPP1R1A重組蛋白
  • 貨號:
    CSB-EP613409HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PPP1R1A重組蛋白
  • 貨號:
    CSB-EP613409HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PPP1R1A重組蛋白
  • 貨號:
    CSB-BP613409HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PPP1R1A重組蛋白
  • 貨號:
    CSB-MP613409HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PPP1R1A
  • Uniprot No.:
  • 別名:
    I 1; I-1; I1; Inhibitor 1; IPP 1; IPP-1; IPP1; Ppp1r1a; PPR1A_HUMAN; Protein phosphatase 1 regulatory (inhibitor) subunit 1A; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase inhibitor 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-171
  • 氨基酸序列
    MEQDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI DEDRIPNPHL KSTLAMSPRQ RKKMTRITPT MKELQMMVEH HLGQQQQGEE PEGAAESTET QESRPPGIPD TEVESRLGTS GTAKKTAECI PKTHERGSKE PSTKEPSTHI PPLDSKGANS V
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
  • 基因功能參考文獻:
    1. These findings suggest that the human G109E inhibitor-1 variant impairs sarcoplasmic reticulum Ca-cycling and promotes arrhythmogenesis under stress conditions. PMID: 26455482
    2. I-1 and sarco/endoplasmic reticulum Ca2+ -ATPase synergistically induce the vascular smooth muscle cell contractile phenotype. PMID: 24249716
    3. multiple domains in I-1 target cellular PP1 complexes, and I-1 has a role as a cellular regulator of eIF2alpha phosphorylation PMID: 15345721
    4. G147D PPI-1 can attenuate responses of cardiomyocytes to beta-adrenergic agonists by decreasing PLN phosphorylation and therefore may contribute to deteriorated function in heart failure. PMID: 18192322
    5. the human inhibitor-1 G147D polymorphism, found almost exclusively in blacks, may act as a modifier rather than risk factor in heart failure development PMID: 18698139

    顯示更多

    收起更多

  • 蛋白家族:
    Protein phosphatase inhibitor 1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 9286

    OMIM: 613246

    KEGG: hsa:5502

    STRING: 9606.ENSP00000257905

    UniGene: Hs.505662



主站蜘蛛池模板: 夜精品a片一区二区三区无码白浆 漂亮人妻被中出中文字幕 | 午夜三级a三级三点在线观看| 波多野结衣初尝黑人| 国产男女猛烈无遮挡a片漫画| 色婷婷综合久久久久中文字幕 | 强伦姧人妻免费无码电影| 国产成人18黄网站| 中文天堂资源在线www| av在线播放无码线| 天天天天做夜夜夜夜做无码| 成人a毛片视频免费看| 亚洲人成网7777777国产| 男女裸交免费无遮挡全过程| 久久无码潮喷a片无码高潮| 欧美裸体xxxx极品| 特大黑人娇小亚洲女| 国产精品毛片一区二区| 亚洲欧美国产另类va| 中文字幕无码中文字幕有码a| 内射精品无码中文字幕| 日日狠狠久久8888偷偷色| 黄网站成人片免费视频| 久久久国产99久久国产久一| 亚洲人成伊人成综合网久久久| 一出一进一爽一粗一大视频| 中文字幕熟妇人妻在线视频| 久久精品中文字幕第一页| 性少妇无码播放| 乱码午夜-极品国产内射| 国产欧洲精品自在自线官方| 天堂中文在线8最新版地址| 国产激情久久久久久熟女老人 | 宅男宅女精品国产av天堂| 久热这里只有精品12| 国模无码大尺度一区二区三区 | 丁香五月激情综合国产| 波多野结衣免费一区视频| 男受被做哭激烈娇喘gv视频| 国内精品久久久久久影院| 少妇人妻陈艳和黑人教练| 日本不卡一区二区三区|