在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Protein phosphatase 1 regulatory subunit 1A (PPP1R1A)

  • 中文名稱:
    人PPP1R1A重組蛋白
  • 貨號:
    CSB-YP613409HU
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    人PPP1R1A重組蛋白
  • 貨號:
    CSB-EP613409HU
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    人PPP1R1A重組蛋白
  • 貨號:
    CSB-EP613409HU-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    人PPP1R1A重組蛋白
  • 貨號:
    CSB-BP613409HU
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    人PPP1R1A重組蛋白
  • 貨號:
    CSB-MP613409HU
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    PPP1R1A
  • Uniprot No.:
  • 別名:
    I 1; I-1; I1; Inhibitor 1; IPP 1; IPP-1; IPP1; Ppp1r1a; PPR1A_HUMAN; Protein phosphatase 1 regulatory (inhibitor) subunit 1A; Protein phosphatase 1 regulatory subunit 1A; Protein phosphatase inhibitor 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-171
  • 氨基酸序列
    MEQDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI DEDRIPNPHL KSTLAMSPRQ RKKMTRITPT MKELQMMVEH HLGQQQQGEE PEGAAESTET QESRPPGIPD TEVESRLGTS GTAKKTAECI PKTHERGSKE PSTKEPSTHI PPLDSKGANS V
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
  • 基因功能參考文獻:
    1. These findings suggest that the human G109E inhibitor-1 variant impairs sarcoplasmic reticulum Ca-cycling and promotes arrhythmogenesis under stress conditions. PMID: 26455482
    2. I-1 and sarco/endoplasmic reticulum Ca2+ -ATPase synergistically induce the vascular smooth muscle cell contractile phenotype. PMID: 24249716
    3. multiple domains in I-1 target cellular PP1 complexes, and I-1 has a role as a cellular regulator of eIF2alpha phosphorylation PMID: 15345721
    4. G147D PPI-1 can attenuate responses of cardiomyocytes to beta-adrenergic agonists by decreasing PLN phosphorylation and therefore may contribute to deteriorated function in heart failure. PMID: 18192322
    5. the human inhibitor-1 G147D polymorphism, found almost exclusively in blacks, may act as a modifier rather than risk factor in heart failure development PMID: 18698139

    顯示更多

    收起更多

  • 蛋白家族:
    Protein phosphatase inhibitor 1 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 9286

    OMIM: 613246

    KEGG: hsa:5502

    STRING: 9606.ENSP00000257905

    UniGene: Hs.505662



主站蜘蛛池模板: 久久国产欧美日韩精品| 国产福利在线永久视频| 精品人无码一区二区三区| 日产精品一区二区| 午夜福利三级理论电影| 中文字幕在线观看亚洲视频| 久精品国产欧美亚洲色aⅴ大片| 精品日本免费一区二区三区| 熟妇的奶头又大又长奶水视频| 国模丽丽啪啪一区二区| 装睡被陌生人摸出水好爽| 亚洲女教师丝祙在线播放| 撕开奶罩揉吃奶高潮av在线观看| 亚洲中文字幕无码久久2018| 色www视频永久免费| 国产精品久久久亚洲| 亚洲国产人成自精在线尤物| 国产一区二区不卡在线看| 少妇高潮大叫好爽| 久久国语露脸国产精品电影| 久久se精品一区精品二区| 国产亚洲精品久久久久久国| 人摸人人人澡人人超碰97| 欧美黑人乱大交| 五月天激情电影| 亚洲成片在线观看12345| 国产99久久久欧美黑人刘玥| 日本成aⅴ人片日本伦| 男人a天堂手机在线版| 蜜桃传媒av免费观看麻豆| 老熟妇性老熟妇性色| 又黄又爽又无遮挡免费的网站| 国产嘿嘿嘿视频在线观看| 久久国产人妻一区二区免费| 天天爱天天做狠狠久久做| 精品一区二区ww| 国产精品96久久久久久av网址| 中文在线天堂а√在线| 国产999精品久久久久久| 亚洲精品色无码av试看| 亚洲人成网站18禁止中文字幕|